Click here to switch to the map view.

The map label for this gene is zwf [H]

Identifier: 238026931

GI number: 238026931

Start: 1426186

End: 1427661

Strand: Reverse

Name: zwf [H]

Synonym: bglu_1g13030

Alternate gene names: 238026931

Gene position: 1427661-1426186 (Counterclockwise)

Preceding gene: 238026932

Following gene: 238026923

Centisome position: 36.55

GC content: 67.62

Gene sequence:

>1476_bases
ATGACGAATCAGCCCAACCCGACCGCATCCGAACTGCCCGTCGACATGATCATCTTCGGCGGCGGCGGCGACCTCGCCGC
CCGCAAGCTGCTGCCCGCGCTGTACATGGCGCACCTGCACCGCAACCTGCCGCCCGAGACGCGCATCATCGCGGTCGGCC
GGCGCGACTGGGGCATCGACGGCTACCGCAGGTTCATGGAGGAGCAGTCGCGGCCGTTCATCGACGCGAAGGCATTCGAC
GCGCAGGCCTGGAACCACTTCCTCGATCTGTTCCAGTACACGCTGATCGACGTCAACGAGCCGGGCGACTACCAACGGCT
CGCCGAGGCCTCGCGCAGCGAGGCGATCCGCGTGTTCTACCTGTCCACCTCGCCCGAGCTGTTCACGACCATCTGCGACA
ACCTCTCGGCCGCCGGTCTGGTCGACGCGCATTCGCGCGTAGTGCTGGAAAAGCCGCTCGGCCACGACCTGGCCTCGGCG
CAGGCGATCAACAACGCGGTCGGCAGGCATTTCGCCGAATCGCAGATCTACCGGATCGACCACTATCTCGGCAAGGAAAC
GGTGCAGAACCTGATGGTGCTGCGTTTCGGCAACCCGATCTTCGGGCCGCTGTGGCAGGCGCCATACATCCGCAGCGTGC
AGATCACGGTGGCCGAGACGGTCGGCGTGGGCAGCCGCGCCGGCTTCTACGATCACACCGGCGCGCTGCGCGACATGGTG
CAGAACCACCTGCTGCAGCTGCTGTGCATCGTGGCGATGGAGCCGCCCGTCTCGCTCGACCCCGACGCGGTGCGCGACGA
AAAGCTGAAGGTGCTGCGCTCGCTGCGGCCGATGACGCCCGCCGACATCGCCCGCGACACGGTGCGCGGCCAGTACGCGG
CCGGCGCCGTGGACGGCAAGCCCGTCAAGGGCTATCTGGAAGAGGACAACGTGCCGGCCGACAGCCGCGCGGAGACTTTC
GTCGCGCTGCGCGCGCACATCAACAACTGGCGCTGGGCCAACGTGCCGTTCTTCCTGCGCACCGGCAAGCGGATGCAGAA
GCGCCAGTCGGAGATCGTCATCGAGTTCGCCGATCTGCCGTTCTCGATCATCCCGAACGGCCCGCGCCACTACAGCAACC
GGCTCGTGATCCAGTTGCAGCCCGAGGAATCGATCCAGCTGCAGATGCTCGCGAAGGAACCGGGCAGCGGCATGAACATG
GTGCCCGTCAGCCTCAACCTCGACCTGCAGCAGGCGATCCCCGAGCGGCGCGCCGAAGCCTACGAGCGGCTGCTGATCGA
CGTGATCCGCGGCCGCCTCACCCATTTCATGCGCCGCGACGAACTGGAAGCGGCCTGGACCTGGATCGAGCCGATCCTCG
ACGGCTGGCATCAGCCCGGCGACCGGCCGCGGCTCTACACGGCGGGCACCTTCGGGCCGGCCGCGTCGTCGGCGCTGCTC
GCGCGTGACAACATGTCGTGGGCCGAGGAGGCCTGA

Upstream 100 bases:

