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The map label for this gene is pncB [H]

Identifier: 238026584

GI number: 238026584

Start: 1005846

End: 1007045

Strand: Direct

Name: pncB [H]

Synonym: bglu_1g09300

Alternate gene names: 238026584

Gene position: 1005846-1007045 (Clockwise)

Preceding gene: 238026577

Following gene: 238026585

Centisome position: 25.75

GC content: 63.92

Gene sequence:

>1200_bases
ATGATCATTACCTCGCTGCTCGACACCGATCTGTACAAGTTCACGATGATGCAGGTCGTCCTGCATCACTTTCCCGCCGC
CAACGTCGAATACCGCTTTCGTTGCCGCACCCCGGACGTCGATCTCGTTCCCTACATCGACGAGATCCGCGACGAGGTGC
GCGGGCTCTGCCAGCTGCGCTTCAACGACGCCGAACTCGACTATCTGCGGCAGATGCGGTTCATCAAGAGCGATTTCGTC
GATTTCCTCGCGCTGTTCCACCTGAGCGAGAAATACATCGAAATCTCGCCCTCGCCGAAGGGCAACGGCGAGATCGACAT
CGCGATCCGCGGTCCCTGGCTGCACACGATCCTGTTCGAGATCCCGGTGCTGGCGATCGTCAACGAGGTCTATTTCCGCA
ACACGCAGAGCGAGCCCGACTACGGCGAGGGGCGCGGGCGGCTGCGCGAGAAGATGAAGCTGCTCGGCGCGCGGCCCGAG
TTCGCCGACTGCAAGATCGCCGACTACGGCACGCGCCGCCGCTTCTCGAAGGTCTGGCACGAGGAGGTCGCGCTGACGCT
GCGCGACGGGCTGGGCGAGCAGTTCGCGGGCACCAGCAATGTCTATTACGCGATGCGGCACGGCATCACGCCGCTCGGCA
CCATGGCGCACGAGTATCTGCAGGCCTGTCAGGCGCTCGGCCCGCGGCTGCGCGATTCGCAGATCTACGGCCTCGAGATG
TGGGCCAAGGAATATCGCGGCGATCTCGGCATCGCGCTGTCGGACGTCTACGGCATGGACGCGTTCCTGCGCGACTTCGA
CATGTACTTCTGCAAGCTGTTCGACGGCGCGCGCCACGATTCGGGCGACCCGTTCGAGTGGGGCGAGCGGATGATCCGCC
ATTACGAGGCCAACCGCTGCGACCCGCGCACCAAGGTGCTGGTGTTCTCCGACGCGCTCGACATCCCGAAGGTGCTGCAG
CTCTACGAACGCTTCCGCGACCGCTGCAAGCTCGCGTTCGGAGTGGGCACGAACCTGACCAACGATCTCGGCTACCGGCC
GCTGCAGATCGTCATCAAGATGGTCCGCTGCAACGGCCAGCCGGTCGCCAAGCTGTCCGACTCGCCGGGCAAGAGCATGT
GCGACGACAAGGCCTATCTCGCCTACCTGCGCCAGGTGTTCGGCATCGCGCAGCCGGTCGAGGACGAGGCAGGAAAATAA

Upstream 100 bases:

>100_bases
CATGCGGCAGGCAGATCGGGCAGCGCGCGCGCTGCCTGCGGGCTCGGCTCGCTCCGGATTCCGCTACTCCCGCTGATCCC
GTTTTTGGCAGTCTCGAATC

Downstream 100 bases:

>100_bases
GCGGCCGCCACGAGCGGCGCGCCGGGCCGCTCGGCCGGCCGCGTGCGGGGGCGCCGTTATAATCGAGCCCGATCGTTCGT
TATCGTCACGCCCACGAGGA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPDVDLVPYIDEIRDEVRGLCQLRFNDAELDYLRQMRFIKSDFV
DFLALFHLSEKYIEISPSPKGNGEIDIAIRGPWLHTILFEIPVLAIVNEVYFRNTQSEPDYGEGRGRLREKMKLLGARPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGEQFAGTSNVYYAMRHGITPLGTMAHEYLQACQALGPRLRDSQIYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERMIRHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRDRCKLAFGVGTNLTNDLGYRPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEDEAGK

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPDVDLVPYIDEIRDEVRGLCQLRFNDAELDYLRQMRFIKSDFV
DFLALFHLSEKYIEISPSPKGNGEIDIAIRGPWLHTILFEIPVLAIVNEVYFRNTQSEPDYGEGRGRLREKMKLLGARPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGEQFAGTSNVYYAMRHGITPLGTMAHEYLQACQALGPRLRDSQIYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERMIRHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRDRCKLAFGVGTNLTNDLGYRPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEDEAGK
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPDVDLVPYIDEIRDEVRGLCQLRFNDAELDYLRQMRFIKSDFV
DFLALFHLSEKYIEISPSPKGNGEIDIAIRGPWLHTILFEIPVLAIVNEVYFRNTQSEPDYGEGRGRLREKMKLLGARPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGEQFAGTSNVYYAMRHGITPLGTMAHEYLQACQALGPRLRDSQIYGLEM
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERMIRHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRDRCKLAFGVGTNLTNDLGYRPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEDEAGK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=392, Percent_Identity=44.1326530612245, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6324783, Length=401, Percent_Identity=29.1770573566085, Blast_Score=193, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46035; Mature: 46035

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPDVDLVPYIDEIRDEVRGLCQLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEE
FNDAELDYLRQMRFIKSDFVDFLALFHLSEKYIEISPSPKGNGEIDIAIRGPWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQSEPDYGEGRGRLREKMKLLGARPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGEQFAGTSNVYYAMRHGITPLGTMAHEYLQACQALGPRLRDSQIYGLEM
HHHHHHHHHCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERMIRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVLQLYERFRDRCKLAFGVGTNLTNDLGYRPLQIVIKMVRCNGQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEDEAGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPDVDLVPYIDEIRDEVRGLCQLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHEE
FNDAELDYLRQMRFIKSDFVDFLALFHLSEKYIEISPSPKGNGEIDIAIRGPWLHTILFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQSEPDYGEGRGRLREKMKLLGARPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGEQFAGTSNVYYAMRHGITPLGTMAHEYLQACQALGPRLRDSQIYGLEM
HHHHHHHHHCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERMIRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVLQLYERFRDRCKLAFGVGTNLTNDLGYRPLQIVIKMVRCNGQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEDEAGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA