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The map label for this gene is tlpC [H]

Identifier: 238025321

GI number: 238025321

Start: 2478806

End: 2480719

Strand: Reverse

Name: tlpC [H]

Synonym: bglu_2g19950

Alternate gene names: 238025321

Gene position: 2480719-2478806 (Counterclockwise)

Preceding gene: 238025333

Following gene: 238025320

Centisome position: 87.74

GC content: 66.46

Gene sequence:

>1914_bases
ATGGCACTCGTGAGGCACTCCCAGAAAACAGCTGACGGCGCATCCGACGGCCCTCGCGCGGTGGGCTCCACCCGCGACGC
CGAGGCCCAGCGCAAGCGCGCGCGTACTCTGGCCAAGCAGCAGCAGGCGGCCGAACGGATCGCAGCCGCCACGACGCAAT
TGGCGTCCGGCATCAACGAGGCCGCCTCGGCGGCCGAGGAGCTCAAGCGCGCGGCCGACCAGATCGCCACCGGCGCCGAG
GAGGCCAGTGGCGCGGCTCAGGAATCGCTTACCGCGTTCAAGCTGATGGAGGACGCGATCGCGCGCCAACGGCAAAGCGC
GGATACGAGCCAGGCGCGGGTGGAAACCACGCAGATCCTGATCGCGCGCACCACTGCCGATGTTGGCGGCCTGGTCACCA
ACGTCGGCTTCGTCGCGCAACGGCAGGCCGCTTCGGTGCAGCGGGTGCAGGAACTGGAGCAGCAGGCCGCCAACATCGGC
GACATCGTCAAGGCGGTCGTGCGCATCGCCGATCAGACCAACCTGCTCGCGCTCAACGCCGCGATCGAGGCGGCGCGCGC
CGGCAAGCACGGCAAGGGCTTTGCGGTAGTGGCCGACGAAGTGCGCACGCTGGCCGAGACCTCCGAGAAGAGCGCCAAGC
AGATCCAGGATCTGGTCGGACAAATCCAGCAGGAAGTGAAGATCGTTGCCGAAGGCATCAATGCTTCGGCGCGCAGCATT
GAAACGGAGGTGGCGAAAGGCGCCGCGATTACGGAACAGCTCGAGCAGATCCGCAAGGACACCATCGAGATCATGACCGG
CGCCACGGAGATCGCCAATGGCGCGCAGCAGTCCGCCGCCGCCACGCAGCAGGCGCTCAAGGGCTCGGAAAGCATCGCCG
CGGCAGCCGAAGAACAATCGGCGGCCGCCGAGGAGTCGGCCAAGACGGTGAGCGAGCAGGCGCGGGCGCTGAACGAATGC
GAGCAGACCACGCAGGCGTTGTCGGAATTGGCCGAAGATCTGAAGAGTTCCACCGACGTGGCCAAGAGCGCGGAGGAAGT
GGCCTCGGCTGCCGAGGAACTGTCTTCCGCGGTGCAGGAAATCAACCGCTCCAGCGCTCAGATCCTCGTCGCGATCGACC
AGATCCGCAAAGGCGCGCAGGTCCAGGCCCGCGCCATCGAGGACTCCGTGGCGGCCGTGGTGCAGATCGAGTCCGGCCTG
CAGATCGCGCAGACACGCGCCCAGGCCAATGGCGAGCGCGTGAGCGCCATCAAGGCGCTGCTGACGGTCAACAAGGACGC
GGTCGACGCGCTGATCGCCGGCATCGGCCAGTCGGTGGACGCCGCACGCGTGAGCATTCGCCAGATCGGGGAACTGGAAC
TGGTCTCGCGGCGTATCGACAAGATCGTCGACGCGATCACCACGGTCTCGATCCAGACCAATATGCTGGCGGTCAACGGC
TCGATCGAAGCCGCCCGTGCCGGCGAGTTCGGCAAGGGCTTCGTCGTGGTCGCGACCGACATCCGCAACCTTGCGCACGA
CTCGGCCGAGAACGCGGATCGCATCAAGGACCTGGTCAAGGCAGTCCAGGACCAAATCGGCGTGGTCGGTCGCGACCTCA
GCGATATCGCCGCCATCACCTCGAACGAAACCGAAAAGGCCAAGGCCAGCACCGCCAATCTGATCTCGATCGAAACCGAC
ATCGCCGCCGTGGAGACCGGTGCCGCCGAGGTCTTGGGCGCCGCCAATGACATTGCCAGCGCCATTGCCCAGGTTCGCAC
CGGCATGAATCAGATTTCGACCGCCGCGCAGGAGGCGGAAAAGGCCGCCGCCGAATCCGCGTCCGCGGCGCAGCAACAGT
CGCAAGGCACCGAAGAGCTGGCTGCCGCCATCGAGGAAATCTCCTCGCTGGCCGACGAACTGCAAAGCGCCTGA

