| Definition | Burkholderia glumae BGR1 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_012721 |
| Length | 2,827,333 |
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The map label for this gene is mrcA [H]
Identifier: 238025540
GI number: 238025540
Start: 2771647
End: 2774289
Strand: Reverse
Name: mrcA [H]
Synonym: bglu_2g22370
Alternate gene names: 238025540
Gene position: 2774289-2771647 (Counterclockwise)
Preceding gene: 238025541
Following gene: 238025538
Centisome position: 98.12
GC content: 73.17
Gene sequence:
>2643_bases GTGAATCGTCGTTTCGTGTCCCGTCTGCTTGCCCGTGCCGCCGCGTGGCGGGCCGCCGTCCAGCCCGTCGTGGCCGCCGC CGTCGCCCGCGCGCGGCCGCGCGCGGCGCATGTGCTTGCCGCGCTGTGGGCCCGGCTGCGGCACCCGACGCGCCGCGGCG TGCTGATCGCGCTGGCCGTGCCGCCGGCGCTGCTGGTGCTCTACGTGCTGGTGCTGATCCCGTTCACGCCGAGCATCGGC GACATCCGCAAGGCGCGCGTGGACGCGCCGGCCCAGGTGATGTCGGCCGACGGCAGGCTGCTCGCCGAGTTCAAGCCGTC CAACCGCGAATGGGTCGCGCTGGCCGACATCTCGCCGCACATGGTGGACGCGCTGATCGCCACCGAGGACCACCGCTTCT ACCAGCACCACGGCCTCGACTGGCGCCGCACCGCCGGCGCCGCGCTGCACACCTTCTCGGGCGACCGGCAGGGCGGCTCC ACCATCACCCAGCAGCTCGCTCGCAACCTCTATCCCGACCAGATCGGCCGCGCGCCCACGCTCACGCGCAAGCTCAAGGA AGCGATCACGGCGCTGAAGATCGAGGCCGTCTACAACAAGCAGCAGATCCTCGAGACCTACCTGAACACGGTCCCGTTCC TCTACAACGCCTACGGCGTGGAGATGGCCGCGCGCACCTACTTCGACAAGTCGGCCGACCAGCTCGACGTGCTCGACAGC GCCACGCTGGTGGGCATGCTCAAGGGCAACAGCTACTACAACCCGGTGATCAACCCCGAGCGCGCGCTGCAGCGGCGCAA CACCGTGCTCGGGCAGATGGTGAAGTACGGCAAGCTCTCGCCCGCGCAGTTCGCGGTGCTGCAAAGGAAGCCGCTGCGCA TCGACTTCGAGCGCCAGAAGGAGCCGCCCGGCCCGGCGCCGCATTTCGCGCAGCAGCTGAAGAAATGGCTGATCGGCTGG GCCGACCGCAACGACTACAACATCTATTCCGACGGCCTCGTCGTGCGCACCACGATCGATTCGCGGCTGCAGGCGATGGC CACCCAGGCGCTCAAGCTGCAGGCCAACCAGCTGCAGGCCATCGCCAACGGCGCCTGGAACGCCGGCAGCGGCTGCGCGC CCGGCAACGCGCTGTTCAAGACCTTCATGCGCGAGTCGCGCGAATACAAGGCCGCGCGCGACGGCGGCGCCGACGACGGC ACGGCGCTCAAGACGCTCGGCCGCGATCGCGCCTTCCTGCGCGGGCTCTGCAAGGCCAAGGCGGACCTGCAGGCCGGCTT CGTCGCGATCGACCCGCGCGACGGCGCGATCCGCGCCTGGGTGGGCAGCCGCGACTTCGCCACCGAGCCGTTCGACCACG TGCAGCAGGCGCGCCGCCAGCCGGGCTCGACCTTCAAGCCGTTCGTCTACGGCGCCGCGTTCGCCGACGGCGCGAAGCCC ACCGACACCTTCATCGACCAGCCGGTCGAGATTCCGCTCAAGGGCGGCGAGATCTGGCGCCCGGACGACGCCGAGCCGCC CACCGGCAAGCCGATGACGCTGGCCGACGCGCTCGCCTACTCGCGCAACCGCATCACCGCGCAGCTGATGCAGCAGGTCG GGCCGGCCAAGGTCGCGCGACTCGCGCGCGAGATGGGCGTGCGCGACAGCACGCTGGAGGCGGTGCCCTCGCTCGCGCTC GGCACCAGCCCGGTCACGCTCAAGGAGATGGTGTCGGGCTACGCGACCATCGCCAACCTCGGCAGCTACGTCGAACCGCG CATGGTCACGCGCATCGAGGATCGCGCCGGCCGTGTGCTGGCCGAATTCGCGCCGGCGCCGCCCGAGCGCGCGCTCGCGC CCGGCGCGGCGCGCACGCTGGTGGCGACCCTGCGCGGCGTGATCAATCGCGGCACCGGCACGGCGATCCGCTCGCGCTTC GGGATTCGCGCCGACGTGGCCGGCAAGACCGGCACCACGCAGGGCGACACCGACGGCTGGTTCATCCTGATCCAGCCGCA ACTGGTGGCGGGCGCCTGGGTGGGCTTCGACGACGGGCGCGTGACGCTCGGCGACACCTGGGGGCAGGGCGCGCGCAGCG CGCTGCCGATGGTCGGTGACTTCTACCAGCGCGCGTTCCGGGCCAGGTTGATCGATGCGCGCGCGAAGTTCGACACCGAC