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The map label for this gene is uvrC [H]

Identifier: 238026626

GI number: 238026626

Start: 1048848

End: 1051118

Strand: Direct

Name: uvrC [H]

Synonym: bglu_1g09730

Alternate gene names: 238026626

Gene position: 1048848-1051118 (Clockwise)

Preceding gene: 238026622

Following gene: 339905961

Centisome position: 26.85

GC content: 70.45

Gene sequence:

>2271_bases
ATGACATCCCCCGATACCTCCGATCGCCCCGAAGCCTCTGGCCATGGTGGCCAGCCAGCCCCGGCGAGCCAGGCCGCCGC
GCCATTCGAGCCGAAGCCGGTCCTCGCGCAATTGCCGCATCTGCCGGGCGTCTACCGGTATTACGACGCCGCCGGCTCGG
TGCTCTACGTGGGCAAGGCGCGCAACCTGAAAAAGCGCGTCTCGAGCTATTTCACGAAGACCCAGCTTTCGCCGCGCATC
GCGATGATGGTCACGCGGATCGCCAGGATCGAGACCACGGTGACGCGCTCGGAGGCCGAGGCGCTGCTGCTCGAAAACAA
TCTGATCAAGGCGCTCGCGCCGCGCTACAACATCCTGTTTCGCGACGACAAGTCGTATCCGTATCTGAAGCTGACCGGTC
ATGCGTTTCCGCGCATGGCCTATTACCGCGGCGCCGTCGATCGCAAGAACCAGTATTTCGGGCCGTTTCCGAGCGCCTGG
GCGGTGCGCGAGAGCATCCAGATCCTGCAGCGCGTGTTCCAGCTGCGCACCTGCGAGGATTCGGTGTTCAACAACCGCAC
GCGCCCCTGCCTGCTGCACCAGATCGGCCGCTGCTCCGCGCCGTGCGTGGGCGCGATCGACGCCGCGGACTACGCGCGCG
ACGTCGCGAACGCCTCGCGCTTCCTGCTCGGCCGGCAGAGCGAAGTGATGAAGGAACTCGAGCAGAAGATGCACGGTTTC
GCCGCGGAACTGAAGTTCGAGCAGGCGGCCGCGGTGCGCAACCAGATGAGCTCGCTCGCCACGGTGCTGCATCAGCAGGC
GATCGAGGTCGGCAGCGAGAGCGATGTCGACATCCTCGCCGTGGTCGCGCACGGCGGGCGGGTCTGCGTCAATCTCGCGA
TGGTGCGCGGCGGGCGGCACCTCGGCGACAAGGCCTACTTCCCCGCGCACGCCGACGGCGCGCTGGCGGCGGGCGGGGCG
CAGCAGGCGGCGCCGGACGAGGACGCGGGCGCGATCGTCGAGGATCCCGCGGCGCTGGCCGGCGCCGTGCCGGACGCCGC
TGCTGCTGCTGCTGCTGCTGCTGCCGTTGTCGCCGTCGAGACGCCGGCCGCTGCCGGGTCCGACGATCCCGCGCGCGCGC
CGGATCACGCGGCGCCGGCTCCGGCCGCGGCCGAGGCCGGCGGCGCGCGCGGTGCCGACGAAGCCGTGCCGCCGGCGGAG
GGCCCACCAGCCGTCGCCGAAGCCGATGACGACGCCGAATCGGTTGCCGCGCCGATCGAGACCGAAGTGCTGGAGGCGTT
CATCGCCCAGCACTATCTCGGCAATCGCGTGCCGCCCGTGCTGGTGGTCAGCCACGCGCTGGCCAACCGCGAGCTGATCG
ACCTGCTGGTGGAGCAGGCCGGCCACAAGGTGGCCGTGCTGCGCCAGCCGCAGGGGCAAAAGCGCGCATGGCTGGCGATG
GCCGAGCAGAACGCTCGGCTCGCGCTCGCGCGGCTGCTGTCCGAGCAGGGCTCGCAGCAGGCGCGCACGCGCGCGCTGGC
CGAGGTGCTGGGCTTCGAGGCCGACGATCTCGCGCAACTGCGCATCGAGTGCTTCGACATCAGCCACACGATGGGCGAGG
CGACCCAGGCCTCGTGCGTGGTCTTTCACCACCACAAGATGCAGTCGGGCGAGTATCGCCGCTACAACATCACCGGGATC
ACGCCCGGCGACGACTATGCCGCGATGCGCCAGGTCCTGATGCGCCGCTACGAGAAGATGGTGGAGCAGGCGGGCGAGGC
GGCCGCGGCCGACGCGCAGGCCGGCATCGACGGCGATGCGACGCGCGCCAGCGCCTCGGCCGCGCTGCTGCCGAACATCG
TGCTGATCGACGGCGGCAAGGGGCAGGTGGAGGTCGCGCGGCAGGTGTTCACCGAGCTGGGCCTCGATTGCTCGATGTTG
GTCGGCGTGGCGAAGGGCGAGGGCCGCAAGGTCGGCCTGGAGACGCTGATCTTCGCGGACGGCCGGCCCTCGCTCGAACT
CGGCAAGGAGAGCGCCGCGCTGATGCTGGTTGCGCAGATTCGCGACGAGGCGCACCGCTTCGCCATCACCGGCATGCGCG
CGAAGCGCGCCAAGACGCGCCAGACCTCGCGCCTCGAGGAGCTCGAAGGCGTCGGCGCGAAGCGGCGCCAGCGCCTGCTC
GCGCGTTTCGGCGGCCTGCGCGGCGTGGTGGCCGCGAGCGTCGAGGAACTGGCGAGCGTCGAGGGCATCTCGCACGCGCT
CGCCGAGCAGATCTACCGGCAGCTCCATTGA