Upstream 100 bases:

>100_bases
CTGAGCCCCGCCGCTCTTCTTTTCCCACTTCATGCCTGTCGTGGCTGCGGCCGCGTCGGTCTTCGTCGTACCGGTTCTTC
CCGACTAATAAGGACATGCA

Downstream 100 bases:

>100_bases
GCGCTGGCGAGATCCCATGAGCGATCAACTCTCCTCACAAGCATCGCCGCCGGCCGGCGACGCGGTGGACGCGGAACAGG
ACCACGTATCCAGCGGCCGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MALVRHSQKTADGASDGPRAVGSTRDAEAQRKRARTLAKQQQAAERIAAATTQLASGINEAASAAEELKRAADQIATGAE
EASGAAQESLTAFKLMEDAIARQRQSADTSQARVETTQILIARTTADVGGLVTNVGFVAQRQAASVQRVQELEQQAANIG
DIVKAVVRIADQTNLLALNAAIEAARAGKHGKGFAVVADEVRTLAETSEKSAKQIQDLVGQIQQEVKIVAEGINASARSI
ETEVAKGAAITEQLEQIRKDTIEIMTGATEIANGAQQSAAATQQALKGSESIAAAAEEQSAAAEESAKTVSEQARALNEC
EQTTQALSELAEDLKSSTDVAKSAEEVASAAEELSSAVQEINRSSAQILVAIDQIRKGAQVQARAIEDSVAAVVQIESGL
QIAQTRAQANGERVSAIKALLTVNKDAVDALIAGIGQSVDAARVSIRQIGELELVSRRIDKIVDAITTVSIQTNMLAVNG
SIEAARAGEFGKGFVVVATDIRNLAHDSAENADRIKDLVKAVQDQIGVVGRDLSDIAAITSNETEKAKASTANLISIETD
IAAVETGAAEVLGAANDIASAIAQVRTGMNQISTAAQEAEKAAAESASAAQQQSQGTEELAAAIEEISSLADELQSA

Sequences:

>Translated_637_residues
MALVRHSQKTADGASDGPRAVGSTRDAEAQRKRARTLAKQQQAAERIAAATTQLASGINEAASAAEELKRAADQIATGAE
EASGAAQESLTAFKLMEDAIARQRQSADTSQARVETTQILIARTTADVGGLVTNVGFVAQRQAASVQRVQELEQQAANIG
DIVKAVVRIADQTNLLALNAAIEAARAGKHGKGFAVVADEVRTLAETSEKSAKQIQDLVGQIQQEVKIVAEGINASARSI
ETEVAKGAAITEQLEQIRKDTIEIMTGATEIANGAQQSAAATQQALKGSESIAAAAEEQSAAAEESAKTVSEQARALNEC
EQTTQALSELAEDLKSSTDVAKSAEEVASAAEELSSAVQEINRSSAQILVAIDQIRKGAQVQARAIEDSVAAVVQIESGL
QIAQTRAQANGERVSAIKALLTVNKDAVDALIAGIGQSVDAARVSIRQIGELELVSRRIDKIVDAITTVSIQTNMLAVNG
SIEAARAGEFGKGFVVVATDIRNLAHDSAENADRIKDLVKAVQDQIGVVGRDLSDIAAITSNETEKAKASTANLISIETD
IAAVETGAAEVLGAANDIASAIAQVRTGMNQISTAAQEAEKAAAESASAAQQQSQGTEELAAAIEEISSLADELQSA
>Mature_636_residues
ALVRHSQKTADGASDGPRAVGSTRDAEAQRKRARTLAKQQQAAERIAAATTQLASGINEAASAAEELKRAADQIATGAEE
ASGAAQESLTAFKLMEDAIARQRQSADTSQARVETTQILIARTTADVGGLVTNVGFVAQRQAASVQRVQELEQQAANIGD
IVKAVVRIADQTNLLALNAAIEAARAGKHGKGFAVVADEVRTLAETSEKSAKQIQDLVGQIQQEVKIVAEGINASARSIE
TEVAKGAAITEQLEQIRKDTIEIMTGATEIANGAQQSAAATQQALKGSESIAAAAEEQSAAAEESAKTVSEQARALNECE
QTTQALSELAEDLKSSTDVAKSAEEVASAAEELSSAVQEINRSSAQILVAIDQIRKGAQVQARAIEDSVAAVVQIESGLQ
IAQTRAQANGERVSAIKALLTVNKDAVDALIAGIGQSVDAARVSIRQIGELELVSRRIDKIVDAITTVSIQTNMLAVNGS
IEAARAGEFGKGFVVVATDIRNLAHDSAENADRIKDLVKAVQDQIGVVGRDLSDIAAITSNETEKAKASTANLISIETDI
AAVETGAAEVLGAANDIASAIAQVRTGMNQISTAAQEAEKAAAESASAAQQQSQGTEELAAAIEEISSLADELQSA

Specific function: Mediates Taxis Toward Dipeptides VIa An Interaction With The Periplasmic Dipeptide-Binding Protein. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Transduce A Signal From The Outsid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=210, Percent_Identity=35.2380952380952, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789453, Length=105, Percent_Identity=45.7142857142857, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367378, Length=183, Percent_Identity=35.5191256830601, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787690, Length=157, Percent_Identity=37.5796178343949, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788195, Length=193, Percent_Identity=34.1968911917098, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66059; Mature: 65928

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVRHSQKTADGASDGPRAVGSTRDAEAQRKRARTLAKQQQAAERIAAATTQLASGINE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASAAEELKRAADQIATGAEEASGAAQESLTAFKLMEDAIARQRQSADTSQARVETTQIL
HHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHE
IARTTADVGGLVTNVGFVAQRQAASVQRVQELEQQAANIGDIVKAVVRIADQTNLLALNA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHH
AIEAARAGKHGKGFAVVADEVRTLAETSEKSAKQIQDLVGQIQQEVKIVAEGINASARSI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ETEVAKGAAITEQLEQIRKDTIEIMTGATEIANGAQQSAAATQQALKGSESIAAAAEEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAAEESAKTVSEQARALNECEQTTQALSELAEDLKSSTDVAKSAEEVASAAEELSSAVQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INRSSAQILVAIDQIRKGAQVQARAIEDSVAAVVQIESGLQIAQTRAQANGERVSAIKAL
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
LTVNKDAVDALIAGIGQSVDAARVSIRQIGELELVSRRIDKIVDAITTVSIQTNMLAVNG
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
SIEAARAGEFGKGFVVVATDIRNLAHDSAENADRIKDLVKAVQDQIGVVGRDLSDIAAIT
CCCHHHCCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SNETEKAKASTANLISIETDIAAVETGAAEVLGAANDIASAIAQVRTGMNQISTAAQEAE
CCCHHHHHHHHHHEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAAESASAAQQQSQGTEELAAAIEEISSLADELQSA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALVRHSQKTADGASDGPRAVGSTRDAEAQRKRARTLAKQQQAAERIAAATTQLASGINE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASAAEELKRAADQIATGAEEASGAAQESLTAFKLMEDAIARQRQSADTSQARVETTQIL
HHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHE
IARTTADVGGLVTNVGFVAQRQAASVQRVQELEQQAANIGDIVKAVVRIADQTNLLALNA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEHHHH
AIEAARAGKHGKGFAVVADEVRTLAETSEKSAKQIQDLVGQIQQEVKIVAEGINASARSI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ETEVAKGAAITEQLEQIRKDTIEIMTGATEIANGAQQSAAATQQALKGSESIAAAAEEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAAEESAKTVSEQARALNECEQTTQALSELAEDLKSSTDVAKSAEEVASAAEELSSAVQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INRSSAQILVAIDQIRKGAQVQARAIEDSVAAVVQIESGLQIAQTRAQANGERVSAIKAL
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
LTVNKDAVDALIAGIGQSVDAARVSIRQIGELELVSRRIDKIVDAITTVSIQTNMLAVNG
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
SIEAARAGEFGKGFVVVATDIRNLAHDSAENADRIKDLVKAVQDQIGVVGRDLSDIAAIT
CCCHHHCCCCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SNETEKAKASTANLISIETDIAAVETGAAEVLGAANDIASAIAQVRTGMNQISTAAQEAE
CCCHHHHHHHHHHEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAAAESASAAQQQSQGTEELAAAIEEISSLADELQSA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]