ACGCCGCCGGGCTTCTTCGACACGCTGCGCGGCAAGCTCGACGACTGGATCGCCTATCTGTTCCCGGCCCGGTCCGCGCC ACCGGCCGCGCCGGCCGCGCCGCGCGGACCGGCGCTGGCGCCCGCGCCCGCGCCGGCACCGGACGCGGCGCAGCAGGCGG CCAGCGCCGCGAGCGCGGCCAGTGCGGCGAGCGCGGCGAGCGCGGCGGCGCAGGCCGAGGCGGCGTCCGATCCGCTCGGC GCGTTCCTGAGCGGCGCATCCGGCGCGGCGGGAACGGCCGGCGCGCGGCGGGCGCTCCCGGCATCGGGCGTCGATACCTT CAGCGCGTCGGCACCGCCGCTGCTGCCGACGGCGCCGGTGAACGACGGCCAGGGCGGCAACCAGGGCGGCACGGGCAACG GCCTGCCGGCCGAGGCGCCGGCCGAGTCGCCGACGCCGACGCCCGACTCGCCCTCCGCGGGCGCCGGCGGCACCGTCCAA TAG
Upstream 100 bases:
>100_bases TCGCCTACCGGCTGGTGGCCGGGCTGGGCCGCGCGTCGCCCGCCGGGCGCCGCCGCCGGCTTTGATACGATGCACGCTTT CGGCTCCTCGAGTGTTTCGC
Downstream 100 bases:
>100_bases GACCCGCCGGCGCGCGAGCCGGCCTATCAGGGCGCGACGCCGTCGATTGAAAAATATGCCGGGCGGTGGCAAGGCGGCGC GCCGGGCGGGTGACCGGCGC
Product: membrane carboxypeptidase/penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 880; Mature: 880
Protein sequence:
>880_residues MNRRFVSRLLARAAAWRAAVQPVVAAAVARARPRAAHVLAALWARLRHPTRRGVLIALAVPPALLVLYVLVLIPFTPSIG DIRKARVDAPAQVMSADGRLLAEFKPSNREWVALADISPHMVDALIATEDHRFYQHHGLDWRRTAGAALHTFSGDRQGGS TITQQLARNLYPDQIGRAPTLTRKLKEAITALKIEAVYNKQQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDVLDS ATLVGMLKGNSYYNPVINPERALQRRNTVLGQMVKYGKLSPAQFAVLQRKPLRIDFERQKEPPGPAPHFAQQLKKWLIGW ADRNDYNIYSDGLVVRTTIDSRLQAMATQALKLQANQLQAIANGAWNAGSGCAPGNALFKTFMRESREYKAARDGGADDG TALKTLGRDRAFLRGLCKAKADLQAGFVAIDPRDGAIRAWVGSRDFATEPFDHVQQARRQPGSTFKPFVYGAAFADGAKP TDTFIDQPVEIPLKGGEIWRPDDAEPPTGKPMTLADALAYSRNRITAQLMQQVGPAKVARLAREMGVRDSTLEAVPSLAL GTSPVTLKEMVSGYATIANLGSYVEPRMVTRIEDRAGRVLAEFAPAPPERALAPGAARTLVATLRGVINRGTGTAIRSRF GIRADVAGKTGTTQGDTDGWFILIQPQLVAGAWVGFDDGRVTLGDTWGQGARSALPMVGDFYQRAFRARLIDARAKFDTD TPPGFFDTLRGKLDDWIAYLFPARSAPPAAPAAPRGPALAPAPAPAPDAAQQAASAASAASAASAASAAAQAEAASDPLG AFLSGASGAAGTAGARRALPASGVDTFSASAPPLLPTAPVNDGQGGNQGGTGNGLPAEAPAESPTPTPDSPSAGAGGTVQ
Sequences:
>Translated_880_residues MNRRFVSRLLARAAAWRAAVQPVVAAAVARARPRAAHVLAALWARLRHPTRRGVLIALAVPPALLVLYVLVLIPFTPSIG DIRKARVDAPAQVMSADGRLLAEFKPSNREWVALADISPHMVDALIATEDHRFYQHHGLDWRRTAGAALHTFSGDRQGGS TITQQLARNLYPDQIGRAPTLTRKLKEAITALKIEAVYNKQQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDVLDS ATLVGMLKGNSYYNPVINPERALQRRNTVLGQMVKYGKLSPAQFAVLQRKPLRIDFERQKEPPGPAPHFAQQLKKWLIGW ADRNDYNIYSDGLVVRTTIDSRLQAMATQALKLQANQLQAIANGAWNAGSGCAPGNALFKTFMRESREYKAARDGGADDG TALKTLGRDRAFLRGLCKAKADLQAGFVAIDPRDGAIRAWVGSRDFATEPFDHVQQARRQPGSTFKPFVYGAAFADGAKP TDTFIDQPVEIPLKGGEIWRPDDAEPPTGKPMTLADALAYSRNRITAQLMQQVGPAKVARLAREMGVRDSTLEAVPSLAL GTSPVTLKEMVSGYATIANLGSYVEPRMVTRIEDRAGRVLAEFAPAPPERALAPGAARTLVATLRGVINRGTGTAIRSRF GIRADVAGKTGTTQGDTDGWFILIQPQLVAGAWVGFDDGRVTLGDTWGQGARSALPMVGDFYQRAFRARLIDARAKFDTD TPPGFFDTLRGKLDDWIAYLFPARSAPPAAPAAPRGPALAPAPAPAPDAAQQAASAASAASAASAASAAAQAEAASDPLG AFLSGASGAAGTAGARRALPASGVDTFSASAPPLLPTAPVNDGQGGNQGGTGNGLPAEAPAESPTPTPDSPSAGAGGTVQ >Mature_880_residues MNRRFVSRLLARAAAWRAAVQPVVAAAVARARPRAAHVLAALWARLRHPTRRGVLIALAVPPALLVLYVLVLIPFTPSIG DIRKARVDAPAQVMSADGRLLAEFKPSNREWVALADISPHMVDALIATEDHRFYQHHGLDWRRTAGAALHTFSGDRQGGS TITQQLARNLYPDQIGRAPTLTRKLKEAITALKIEAVYNKQQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDVLDS ATLVGMLKGNSYYNPVINPERALQRRNTVLGQMVKYGKLSPAQFAVLQRKPLRIDFERQKEPPGPAPHFAQQLKKWLIGW ADRNDYNIYSDGLVVRTTIDSRLQAMATQALKLQANQLQAIANGAWNAGSGCAPGNALFKTFMRESREYKAARDGGADDG TALKTLGRDRAFLRGLCKAKADLQAGFVAIDPRDGAIRAWVGSRDFATEPFDHVQQARRQPGSTFKPFVYGAAFADGAKP TDTFIDQPVEIPLKGGEIWRPDDAEPPTGKPMTLADALAYSRNRITAQLMQQVGPAKVARLAREMGVRDSTLEAVPSLAL GTSPVTLKEMVSGYATIANLGSYVEPRMVTRIEDRAGRVLAEFAPAPPERALAPGAARTLVATLRGVINRGTGTAIRSRF GIRADVAGKTGTTQGDTDGWFILIQPQLVAGAWVGFDDGRVTLGDTWGQGARSALPMVGDFYQRAFRARLIDARAKFDTD TPPGFFDTLRGKLDDWIAYLFPARSAPPAAPAAPRGPALAPAPAPAPDAAQQAASAASAASAASAASAAAQAEAASDPLG AFLSGASGAAGTAGARRALPASGVDTFSASAPPLLPTAPVNDGQGGNQGGTGNGLPAEAPAESPTPTPDSPSAGAGGTVQ
Specific function: Cell Wall Formation. Synthesis Of Cross-Linked Peptidoglycan From The Lipid Intermediates. The Enzyme Has A Penicillin-Insensitive Transglycosylase N-Terminal Domain (Formation Of Linear Glycan Strands) And A Penicillin-Sensitive Transpeptidase C-Terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=593, Percent_Identity=31.8718381112985, Blast_Score=258, Evalue=1e-69, Organism=Escherichia coli, GI1786343, Length=603, Percent_Identity=29.0215588723051, Blast_Score=183, Evalue=5e-47, Organism=Escherichia coli, GI1788867, Length=270, Percent_Identity=31.8518518518519, Blast_Score=100, Evalue=3e-22, Organism=Escherichia coli, GI1789601, Length=174, Percent_Identity=35.632183908046, Blast_Score=86, Evalue=1e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 93652; Mature: 93652
Theoretical pI: Translated: 10.27; Mature: 10.27
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRRFVSRLLARAAAWRAAVQPVVAAAVARARPRAAHVLAALWARLRHPTRRGVLIALAV CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC PPALLVLYVLVLIPFTPSIGDIRKARVDAPAQVMSADGRLLAEFKPSNREWVALADISPH CHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCEEEEECCCHH MVDALIATEDHRFYQHHGLDWRRTAGAALHTFSGDRQGGSTITQQLARNLYPDQIGRAPT HHHHHHHCCCHHHHHHCCCCHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCHHHCCCCHH LTRKLKEAITALKIEAVYNKQQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDVLDS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH ATLVGMLKGNSYYNPVINPERALQRRNTVLGQMVKYGKLSPAQFAVLQRKPLRIDFERQK HHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEECHHHCC EPPGPAPHFAQQLKKWLIGWADRNDYNIYSDGLVVRTTIDSRLQAMATQALKLQANQLQA CCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHH IANGAWNAGSGCAPGNALFKTFMRESREYKAARDGGADDGTALKTLGRDRAFLRGLCKAK HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHH ADLQAGFVAIDPRDGAIRAWVGSRDFATEPFDHVQQARRQPGSTFKPFVYGAAFADGAKP HHHCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHEEHHHCCCCCC TDTFIDQPVEIPLKGGEIWRPDDAEPPTGKPMTLADALAYSRNRITAQLMQQVGPAKVAR CHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH LAREMGVRDSTLEAVPSLALGTSPVTLKEMVSGYATIANLGSYVEPRMVTRIEDRAGRVL HHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH AEFAPAPPERALAPGAARTLVATLRGVINRGTGTAIRSRFGIRADVAGKTGTTQGDTDGW HHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCCCCCCCE FILIQPQLVAGAWVGFDDGRVTLGDTWGQGARSALPMVGDFYQRAFRARLIDARAKFDTD EEEEECCEEEEEEEECCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC TPPGFFDTLRGKLDDWIAYLFPARSAPPAAPAAPRGPALAPAPAPAPDAAQQAASAASAA CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH SAASAASAAAQAEAASDPLGAFLSGASGAAGTAGARRALPASGVDTFSASAPPLLPTAPV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC NDGQGGNQGGTGNGLPAEAPAESPTPTPDSPSAGAGGTVQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MNRRFVSRLLARAAAWRAAVQPVVAAAVARARPRAAHVLAALWARLRHPTRRGVLIALAV CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC PPALLVLYVLVLIPFTPSIGDIRKARVDAPAQVMSADGRLLAEFKPSNREWVALADISPH CHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCEEEEECCCHH MVDALIATEDHRFYQHHGLDWRRTAGAALHTFSGDRQGGSTITQQLARNLYPDQIGRAPT HHHHHHHCCCHHHHHHCCCCHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCHHHCCCCHH LTRKLKEAITALKIEAVYNKQQILETYLNTVPFLYNAYGVEMAARTYFDKSADQLDVLDS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH ATLVGMLKGNSYYNPVINPERALQRRNTVLGQMVKYGKLSPAQFAVLQRKPLRIDFERQK HHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEECHHHCC EPPGPAPHFAQQLKKWLIGWADRNDYNIYSDGLVVRTTIDSRLQAMATQALKLQANQLQA CCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHH IANGAWNAGSGCAPGNALFKTFMRESREYKAARDGGADDGTALKTLGRDRAFLRGLCKAK HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHH ADLQAGFVAIDPRDGAIRAWVGSRDFATEPFDHVQQARRQPGSTFKPFVYGAAFADGAKP HHHCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHEEHHHCCCCCC TDTFIDQPVEIPLKGGEIWRPDDAEPPTGKPMTLADALAYSRNRITAQLMQQVGPAKVAR CHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH LAREMGVRDSTLEAVPSLALGTSPVTLKEMVSGYATIANLGSYVEPRMVTRIEDRAGRVL HHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH AEFAPAPPERALAPGAARTLVATLRGVINRGTGTAIRSRFGIRADVAGKTGTTQGDTDGW HHHCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCCCCCCCE FILIQPQLVAGAWVGFDDGRVTLGDTWGQGARSALPMVGDFYQRAFRARLIDARAKFDTD EEEEECCEEEEEEEECCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC TPPGFFDTLRGKLDDWIAYLFPARSAPPAAPAAPRGPALAPAPAPAPDAAQQAASAASAA CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH SAASAASAAAQAEAASDPLGAFLSGASGAAGTAGARRALPASGVDTFSASAPPLLPTAPV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC NDGQGGNQGGTGNGLPAEAPAESPTPTPDSPSAGAGGTVQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]