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The map label for this gene is tldD [C]

Identifier: 238025545

GI number: 238025545

Start: 2780073

End: 2781506

Strand: Reverse

Name: tldD [C]

Synonym: bglu_2g22420

Alternate gene names: 238025545

Gene position: 2781506-2780073 (Counterclockwise)

Preceding gene: 238025546

Following gene: 238025544

Centisome position: 98.38

GC content: 73.22

Gene sequence:

>1434_bases
GTGAGTGAGCAACGCTGGGCCGAGGCGGCCCGCAGCCTGCGCGGCGAGGCCGATTTCTGGTCGCTGCGCGTCGTCGACGA
GCGAACCGACGAGCACGCGGTGCGCAACGACGTGGCCGAGCCGTTCAAGCGCAGCCGCGACCGCGGCGCGATGCTGACCG
CCTGGTGCGGCGCGGGCGCCGGCTATGCGGCCACGCCCGACCTGTCGCCGGCCGGCCTGCAGGCCGCGCTCGACGTGGCC
ATCGCGCGCGCGCGCGCCGGCGCGGCCTGGTCGCTGATCGACCATCGCGGCGCCGCGCGCCCCGCGCAGGACGGCTGCTT
CGCCTCGCCCGGCGTCGACGCCGCGCGGCCCACGCGCGCCGAATGGCTCGACCGGCTCGCGCACGAATGCGCCGCCGCCG
CGCTCGACGCGCGCATCGTCGAGCGTACCGCCAGCCTGCTGCTGATCGACACCGATCAGTTCTACCTGACGAGCTACGGC
GTGCGCATCGTGCAGCGCTTCGCGTTCGCCGCGCCCGAGCTGCAGGTGGTGGCGCACCACGACGGCGACACCGAGATGCG
CTCGCTCGGCGGCGGCGGCCTGCTCGCGCAGGGCGGCGCCGAGCTGCTGGCGCGCGCCGGCTTCGACGGCGCCGGCGCGC
GCGTGGCGGCCGAGGCGCTGCAGCTGCTGGCCGCGCCGAACTGCCCGCGCGGCCCGCGCGACCTGCTGCTGATGCCCGAC
CAGATGATGCTGCAGATCCACGAATCGATCGGCCATCCGCTCGAACTCGATCGCATCCTCGGCGACGAGCGCAACTTCGC
CGGCTCGAGCTTCGTGAAGCCCGAGATGTTCGGCAGCTACCGCTACGGCTCGCCGCTGCTCAACGTCACGTTCGCGCCCG
ACGTGGCCGGCGAGGCCGCCTCGTATGCCTACGACGACGACGGCACGCGCGCCGAGCGCGCCTACCTGATCCGTGACGGC
ATACTCGAGCGGCCGCTCGGCGGGGCGCTGTCGCAGCGGCGCGCCGGCCTGCCCGGCGTGGCCAACACGCGCGCGTCGAG
CTGGAACCGCCCGCCGATCGACCGCATGGCGAATCTCAACCTCGAACCCGGCGATGCGTCGCTCGACGCGCTGATCGCCG
GCACCGAGCACGGCATCCTGATGCGCACCAACACTTCCTGGTCGATCGACGACCAGCGCAACAAGTTCCAGTTCGGCTGC
GAATATGGCCAGCTGATCGAGAACGGCCGGCTCACGCAGGTGGTGCGCAAGCCCAATTATCGCGGCGTCTCGGCCGGCTT
CTGGCGCAGCCTGCGCGCGGTGGGCGACGCGAGCACCTTCGGCGTGCACGGCACGCCCTACTGCGGCAAGGGCGAGCCGG
CGCAGATCATTCGCGTCGGGCATGCCTCGCCCGCCTGCGTGTTCGCCGACGTCGACGTGTTCGGAGGCGCCTGA

Upstream 100 bases:

>100_bases
GCGACGCGCTCGACGTGCTGAACGCGCCGTCGCACGCCTATACGAGGGCGCTGCTCGCGTCGTCGCTGCTCGCGGCGCCG
CGCGCGGCCGAGGAGAGCGA

Downstream 100 bases:

>100_bases
TGGACGAATCGCTGATGGGCGCGGTGCGCGCCGCCCGGCGTGCCGGCTCGATCGACTGGCACGGCCACTTCATGCGGCTC
GCCGACGAGGCCGACGCGCG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSEQRWAEAARSLRGEADFWSLRVVDERTDEHAVRNDVAEPFKRSRDRGAMLTAWCGAGAGYAATPDLSPAGLQAALDVA
IARARAGAAWSLIDHRGAARPAQDGCFASPGVDAARPTRAEWLDRLAHECAAAALDARIVERTASLLLIDTDQFYLTSYG
VRIVQRFAFAAPELQVVAHHDGDTEMRSLGGGGLLAQGGAELLARAGFDGAGARVAAEALQLLAAPNCPRGPRDLLLMPD
QMMLQIHESIGHPLELDRILGDERNFAGSSFVKPEMFGSYRYGSPLLNVTFAPDVAGEAASYAYDDDGTRAERAYLIRDG
ILERPLGGALSQRRAGLPGVANTRASSWNRPPIDRMANLNLEPGDASLDALIAGTEHGILMRTNTSWSIDDQRNKFQFGC
EYGQLIENGRLTQVVRKPNYRGVSAGFWRSLRAVGDASTFGVHGTPYCGKGEPAQIIRVGHASPACVFADVDVFGGA

