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The map label for this gene is fucA [H]

Identifier: 238026933

GI number: 238026933

Start: 1428772

End: 1429554

Strand: Direct

Name: fucA [H]

Synonym: bglu_1g13050

Alternate gene names: 238026933

Gene position: 1428772-1429554 (Clockwise)

Preceding gene: 238026930

Following gene: 238026934

Centisome position: 36.57

GC content: 67.69

Gene sequence:

>783_bases
ATGGCCGAAACGCTGAGTCTGTCGAAATCCGAGCTGGTTGCCCGTTCGCAGGCGCAACTGGATACCACGCTGTCCGTGCG
CAACTGGACGACGCGCCAGAAGCTGGCCCTGACGTGCCGCATTCTATTCGACGGCGGCCACGATTCGGGCCTCGCCGGCC
AGATCACGGCGCGCGCCGAGGATCCCGACACCTATTACACCCAGCCGTTCGGCCATGGTTTCGACGAGATCACCGAGACG
AACCTGCTGGTGGTCGACCAGGACCTGAAGACGGTGGACGGCCGCGGCATGCCGAATCCGGCGAATCGCTTCCACACCTG
GGTCTACCGCGCGCGCCCCGATGTGAACTGCATCATCCACACCCATCCGCTGCACGTCTCGGCGCTGTCGATGCTGGAAG
TGCCGCTGGCCGTGTCGCACATGGATACCTGCCCGCTCTACGACGATTGCGCGTTCCTCGAAAAATGGCCCGGCGTGCCG
GTGGGCAACGAGGAGGGCGAGATCATCTCGGCCGCGCTCGGCGGCAAGCGCGCGGTGCTGCTCGCGCATCATGGCATGCT
GGTGACCGGCAAGACCGTCGAGGAAGCGTGCTCGCTCGCGCTGCTGATGGAGCGCGCCGCGCGCCTGCAACTCGCCGCGA
TGGCCGCCGGCCCGATCCGCCCGATCCCCGAGGCTCTCGCCGCCGAGGCGCACGACTGGATCTCGACGCCGAAGCGCCAC
GCCGTCGCCTTCGACTATTACGCGCGCCGCGCGCTGCGCGCCCATCCCGACTGTCTGGCCTGA

Upstream 100 bases:

>100_bases
TTTATCGTTGAATGACACGTCGTGTCATATAATACCCAGCGTGTACTGTCGGCACGATGCCGGTCGCCCGACATCCGCCG
GTTCACCTGGAGATGCTGCA

Downstream 100 bases:

>100_bases
TCCCGGGCGGACGCAGCGCACTGCGCCGGCCCGATGTGGGGGCGCATCGCGCCGGCCAACCGCTGGTGCTCAAGCGCGCT
GTCGACGCAATTCCCCGACG

Product: class II aldolase/adducin domain protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAETLSLSKSELVARSQAQLDTTLSVRNWTTRQKLALTCRILFDGGHDSGLAGQITARAEDPDTYYTQPFGHGFDEITET
NLLVVDQDLKTVDGRGMPNPANRFHTWVYRARPDVNCIIHTHPLHVSALSMLEVPLAVSHMDTCPLYDDCAFLEKWPGVP
VGNEEGEIISAALGGKRAVLLAHHGMLVTGKTVEEACSLALLMERAARLQLAAMAAGPIRPIPEALAAEAHDWISTPKRH
AVAFDYYARRALRAHPDCLA

Sequences:

>Translated_260_residues
MAETLSLSKSELVARSQAQLDTTLSVRNWTTRQKLALTCRILFDGGHDSGLAGQITARAEDPDTYYTQPFGHGFDEITET
NLLVVDQDLKTVDGRGMPNPANRFHTWVYRARPDVNCIIHTHPLHVSALSMLEVPLAVSHMDTCPLYDDCAFLEKWPGVP
VGNEEGEIISAALGGKRAVLLAHHGMLVTGKTVEEACSLALLMERAARLQLAAMAAGPIRPIPEALAAEAHDWISTPKRH
AVAFDYYARRALRAHPDCLA
>Mature_259_residues
AETLSLSKSELVARSQAQLDTTLSVRNWTTRQKLALTCRILFDGGHDSGLAGQITARAEDPDTYYTQPFGHGFDEITETN
LLVVDQDLKTVDGRGMPNPANRFHTWVYRARPDVNCIIHTHPLHVSALSMLEVPLAVSHMDTCPLYDDCAFLEKWPGVPV
GNEEGEIISAALGGKRAVLLAHHGMLVTGKTVEEACSLALLMERAARLQLAAMAAGPIRPIPEALAAEAHDWISTPKRHA
VAFDYYARRALRAHPDCLA

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=201, Percent_Identity=29.8507462686567, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533216, Length=196, Percent_Identity=27.0408163265306, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71989560, Length=199, Percent_Identity=31.6582914572864, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989544, Length=199, Percent_Identity=31.6582914572864, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989541, Length=199, Percent_Identity=31.6582914572864, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533218, Length=196, Percent_Identity=27.0408163265306, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989550, Length=199, Percent_Identity=31.6582914572864, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989555, Length=199, Percent_Identity=31.6582914572864, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363763, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363757, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17136738, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363755, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363751, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24655690, Length=191, Percent_Identity=30.8900523560209, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24655685, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363761, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281363759, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281363753, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 28484; Mature: 28353

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLSLSKSELVARSQAQLDTTLSVRNWTTRQKLALTCRILFDGGHDSGLAGQITARAE
CCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECC
DPDTYYTQPFGHGFDEITETNLLVVDQDLKTVDGRGMPNPANRFHTWVYRARPDVNCIIH
CCCCEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEE
THPLHVSALSMLEVPLAVSHMDTCPLYDDCAFLEKWPGVPVGNEEGEIISAALGGKRAVL
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCEEEE
LAHHGMLVTGKTVEEACSLALLMERAARLQLAAMAAGPIRPIPEALAAEAHDWISTPKRH
EEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHH
AVAFDYYARRALRAHPDCLA
EEEHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AETLSLSKSELVARSQAQLDTTLSVRNWTTRQKLALTCRILFDGGHDSGLAGQITARAE
CCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECC
DPDTYYTQPFGHGFDEITETNLLVVDQDLKTVDGRGMPNPANRFHTWVYRARPDVNCIIH
CCCCEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEE
THPLHVSALSMLEVPLAVSHMDTCPLYDDCAFLEKWPGVPVGNEEGEIISAALGGKRAVL
ECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCEEEE
LAHHGMLVTGKTVEEACSLALLMERAARLQLAAMAAGPIRPIPEALAAEAHDWISTPKRH
EEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHH
AVAFDYYARRALRAHPDCLA
EEEHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]