>100_bases
GAGTCACGCAAAACCGTGCAAACTAGGACTTTCCGCCGCACTGCGGCATGCCGCACCACCTTTCGTTCAACGCTCATCGA
TCTTGACCCGCGAACCACCC

Downstream 100 bases:

>100_bases
GCCTCGCCCGCAGGGCGGCGGCGCCCGCCGCCCGCCCTGCCGCCCGCCGCGTCACCGTGCCGCCGTCGGTCGTGCGATCC
GCGTCCGTCATGGAACCCGA

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTNQPNPTASELPVDMIIFGGGGDLAARKLLPALYMAHLHRNLPPETRIIAVGRRDWGIDGYRRFMEEQSRPFIDAKAFD
AQAWNHFLDLFQYTLIDVNEPGDYQRLAEASRSEAIRVFYLSTSPELFTTICDNLSAAGLVDAHSRVVLEKPLGHDLASA
QAINNAVGRHFAESQIYRIDHYLGKETVQNLMVLRFGNPIFGPLWQAPYIRSVQITVAETVGVGSRAGFYDHTGALRDMV
QNHLLQLLCIVAMEPPVSLDPDAVRDEKLKVLRSLRPMTPADIARDTVRGQYAAGAVDGKPVKGYLEEDNVPADSRAETF
VALRAHINNWRWANVPFFLRTGKRMQKRQSEIVIEFADLPFSIIPNGPRHYSNRLVIQLQPEESIQLQMLAKEPGSGMNM
VPVSLNLDLQQAIPERRAEAYERLLIDVIRGRLTHFMRRDELEAAWTWIEPILDGWHQPGDRPRLYTAGTFGPAASSALL
ARDNMSWAEEA

Sequences:

>Translated_491_residues
MTNQPNPTASELPVDMIIFGGGGDLAARKLLPALYMAHLHRNLPPETRIIAVGRRDWGIDGYRRFMEEQSRPFIDAKAFD
AQAWNHFLDLFQYTLIDVNEPGDYQRLAEASRSEAIRVFYLSTSPELFTTICDNLSAAGLVDAHSRVVLEKPLGHDLASA
QAINNAVGRHFAESQIYRIDHYLGKETVQNLMVLRFGNPIFGPLWQAPYIRSVQITVAETVGVGSRAGFYDHTGALRDMV
QNHLLQLLCIVAMEPPVSLDPDAVRDEKLKVLRSLRPMTPADIARDTVRGQYAAGAVDGKPVKGYLEEDNVPADSRAETF
VALRAHINNWRWANVPFFLRTGKRMQKRQSEIVIEFADLPFSIIPNGPRHYSNRLVIQLQPEESIQLQMLAKEPGSGMNM
VPVSLNLDLQQAIPERRAEAYERLLIDVIRGRLTHFMRRDELEAAWTWIEPILDGWHQPGDRPRLYTAGTFGPAASSALL
ARDNMSWAEEA
>Mature_490_residues
TNQPNPTASELPVDMIIFGGGGDLAARKLLPALYMAHLHRNLPPETRIIAVGRRDWGIDGYRRFMEEQSRPFIDAKAFDA
QAWNHFLDLFQYTLIDVNEPGDYQRLAEASRSEAIRVFYLSTSPELFTTICDNLSAAGLVDAHSRVVLEKPLGHDLASAQ
AINNAVGRHFAESQIYRIDHYLGKETVQNLMVLRFGNPIFGPLWQAPYIRSVQITVAETVGVGSRAGFYDHTGALRDMVQ
NHLLQLLCIVAMEPPVSLDPDAVRDEKLKVLRSLRPMTPADIARDTVRGQYAAGAVDGKPVKGYLEEDNVPADSRAETFV
ALRAHINNWRWANVPFFLRTGKRMQKRQSEIVIEFADLPFSIIPNGPRHYSNRLVIQLQPEESIQLQMLAKEPGSGMNMV
PVSLNLDLQQAIPERRAEAYERLLIDVIRGRLTHFMRRDELEAAWTWIEPILDGWHQPGDRPRLYTAGTFGPAASSALLA
RDNMSWAEEA