Sequences:

>Translated_477_residues
MSEQRWAEAARSLRGEADFWSLRVVDERTDEHAVRNDVAEPFKRSRDRGAMLTAWCGAGAGYAATPDLSPAGLQAALDVA
IARARAGAAWSLIDHRGAARPAQDGCFASPGVDAARPTRAEWLDRLAHECAAAALDARIVERTASLLLIDTDQFYLTSYG
VRIVQRFAFAAPELQVVAHHDGDTEMRSLGGGGLLAQGGAELLARAGFDGAGARVAAEALQLLAAPNCPRGPRDLLLMPD
QMMLQIHESIGHPLELDRILGDERNFAGSSFVKPEMFGSYRYGSPLLNVTFAPDVAGEAASYAYDDDGTRAERAYLIRDG
ILERPLGGALSQRRAGLPGVANTRASSWNRPPIDRMANLNLEPGDASLDALIAGTEHGILMRTNTSWSIDDQRNKFQFGC
EYGQLIENGRLTQVVRKPNYRGVSAGFWRSLRAVGDASTFGVHGTPYCGKGEPAQIIRVGHASPACVFADVDVFGGA
>Mature_476_residues
SEQRWAEAARSLRGEADFWSLRVVDERTDEHAVRNDVAEPFKRSRDRGAMLTAWCGAGAGYAATPDLSPAGLQAALDVAI
ARARAGAAWSLIDHRGAARPAQDGCFASPGVDAARPTRAEWLDRLAHECAAAALDARIVERTASLLLIDTDQFYLTSYGV
RIVQRFAFAAPELQVVAHHDGDTEMRSLGGGGLLAQGGAELLARAGFDGAGARVAAEALQLLAAPNCPRGPRDLLLMPDQ
MMLQIHESIGHPLELDRILGDERNFAGSSFVKPEMFGSYRYGSPLLNVTFAPDVAGEAASYAYDDDGTRAERAYLIRDGI
LERPLGGALSQRRAGLPGVANTRASSWNRPPIDRMANLNLEPGDASLDALIAGTEHGILMRTNTSWSIDDQRNKFQFGCE
YGQLIENGRLTQVVRKPNYRGVSAGFWRSLRAVGDASTFGVHGTPYCGKGEPAQIIRVGHASPACVFADVDVFGGA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=259, Percent_Identity=27.7992277992278, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51229; Mature: 51098

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQRWAEAARSLRGEADFWSLRVVDERTDEHAVRNDVAEPFKRSRDRGAMLTAWCGAGA
CCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GYAATPDLSPAGLQAALDVAIARARAGAAWSLIDHRGAARPAQDGCFASPGVDAARPTRA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
EWLDRLAHECAAAALDARIVERTASLLLIDTDQFYLTSYGVRIVQRFAFAAPELQVVAHH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
DGDTEMRSLGGGGLLAQGGAELLARAGFDGAGARVAAEALQLLAAPNCPRGPRDLLLMPD
CCCHHHHHCCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCH
QMMLQIHESIGHPLELDRILGDERNFAGSSFVKPEMFGSYRYGSPLLNVTFAPDVAGEAA
HHHHHHHHHHCCCEEHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCC
SYAYDDDGTRAERAYLIRDGILERPLGGALSQRRAGLPGVANTRASSWNRPPIDRMANLN
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCC
LEPGDASLDALIAGTEHGILMRTNTSWSIDDQRNKFQFGCEYGQLIENGRLTQVVRKPNY
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHHCCCC
RGVSAGFWRSLRAVGDASTFGVHGTPYCGKGEPAQIIRVGHASPACVFADVDVFGGA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECHHCCCC
>Mature Secondary Structure 
SEQRWAEAARSLRGEADFWSLRVVDERTDEHAVRNDVAEPFKRSRDRGAMLTAWCGAGA
CHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GYAATPDLSPAGLQAALDVAIARARAGAAWSLIDHRGAARPAQDGCFASPGVDAARPTRA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
EWLDRLAHECAAAALDARIVERTASLLLIDTDQFYLTSYGVRIVQRFAFAAPELQVVAHH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
DGDTEMRSLGGGGLLAQGGAELLARAGFDGAGARVAAEALQLLAAPNCPRGPRDLLLMPD
CCCHHHHHCCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCH
QMMLQIHESIGHPLELDRILGDERNFAGSSFVKPEMFGSYRYGSPLLNVTFAPDVAGEAA
HHHHHHHHHHCCCEEHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCC
SYAYDDDGTRAERAYLIRDGILERPLGGALSQRRAGLPGVANTRASSWNRPPIDRMANLN
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCC
LEPGDASLDALIAGTEHGILMRTNTSWSIDDQRNKFQFGCEYGQLIENGRLTQVVRKPNY
CCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHHCCCC
RGVSAGFWRSLRAVGDASTFGVHGTPYCGKGEPAQIIRVGHASPACVFADVDVFGGA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]