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The map label for this gene is pccB [H]

Identifier: 238026760

GI number: 238026760

Start: 1228309

End: 1229223

Strand: Direct

Name: pccB [H]

Synonym: bglu_1g11180

Alternate gene names: 238026760

Gene position: 1228309-1229223 (Clockwise)

Preceding gene: 238026759

Following gene: 238026761

Centisome position: 31.44

GC content: 74.43

Gene sequence:

>915_bases
ATGAACGGCGTCGATCCGATCGCGGCCGGCGCGAGCTGGTACGAGGCGTCGGCACGCCAGCGCATCGACGGGCTGGTCGA
CGCCGGCACGTTCGCCGAGTTCGTCGGGCCGGCCGAGCGCGAGATGAGCCCGCACCTGCCGCTGTTCGACCTGCCGCGCC
AGTTCGACGACGGCATGATCGTCGGGCGTGCCGCGCTCGACGGCCGCGCGGTGCTGGTGGCCGCGCAGGAAGGGCGCTTC
ATGGGCGGCGCGTTCGGCGAGGTGCACGGCGCCAAGCTCACCGGGCTGCTGCGCGCGGCGCGCGAGCTCGGCATGCCGGT
GCTGGTCCTGTTCGATACCGGCGGCGTGCGGCTGCAGGAGGCCAACGCGGGCGAGCTCGCGATCGCCGAGATCATGCGCG
CGCTGATCGATGCGCGTGCGGCCGGCGTGCCGGTGATCGGGCTGGTCGGCGGGCGGGCCGGCTGCTATGGCGGCGGCGGC
CTGCTGGCCGCCTGCTGCTCGGCGCTGGCGGTGTCGGAGCCGGGGCGCATCGGCGTGTCGGGGCCGGAGGTGATCGAGAC
CAATCGCGGCGTCGAGGAATTCGACTCGAAGGACCGCGCGCTGGTCTGGCGCACCATGGGCGGCAAGCATCGCCGCCTGA
TCGGCGGCGTCGAGCGCTTCGTCGAGGACACGCTGCCGGCGTTCCGTGCCGCGGCGCTCGCGCTGCTCGCGGCGCCCCAC
GGCTTCGATCTGGACCTGCTCGAGGCCGAACAGAGGCGGCTCGAGGCGCGGCTCGCCGCGTTCGACGATTGCGGCGACGC
GCGCGAAATCTGGCGCCGGCTCGGCGCGACCGAAGCCGAGGCCGAGGCGATTCCCGCGATGCCCGGCGAGACCTTCGCCG
CGCTCGCCGAGCGCCTTCAGGGAGGCGCGCGATGA

Upstream 100 bases:

>100_bases
CCGGCGGCCTGCGGCTGTCGATCAACGACGGCGGCGCGCGGCCCGACACGGTCGCGCTGCGGCTCGCGCAGGCGGTGCGC
GCGATCGAGGGAGGCGCGCG

Downstream 100 bases:

>100_bases
CGCTCGACGACATTCTCGCGTCGTTCGACCACGACGTGTCCCGCCGCGACGACGGCCTGCTGGCCGGCCGCGCCACGCTC
GACGGCCGGCGCGTGGACCT

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNGVDPIAAGASWYEASARQRIDGLVDAGTFAEFVGPAEREMSPHLPLFDLPRQFDDGMIVGRAALDGRAVLVAAQEGRF
MGGAFGEVHGAKLTGLLRAARELGMPVLVLFDTGGVRLQEANAGELAIAEIMRALIDARAAGVPVIGLVGGRAGCYGGGG
LLAACCSALAVSEPGRIGVSGPEVIETNRGVEEFDSKDRALVWRTMGGKHRRLIGGVERFVEDTLPAFRAAALALLAAPH
GFDLDLLEAEQRRLEARLAAFDDCGDAREIWRRLGATEAEAEAIPAMPGETFAALAERLQGGAR

Sequences:

>Translated_304_residues
MNGVDPIAAGASWYEASARQRIDGLVDAGTFAEFVGPAEREMSPHLPLFDLPRQFDDGMIVGRAALDGRAVLVAAQEGRF
MGGAFGEVHGAKLTGLLRAARELGMPVLVLFDTGGVRLQEANAGELAIAEIMRALIDARAAGVPVIGLVGGRAGCYGGGG
LLAACCSALAVSEPGRIGVSGPEVIETNRGVEEFDSKDRALVWRTMGGKHRRLIGGVERFVEDTLPAFRAAALALLAAPH
GFDLDLLEAEQRRLEARLAAFDDCGDAREIWRRLGATEAEAEAIPAMPGETFAALAERLQGGAR
>Mature_304_residues
MNGVDPIAAGASWYEASARQRIDGLVDAGTFAEFVGPAEREMSPHLPLFDLPRQFDDGMIVGRAALDGRAVLVAAQEGRF
MGGAFGEVHGAKLTGLLRAARELGMPVLVLFDTGGVRLQEANAGELAIAEIMRALIDARAAGVPVIGLVGGRAGCYGGGG
LLAACCSALAVSEPGRIGVSGPEVIETNRGVEEFDSKDRALVWRTMGGKHRRLIGGVERFVEDTLPAFRAAALALLAAPH
GFDLDLLEAEQRRLEARLAAFDDCGDAREIWRRLGATEAEAEAIPAMPGETFAALAERLQGGAR

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=181, Percent_Identity=30.3867403314917, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788655, Length=185, Percent_Identity=30.2702702702703, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=184, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147359, Length=184, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 31957; Mature: 31957

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGVDPIAAGASWYEASARQRIDGLVDAGTFAEFVGPAEREMSPHLPLFDLPRQFDDGMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHCCCCCCCCEE
VGRAALDGRAVLVAAQEGRFMGGAFGEVHGAKLTGLLRAARELGMPVLVLFDTGGVRLQE
EEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEE
ANAGELAIAEIMRALIDARAAGVPVIGLVGGRAGCYGGGGLLAACCSALAVSEPGRIGVS
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
GPEVIETNRGVEEFDSKDRALVWRTMGGKHRRLIGGVERFVEDTLPAFRAAALALLAAPH
CCCHHHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDLDLLEAEQRRLEARLAAFDDCGDAREIWRRLGATEAEAEAIPAMPGETFAALAERLQ
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHC
GGAR
CCCC
>Mature Secondary Structure
MNGVDPIAAGASWYEASARQRIDGLVDAGTFAEFVGPAEREMSPHLPLFDLPRQFDDGMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHCCCCCCCCEE
VGRAALDGRAVLVAAQEGRFMGGAFGEVHGAKLTGLLRAARELGMPVLVLFDTGGVRLQE
EEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEE
ANAGELAIAEIMRALIDARAAGVPVIGLVGGRAGCYGGGGLLAACCSALAVSEPGRIGVS
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
GPEVIETNRGVEEFDSKDRALVWRTMGGKHRRLIGGVERFVEDTLPAFRAAALALLAAPH
CCCHHHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFDLDLLEAEQRRLEARLAAFDDCGDAREIWRRLGATEAEAEAIPAMPGETFAALAERLQ
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHC
GGAR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]