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The map label for this gene is frzE [H]

Identifier: 238025316

GI number: 238025316

Start: 2474353

End: 2474724

Strand: Reverse

Name: frzE [H]

Synonym: bglu_2g19900

Alternate gene names: 238025316

Gene position: 2474724-2474353 (Counterclockwise)

Preceding gene: 238025317

Following gene: 238025315

Centisome position: 87.53

GC content: 61.83

Gene sequence:

>372_bases
ATGAAGCGCGTCCTGATCATCGACGACGCATCAACCGTGCGTTTCTATCACCGCAGCATCCTGGAAAGCGCGGGCCATGC
GGTGGAGGAGGCCATCAACGGCATCGAGGCGCTCGAAAAGGCCCTGTGCGCGCCGTATGACCTTTACCTGGTCGACGTCA
ACATGCCCAAGCTCGACGGCTACGGTTTCCTGCGTGAGCTGCGCAACCAGCCGATCGTGCAGGCACCGGCGCTGATGGTC
TCCACCGAGGCGGACCCGATCGACGAGCACAAGGCCTATGCCGCCGGCGCCAATTTCTATCTGGTCAAACCGGCCAAGGC
CGAAGAATTGCTGGCCTATGTCGGCCTGTTGCTCGGGGAGAATGCAGCGTGA

Upstream 100 bases:

>100_bases
TCTGCTTGGGCCACTCCGAATCGATGAGCCGGATTTCTCCGCTGTTTCGCGTGCGCAAGTTCCCCGAAGCCATTGTCTAC
CAGAAGCCATTGGAGGATCG

Downstream 100 bases:

>100_bases
CGCCTTTGCTTGCCCAGTTCATCGCCGAATCGCGCGACATTCTGCAGTCGATCGGCCGGCACCTGATCGACATGGAGCTG
GCGCCCGACGATGGCGCGCT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MKRVLIIDDASTVRFYHRSILESAGHAVEEAINGIEALEKALCAPYDLYLVDVNMPKLDGYGFLRELRNQPIVQAPALMV
STEADPIDEHKAYAAGANFYLVKPAKAEELLAYVGLLLGENAA

Sequences:

>Translated_123_residues
MKRVLIIDDASTVRFYHRSILESAGHAVEEAINGIEALEKALCAPYDLYLVDVNMPKLDGYGFLRELRNQPIVQAPALMV
STEADPIDEHKAYAAGANFYLVKPAKAEELLAYVGLLLGENAA
>Mature_123_residues
MKRVLIIDDASTVRFYHRSILESAGHAVEEAINGIEALEKALCAPYDLYLVDVNMPKLDGYGFLRELRNQPIVQAPALMV
STEADPIDEHKAYAAGANFYLVKPAKAEELLAYVGLLLGENAA

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=39.0909090909091, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=123, Percent_Identity=34.1463414634146, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=31.25, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 13491; Mature: 13491

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLIIDDASTVRFYHRSILESAGHAVEEAINGIEALEKALCAPYDLYLVDVNMPKLDG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YGFLRELRNQPIVQAPALMVSTEADPIDEHKAYAAGANFYLVKPAKAEELLAYVGLLLGE
HHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCC
NAA
CCC
>Mature Secondary Structure
MKRVLIIDDASTVRFYHRSILESAGHAVEEAINGIEALEKALCAPYDLYLVDVNMPKLDG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YGFLRELRNQPIVQAPALMVSTEADPIDEHKAYAAGANFYLVKPAKAEELLAYVGLLLGE
HHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCC
NAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]