Upstream 100 bases:

>100_bases
GTGGCGGAGCGGATCGGAGGCATCGAAGGAATTGGGGCGAATGCACTAAACTGGCGATTCTAAATGACCCGTTCGCGCGC
GCATGGCGCCCGGATTTCGC

Downstream 100 bases:

>100_bases
AACGACGCGCGCCCGCGCGGCTTGTGGCGGTGCGGGCGGCACGGCACAATTGCACATCCTTTATCGGCCCAACCCGACAT
GCCGTTCAATTTCCCGATTT

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MTSPDTSDRPEASGHGGQPAPASQAAAPFEPKPVLAQLPHLPGVYRYYDAAGSVLYVGKARNLKKRVSSYFTKTQLSPRI
AMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDRKNQYFGPFPSAW
AVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIDAADYARDVANASRFLLGRQSEVMKELEQKMHGF
AAELKFEQAAAVRNQMSSLATVLHQQAIEVGSESDVDILAVVAHGGRVCVNLAMVRGGRHLGDKAYFPAHADGALAAGGA
QQAAPDEDAGAIVEDPAALAGAVPDAAAAAAAAAAVVAVETPAAAGSDDPARAPDHAAPAPAAAEAGGARGADEAVPPAE
GPPAVAEADDDAESVAAPIETEVLEAFIAQHYLGNRVPPVLVVSHALANRELIDLLVEQAGHKVAVLRQPQGQKRAWLAM
AEQNARLALARLLSEQGSQQARTRALAEVLGFEADDLAQLRIECFDISHTMGEATQASCVVFHHHKMQSGEYRRYNITGI
TPGDDYAAMRQVLMRRYEKMVEQAGEAAAADAQAGIDGDATRASASAALLPNIVLIDGGKGQVEVARQVFTELGLDCSML
VGVAKGEGRKVGLETLIFADGRPSLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLL
ARFGGLRGVVAASVEELASVEGISHALAEQIYRQLH

Sequences:

>Translated_756_residues
MTSPDTSDRPEASGHGGQPAPASQAAAPFEPKPVLAQLPHLPGVYRYYDAAGSVLYVGKARNLKKRVSSYFTKTQLSPRI
AMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDRKNQYFGPFPSAW
AVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIDAADYARDVANASRFLLGRQSEVMKELEQKMHGF
AAELKFEQAAAVRNQMSSLATVLHQQAIEVGSESDVDILAVVAHGGRVCVNLAMVRGGRHLGDKAYFPAHADGALAAGGA
QQAAPDEDAGAIVEDPAALAGAVPDAAAAAAAAAAVVAVETPAAAGSDDPARAPDHAAPAPAAAEAGGARGADEAVPPAE
GPPAVAEADDDAESVAAPIETEVLEAFIAQHYLGNRVPPVLVVSHALANRELIDLLVEQAGHKVAVLRQPQGQKRAWLAM
AEQNARLALARLLSEQGSQQARTRALAEVLGFEADDLAQLRIECFDISHTMGEATQASCVVFHHHKMQSGEYRRYNITGI
TPGDDYAAMRQVLMRRYEKMVEQAGEAAAADAQAGIDGDATRASASAALLPNIVLIDGGKGQVEVARQVFTELGLDCSML
VGVAKGEGRKVGLETLIFADGRPSLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLL
ARFGGLRGVVAASVEELASVEGISHALAEQIYRQLH
>Mature_755_residues
TSPDTSDRPEASGHGGQPAPASQAAAPFEPKPVLAQLPHLPGVYRYYDAAGSVLYVGKARNLKKRVSSYFTKTQLSPRIA
MMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDRKNQYFGPFPSAWA
VRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIDAADYARDVANASRFLLGRQSEVMKELEQKMHGFA
AELKFEQAAAVRNQMSSLATVLHQQAIEVGSESDVDILAVVAHGGRVCVNLAMVRGGRHLGDKAYFPAHADGALAAGGAQ
QAAPDEDAGAIVEDPAALAGAVPDAAAAAAAAAAVVAVETPAAAGSDDPARAPDHAAPAPAAAEAGGARGADEAVPPAEG
PPAVAEADDDAESVAAPIETEVLEAFIAQHYLGNRVPPVLVVSHALANRELIDLLVEQAGHKVAVLRQPQGQKRAWLAMA
EQNARLALARLLSEQGSQQARTRALAEVLGFEADDLAQLRIECFDISHTMGEATQASCVVFHHHKMQSGEYRRYNITGIT
PGDDYAAMRQVLMRRYEKMVEQAGEAAAADAQAGIDGDATRASASAALLPNIVLIDGGKGQVEVARQVFTELGLDCSMLV
GVAKGEGRKVGLETLIFADGRPSLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLA
RFGGLRGVVAASVEELASVEGISHALAEQIYRQLH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=281, Percent_Identity=45.5516014234875, Blast_Score=278, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 80771; Mature: 80639