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=477, Percent_Identity=37.3165618448637, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI109389365, Length=477, Percent_Identity=37.3165618448637, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI52145310, Length=497, Percent_Identity=29.5774647887324, Blast_Score=173, Evalue=3e-43,
Organism=Escherichia coli, GI1788158, Length=487, Percent_Identity=44.7638603696099, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17538218, Length=485, Percent_Identity=36.701030927835, Blast_Score=326, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6324088, Length=493, Percent_Identity=34.2799188640974, Blast_Score=280, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24643352, Length=487, Percent_Identity=35.7289527720739, Blast_Score=312, Evalue=4e-85,
Organism=Drosophila melanogaster, GI24643350, Length=487, Percent_Identity=35.7289527720739, Blast_Score=311, Evalue=5e-85,
Organism=Drosophila melanogaster, GI221513548, Length=476, Percent_Identity=30.0420168067227, Blast_Score=215, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 55268; Mature: 55137

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQPNPTASELPVDMIIFGGGGDLAARKLLPALYMAHLHRNLPPETRIIAVGRRDWGID
CCCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
GYRRFMEEQSRPFIDAKAFDAQAWNHFLDLFQYTLIDVNEPGDYQRLAEASRSEAIRVFY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCEEEEEE
LSTSPELFTTICDNLSAAGLVDAHSRVVLEKPLGHDLASAQAINNAVGRHFAESQIYRID
EECCHHHHHHHHHCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HYLGKETVQNLMVLRFGNPIFGPLWQAPYIRSVQITVAETVGVGSRAGFYDHTGALRDMV
HHHCHHHHHHHEEHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
QNHLLQLLCIVAMEPPVSLDPDAVRDEKLKVLRSLRPMTPADIARDTVRGQYAAGAVDGK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCC
PVKGYLEEDNVPADSRAETFVALRAHINNWRWANVPFFLRTGKRMQKRQSEIVIEFADLP
CCCCEECCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEECCCHHHHHHHHHEEEEEECCC
FSIIPNGPRHYSNRLVIQLQPEESIQLQMLAKEPGSGMNMVPVSLNLDLQQAIPERRAEA
EEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHH
YERLLIDVIRGRLTHFMRRDELEAAWTWIEPILDGWHQPGDRPRLYTAGTFGPAASSALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCHHE
ARDNMSWAEEA
ECCCCCHHCCC
>Mature Secondary Structure 
TNQPNPTASELPVDMIIFGGGGDLAARKLLPALYMAHLHRNLPPETRIIAVGRRDWGID
CCCCCCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
GYRRFMEEQSRPFIDAKAFDAQAWNHFLDLFQYTLIDVNEPGDYQRLAEASRSEAIRVFY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCEEEEEE
LSTSPELFTTICDNLSAAGLVDAHSRVVLEKPLGHDLASAQAINNAVGRHFAESQIYRID
EECCHHHHHHHHHCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HYLGKETVQNLMVLRFGNPIFGPLWQAPYIRSVQITVAETVGVGSRAGFYDHTGALRDMV
HHHCHHHHHHHEEHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHH
QNHLLQLLCIVAMEPPVSLDPDAVRDEKLKVLRSLRPMTPADIARDTVRGQYAAGAVDGK
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCC
PVKGYLEEDNVPADSRAETFVALRAHINNWRWANVPFFLRTGKRMQKRQSEIVIEFADLP
CCCCEECCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEECCCHHHHHHHHHEEEEEECCC
FSIIPNGPRHYSNRLVIQLQPEESIQLQMLAKEPGSGMNMVPVSLNLDLQQAIPERRAEA
EEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHH
YERLLIDVIRGRLTHFMRRDELEAAWTWIEPILDGWHQPGDRPRLYTAGTFGPAASSALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCHHE
ARDNMSWAEEA
ECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA