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The map label for this gene is dinF [H]

Identifier: 238026828

GI number: 238026828

Start: 1303303

End: 1304664

Strand: Reverse

Name: dinF [H]

Synonym: bglu_1g11880

Alternate gene names: 238026828

Gene position: 1304664-1303303 (Counterclockwise)

Preceding gene: 238026829

Following gene: 238026824

Centisome position: 33.4

GC content: 73.13

Gene sequence:

>1362_bases
ATGTCGTCCTCCTCCGCGTTGTCCACCGGGGCCGCGGCCGGCCACGCCGGCGTCGGCCACCGCAGGGTGCTCGGCCTCGC
CGTGCCGATCATGCTCGCGAACCTGACGCAGCCGATTCTCGGCGCCGTCGACACCGCCGTGGCCGGCCATCTCGAGGGCG
CGCAGATGCTGGGCGGCGTGGCGCTGGGCAGCCTGTTCTTCGGGTTCGTCTACTGGGGCTTCGGCTTCCTGCGGATGGGC
ACGACCGGGCTCGTCGCGCAGGCGTATGGCGCCGGCGACCAGGCCGGCATCCGCCTCAACCTGCTGCGCGCGCTCGTGCT
GGCCGGCCTGCTCGGCTTCGCCGTGCTCGCGCTGCACGGCCCGCTGATCTCGATCGCGCTGACACTGCTCGGCGGCAGCG
AGGCGGTACGCGCCACCGCGCGCGGCTACGTGCTGGCGCGGATCTGGGCCGCGCCGTTCGCGCTGGCCAACTACGCGATC
CTCGGCTACCTGCTCGGCGTGCAGCGCGTGCGGCTCGCGCTCGCGCTGCAGGCTTTCATCAACCTCGTAAACATCGTCGC
GGTGATGCTGTTCGTCTACCGCTTCGACGGGGGCGTGGCCGGCATCGGCGCGGCCACGGCGGCGGCCGATCTGGCGGGCT
TCGGGTTCGGCGTGCTCGCGCTCGCGCGGCGGCGCCAGCGCGGGCTAGGCAGGCCGAGCTGGCGCCAGCTCCTCGATCGG
GCCGCGCTCGAGCGGCTGGTCGCGCTCAACCGCGATATCTTCGTGCGCACGCTCTGCCTGCTGTCGGCGTTCGGCTGGTT
CGCGCATCTCGGCGCGCGGCAAGGCGATACGATGCTCGCCGCCAATGCGCTGCTGCTCAACTTCCAGACCTTCATGGCCT
ACGCGCTCGACGGCTTCGCGCATGCGGCCGAGGCGCTGGTCGGCGCGGCCGCCGGCGCACGCGACCGGGCGATGTTCCGC
GCCACGCTGCGCGTCACGCTGCAATGGGCCGCCGGCTGCGCGCTCGCGTTCTGCGCCGCCTACGCGCTCGGCGGCGGCTG
GATCATCGCGCGGCTCAGCGACCAGCCCGCGATCCGCGCGGCGGCCGGCCACTTCCTGCCGTGGGCGGCCGCGATGCCGC
TCGTGTCGGTGTGGGGGTTCCTGCTCGACGGCGTGTTCATCGGCGCCACCCGGACGCGCGCGCTGATGGTAGCGATGGCC
GTGTCGCTCGGCGTATTCGTCGCCGCGACCCTGGTACTGACCGGGCCGCTCGGCAATCACGGGCTCTGGCTCGCGATGTC
GATCTTCATGATCGCGCGCGGCGTGACGCTGGCGAGCCGGATGCCGGCGCTGTCGCGACAGATCGGCGGCGAAGGGACCT
AG

Upstream 100 bases:

>100_bases
CGCAGGACTACGCGGCACGCACGCCCGAGCTGTGGGCCGTGGTCGTGTCGCCATGGATCTGCGTGCAGGAGCGCGCACCG
GAACGCTCCTAGGCGGCGCG

Downstream 100 bases:

>100_bases
CCGCGTGGCGGACGTCGGCGTGGCGGAGCGCGCGGCGACGCCGGTGACGGCCCGAAACCGGGCACCGCCGGCACGCGCGC
GAGCCGCCCGCGCGGCCGCT

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSSSSALSTGAAAGHAGVGHRRVLGLAVPIMLANLTQPILGAVDTAVAGHLEGAQMLGGVALGSLFFGFVYWGFGFLRMG
TTGLVAQAYGAGDQAGIRLNLLRALVLAGLLGFAVLALHGPLISIALTLLGGSEAVRATARGYVLARIWAAPFALANYAI
LGYLLGVQRVRLALALQAFINLVNIVAVMLFVYRFDGGVAGIGAATAAADLAGFGFGVLALARRRQRGLGRPSWRQLLDR
AALERLVALNRDIFVRTLCLLSAFGWFAHLGARQGDTMLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARDRAMFR
ATLRVTLQWAAGCALAFCAAYALGGGWIIARLSDQPAIRAAAGHFLPWAAAMPLVSVWGFLLDGVFIGATRTRALMVAMA
VSLGVFVAATLVLTGPLGNHGLWLAMSIFMIARGVTLASRMPALSRQIGGEGT

Sequences:

>Translated_453_residues
MSSSSALSTGAAAGHAGVGHRRVLGLAVPIMLANLTQPILGAVDTAVAGHLEGAQMLGGVALGSLFFGFVYWGFGFLRMG
TTGLVAQAYGAGDQAGIRLNLLRALVLAGLLGFAVLALHGPLISIALTLLGGSEAVRATARGYVLARIWAAPFALANYAI
LGYLLGVQRVRLALALQAFINLVNIVAVMLFVYRFDGGVAGIGAATAAADLAGFGFGVLALARRRQRGLGRPSWRQLLDR
AALERLVALNRDIFVRTLCLLSAFGWFAHLGARQGDTMLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARDRAMFR
ATLRVTLQWAAGCALAFCAAYALGGGWIIARLSDQPAIRAAAGHFLPWAAAMPLVSVWGFLLDGVFIGATRTRALMVAMA
VSLGVFVAATLVLTGPLGNHGLWLAMSIFMIARGVTLASRMPALSRQIGGEGT
>Mature_452_residues
SSSSALSTGAAAGHAGVGHRRVLGLAVPIMLANLTQPILGAVDTAVAGHLEGAQMLGGVALGSLFFGFVYWGFGFLRMGT
TGLVAQAYGAGDQAGIRLNLLRALVLAGLLGFAVLALHGPLISIALTLLGGSEAVRATARGYVLARIWAAPFALANYAIL
GYLLGVQRVRLALALQAFINLVNIVAVMLFVYRFDGGVAGIGAATAAADLAGFGFGVLALARRRQRGLGRPSWRQLLDRA
ALERLVALNRDIFVRTLCLLSAFGWFAHLGARQGDTMLAANALLLNFQTFMAYALDGFAHAAEALVGAAAGARDRAMFRA
TLRVTLQWAAGCALAFCAAYALGGGWIIARLSDQPAIRAAAGHFLPWAAAMPLVSVWGFLLDGVFIGATRTRALMVAMAV
SLGVFVAATLVLTGPLGNHGLWLAMSIFMIARGVTLASRMPALSRQIGGEGT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=419, Percent_Identity=42.2434367541766, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI48994890, Length=446, Percent_Identity=24.8878923766816, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47057; Mature: 46926

Theoretical pI: Translated: 11.77; Mature: 11.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCC
>Mature Secondary Structure 
SSSSALSTGAAAGHAGVGHRRVLGLAVPIMLANLTQPILGAVDTAVAGHLEGAQMLGGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ALGSLFFGFVYWGFGFLRMGTTGLVAQAYGAGDQAGIRLNLLRALVLAGLLGFAVLALHG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PLISIALTLLGGSEAVRATARGYVLARIWAAPFALANYAILGYLLGVQRVRLALALQAFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLVNIVAVMLFVYRFDGGVAGIGAATAAADLAGFGFGVLALARRRQRGLGRPSWRQLLDR
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AALERLVALNRDIFVRTLCLLSAFGWFAHLGARQGDTMLAANALLLNFQTFMAYALDGFA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HAAEALVGAAAGARDRAMFRATLRVTLQWAAGCALAFCAAYALGGGWIIARLSDQPAIRA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
AAGHFLPWAAAMPLVSVWGFLLDGVFIGATRTRALMVAMAVSLGVFVAATLVLTGPLGNH
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLWLAMSIFMIARGVTLASRMPALSRQIGGEGT
HHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]