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The map label for this gene is thcR [H]

Identifier: 238025430

GI number: 238025430

Start: 2628406

End: 2629410

Strand: Reverse

Name: thcR [H]

Synonym: bglu_2g21200

Alternate gene names: 238025430

Gene position: 2629410-2628406 (Counterclockwise)

Preceding gene: 238025431

Following gene: 238025429

Centisome position: 93.0

GC content: 67.66

Gene sequence:

>1005_bases
ATGCATACGTCCGCCGTCAATGAGGCCCGCGGTATCGACGCGCTGCGTCACGACCTCGAAGGCGCGCGGGACTGGATGGC
GTCGATTTGCGGCCCGCACGCGCTGCGGGCCCGGAGCCCGGACAAGCTGCAGTTCCATCATTCGGGCACGGTGATGCGGT
CGATGGCGAGCACCTTGGGGTACGTCGAGTACGGCACCGACGTCACCGTCTCGGTGGACAAGGCGGCGCCGCTCAACTGC
TACAGCGTGAGCTTGCCGCTCAGCGGCTACCAGGAGCTGTCCGCCCAGGGACGGCGGTGGCTGTCGGACCAGGACCACGG
CATCGTGCTGTCGCCGCACGAGCGGCAGGATCTGGCGATCACGGGCAATTGCCGCAAGATCATCGTGGCCATTCCGGGCC
AGGCGCTGCGCCAGGTGCTCGAAGGGCTGCTGCAACGGCCGCTGCAGGCGCCTTTGACCTTCGAACCCCGGATGAGTGCC
GCCGAGGGGGACCAGGCCGCCTGGTGGCGCATGGTCAGATTCCTGCTGGCCGAGCTGGAGCGGGCCGCGCCGCTGCTGGA
GCACCAGCAGATGGCGGAGAACCTCGAGCAGGCCCTGATCAAGGGGCTGCTGCTCTGTCAGCCGCACAACTACTCGCCGG
CGCTCGCCGGCCTGGTGCAGCCGGCCTGCCCGCACTATCTGTTGCGCGCTAGGCAGTTTATCCACGACAACGCCCGCGAG
GATATCGCGCTCGAGGACATCGAGCAGGCGGCCGGCGTGTCGCGCTACAAGCTGTTCGAGGGCTTCCGGCATCACTTCGG
TCAGGCGCCCATGGCCTATCTGAAGGGGCACCGGCTCGAAGCGGTGCGGCGGGAGATGCTCGGCGACCGCTCGGAACGCA
ATGTTTCGGCGATCGCGATGAACTGGGGCTTCTCGCATCTTGGCCGCTTTTCCAGCGACTACAAGCAGCGCTTCGGCGAA
ACCCCGTCGCAAACCCTCAAGCGCGCGACGCGGCGAGCCGCGTGA

Upstream 100 bases:

>100_bases
AACAGGCTGCATAAGCTTGCAGGTCAGGGTGTCTTAGTATTTTTTCCGGGCACGGTGTGGTTTACCATCGAACCACGACT
AACCGCCCGGTGACACCCCC

Downstream 100 bases:

>100_bases
GCGGCCGCCGCCCGCCGTTCGCCGTCACCGCCGTTTGCCGTTCGCCATTTCCCTACGCCTGATTTCACGTTCGAGCCCGG
CCGCTCCGGGGGCGCCGCAA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHTSAVNEARGIDALRHDLEGARDWMASICGPHALRARSPDKLQFHHSGTVMRSMASTLGYVEYGTDVTVSVDKAAPLNC
YSVSLPLSGYQELSAQGRRWLSDQDHGIVLSPHERQDLAITGNCRKIIVAIPGQALRQVLEGLLQRPLQAPLTFEPRMSA
AEGDQAAWWRMVRFLLAELERAAPLLEHQQMAENLEQALIKGLLLCQPHNYSPALAGLVQPACPHYLLRARQFIHDNARE
DIALEDIEQAAGVSRYKLFEGFRHHFGQAPMAYLKGHRLEAVRREMLGDRSERNVSAIAMNWGFSHLGRFSSDYKQRFGE
TPSQTLKRATRRAA

Sequences:

>Translated_334_residues
MHTSAVNEARGIDALRHDLEGARDWMASICGPHALRARSPDKLQFHHSGTVMRSMASTLGYVEYGTDVTVSVDKAAPLNC
YSVSLPLSGYQELSAQGRRWLSDQDHGIVLSPHERQDLAITGNCRKIIVAIPGQALRQVLEGLLQRPLQAPLTFEPRMSA
AEGDQAAWWRMVRFLLAELERAAPLLEHQQMAENLEQALIKGLLLCQPHNYSPALAGLVQPACPHYLLRARQFIHDNARE
DIALEDIEQAAGVSRYKLFEGFRHHFGQAPMAYLKGHRLEAVRREMLGDRSERNVSAIAMNWGFSHLGRFSSDYKQRFGE
TPSQTLKRATRRAA
>Mature_334_residues
MHTSAVNEARGIDALRHDLEGARDWMASICGPHALRARSPDKLQFHHSGTVMRSMASTLGYVEYGTDVTVSVDKAAPLNC
YSVSLPLSGYQELSAQGRRWLSDQDHGIVLSPHERQDLAITGNCRKIIVAIPGQALRQVLEGLLQRPLQAPLTFEPRMSA
AEGDQAAWWRMVRFLLAELERAAPLLEHQQMAENLEQALIKGLLLCQPHNYSPALAGLVQPACPHYLLRARQFIHDNARE
DIALEDIEQAAGVSRYKLFEGFRHHFGQAPMAYLKGHRLEAVRREMLGDRSERNVSAIAMNWGFSHLGRFSSDYKQRFGE
TPSQTLKRATRRAA

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=188, Percent_Identity=32.4468085106383, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37449; Mature: 37449

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSAVNEARGIDALRHDLEGARDWMASICGPHALRARSPDKLQFHHSGTVMRSMASTLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHH
YVEYGTDVTVSVDKAAPLNCYSVSLPLSGYQELSAQGRRWLSDQDHGIVLSPHERQDLAI
HHEECCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEE
TGNCRKIIVAIPGQALRQVLEGLLQRPLQAPLTFEPRMSAAEGDQAAWWRMVRFLLAELE
ECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAAPLLEHQQMAENLEQALIKGLLLCQPHNYSPALAGLVQPACPHYLLRARQFIHDNARE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
DIALEDIEQAAGVSRYKLFEGFRHHFGQAPMAYLKGHRLEAVRREMLGDRSERNVSAIAM
CHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEEE
NWGFSHLGRFSSDYKQRFGETPSQTLKRATRRAA
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHTSAVNEARGIDALRHDLEGARDWMASICGPHALRARSPDKLQFHHSGTVMRSMASTLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHH
YVEYGTDVTVSVDKAAPLNCYSVSLPLSGYQELSAQGRRWLSDQDHGIVLSPHERQDLAI
HHEECCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEE
TGNCRKIIVAIPGQALRQVLEGLLQRPLQAPLTFEPRMSAAEGDQAAWWRMVRFLLAELE
ECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RAAPLLEHQQMAENLEQALIKGLLLCQPHNYSPALAGLVQPACPHYLLRARQFIHDNARE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
DIALEDIEQAAGVSRYKLFEGFRHHFGQAPMAYLKGHRLEAVRREMLGDRSERNVSAIAM
CHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEEE
NWGFSHLGRFSSDYKQRFGETPSQTLKRATRRAA
ECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]