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPDTSDRPEASGHGGQPAPASQAAAPFEPKPVLAQLPHLPGVYRYYDAAGSVLYVGKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCEEEECCH
RNLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RDDKSYPYLKLTGHAFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCED
ECCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVFNNRTRPCLLHQIGRCSAPCVGAIDAADYARDVANASRFLLGRQSEVMKELEQKMHGF
HHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AAELKFEQAAAVRNQMSSLATVLHQQAIEVGSESDVDILAVVAHGGRVCVNLAMVRGGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEHHHHHCCCC
LGDKAYFPAHADGALAAGGAQQAAPDEDAGAIVEDPAALAGAVPDAAAAAAAAAAVVAVE
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCHHHHCCCCHHHHHHHHHHHHEEEE
TPAAAGSDDPARAPDHAAPAPAAAEAGGARGADEAVPPAEGPPAVAEADDDAESVAAPIE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHH
TEVLEAFIAQHYLGNRVPPVLVVSHALANRELIDLLVEQAGHKVAVLRQPQGQKRAWLAM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
AEQNARLALARLLSEQGSQQARTRALAEVLGFEADDLAQLRIECFDISHTMGEATQASCV
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEHHHHHCCCCCCEEE
VFHHHKMQSGEYRRYNITGITPGDDYAAMRQVLMRRYEKMVEQAGEAAAADAQAGIDGDA
EEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
TRASASAALLPNIVLIDGGKGQVEVARQVFTELGLDCSMLVGVAKGEGRKVGLETLIFAD
HHHCCCHHHCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEEECCCCCEECCEEEEEEC
GRPSLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLL
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARFGGLRGVVAASVEELASVEGISHALAEQIYRQLH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSPDTSDRPEASGHGGQPAPASQAAAPFEPKPVLAQLPHLPGVYRYYDAAGSVLYVGKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCEEEECCH
RNLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
RDDKSYPYLKLTGHAFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCED
ECCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVFNNRTRPCLLHQIGRCSAPCVGAIDAADYARDVANASRFLLGRQSEVMKELEQKMHGF
HHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AAELKFEQAAAVRNQMSSLATVLHQQAIEVGSESDVDILAVVAHGGRVCVNLAMVRGGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEHHHHHCCCC
LGDKAYFPAHADGALAAGGAQQAAPDEDAGAIVEDPAALAGAVPDAAAAAAAAAAVVAVE
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCHHHHCCCCHHHHHHHHHHHHEEEE
TPAAAGSDDPARAPDHAAPAPAAAEAGGARGADEAVPPAEGPPAVAEADDDAESVAAPIE
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHH
TEVLEAFIAQHYLGNRVPPVLVVSHALANRELIDLLVEQAGHKVAVLRQPQGQKRAWLAM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
AEQNARLALARLLSEQGSQQARTRALAEVLGFEADDLAQLRIECFDISHTMGEATQASCV
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHEEHHHHHCCCCCCEEE
VFHHHKMQSGEYRRYNITGITPGDDYAAMRQVLMRRYEKMVEQAGEAAAADAQAGIDGDA
EEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCC
TRASASAALLPNIVLIDGGKGQVEVARQVFTELGLDCSMLVGVAKGEGRKVGLETLIFAD
HHHCCCHHHCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEEECCCCCEECCEEEEEEC
GRPSLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLL
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARFGGLRGVVAASVEELASVEGISHALAEQIYRQLH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA