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The map label for this gene is ldh [H]

Identifier: 238025252

GI number: 238025252

Start: 2396391

End: 2397446

Strand: Reverse

Name: ldh [H]

Synonym: bglu_2g19240

Alternate gene names: 238025252

Gene position: 2397446-2396391 (Counterclockwise)

Preceding gene: 238025253

Following gene: 238025240

Centisome position: 84.8

GC content: 70.74

Gene sequence:

>1056_bases
ATGCAGATATCCCTCGACGATGCGATTGCATTCGGCAAGCAGGTGCTGGGCGCGCTGAAGGTGCCCGACGACATCGCCGA
CGACGTCGCCCGCCATCTGGTCGAAGCGGACCGCGTCGGCTACACCAGCCACGGCGTGTCGATCCTGCCGACCTACTGCC
AGGTGCTCGCGGACGGCCTGATCGACCCGGCCGGCCGCCCGAGCGTGCTGGCCGATCACGGCAGCCTGCTGATGTTCGAG
GGCAACCGCGGGCTCGGCCAGCACGTCGGCAAGGTGGTGGTGGAGCGGGCGATGACGCGCGCGCTCGACCGCGGCGTCTG
CATCCTGACCCTGCGCAACAGCCACCACCTGGGCCGGATGGGCCAGTACGGCGAGATGTGCGCGCACGCCGGCCTGGTGT
TCATGGCGTTCGCCAACGTCACCAACCTCGCGCCGATGGTGGCGCCGGTCGGCGGCGCCGAGCCGCGCCTGACCTCCAAC
CCGCTGTGCTTCGCCGGGCCGCTGCCGAACGACCGGCCGCCGCTGGTGGTGGACATGGCCACCAGCGCGATCGCCGTGAA
CAAGGCGCGCGTGCTGGCGGCCAACGGCATGAAGGCGCCGCCGGGCTCGCTGATCGACAGCCGGGGCTGTCCGACCGACG
ACCCGAACGTGCTGCAGGCCGATCCGCCCGGCTCGCTGCTGCCGTTCGGTGCCCATAAGGGCTATGCGCTCGGCGTGGTG
GCCGAACTGCTGGCGGGCGTGCTGTCGGGCGGCGGCACGATCCAGCCCGGCAACCCTCGGCAGGGCGCCGTGACCAACAA
CATGTTTGCGATCGTGCTGAACCCGCAGATGGATTGCTCGTCCCCCTGGCGCTCGCACGAGGTGGAGGCGTTCATCGAAT
ACCTGCTGTCCTGCCCGCGGCAGCCCGGCGCCGACCCCGTGCAGTACCCGGGCGAGTACGAGGCGCGCAACCGCCAGAAG
TACCACGATCACATCGAGCTGAGCACGCCGATCTGGGCGTCGCTGACGCGGATGGCCGACGAACTCGGCGTGGTGCCGCC
GGCCGCACGGGCCTAG

Upstream 100 bases:

>100_bases
CAGCGTGACCGGCTCGGCGCGGCTGCCGGTGTTCGGCGCCGCCTATTGGCGCCGGCTCGGCTGGCTGTAAGGCATGCAAC
CGGAAAAGGAGGTTCACGAC

Downstream 100 bases:

>100_bases
CCTCGTCGGTCTCGTCGGTCTCGTCTGTCGGGGCGGGGCGGAGGGCGTTCAGGCCCGCACGAGGCCGCTGGTCGCGTGCC
GCGCGCCGGCCTGCCCGAAC

Product: L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQISLDDAIAFGKQVLGALKVPDDIADDVARHLVEADRVGYTSHGVSILPTYCQVLADGLIDPAGRPSVLADHGSLLMFE
GNRGLGQHVGKVVVERAMTRALDRGVCILTLRNSHHLGRMGQYGEMCAHAGLVFMAFANVTNLAPMVAPVGGAEPRLTSN
PLCFAGPLPNDRPPLVVDMATSAIAVNKARVLAANGMKAPPGSLIDSRGCPTDDPNVLQADPPGSLLPFGAHKGYALGVV
AELLAGVLSGGGTIQPGNPRQGAVTNNMFAIVLNPQMDCSSPWRSHEVEAFIEYLLSCPRQPGADPVQYPGEYEARNRQK
YHDHIELSTPIWASLTRMADELGVVPPAARA

Sequences:

>Translated_351_residues
MQISLDDAIAFGKQVLGALKVPDDIADDVARHLVEADRVGYTSHGVSILPTYCQVLADGLIDPAGRPSVLADHGSLLMFE
GNRGLGQHVGKVVVERAMTRALDRGVCILTLRNSHHLGRMGQYGEMCAHAGLVFMAFANVTNLAPMVAPVGGAEPRLTSN
PLCFAGPLPNDRPPLVVDMATSAIAVNKARVLAANGMKAPPGSLIDSRGCPTDDPNVLQADPPGSLLPFGAHKGYALGVV
AELLAGVLSGGGTIQPGNPRQGAVTNNMFAIVLNPQMDCSSPWRSHEVEAFIEYLLSCPRQPGADPVQYPGEYEARNRQK
YHDHIELSTPIWASLTRMADELGVVPPAARA
>Mature_351_residues
MQISLDDAIAFGKQVLGALKVPDDIADDVARHLVEADRVGYTSHGVSILPTYCQVLADGLIDPAGRPSVLADHGSLLMFE
GNRGLGQHVGKVVVERAMTRALDRGVCILTLRNSHHLGRMGQYGEMCAHAGLVFMAFANVTNLAPMVAPVGGAEPRLTSN
PLCFAGPLPNDRPPLVVDMATSAIAVNKARVLAANGMKAPPGSLIDSRGCPTDDPNVLQADPPGSLLPFGAHKGYALGVV
AELLAGVLSGGGTIQPGNPRQGAVTNNMFAIVLNPQMDCSSPWRSHEVEAFIEYLLSCPRQPGADPVQYPGEYEARNRQK
YHDHIELSTPIWASLTRMADELGVVPPAARA

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=342, Percent_Identity=34.7953216374269, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1790000, Length=339, Percent_Identity=25.9587020648968, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786727, Length=321, Percent_Identity=28.6604361370716, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17507179, Length=357, Percent_Identity=30.812324929972, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17536633, Length=323, Percent_Identity=23.2198142414861, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667904, Length=254, Percent_Identity=32.2834645669291, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667908, Length=254, Percent_Identity=32.2834645669291, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45553211, Length=254, Percent_Identity=32.2834645669291, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24667912, Length=254, Percent_Identity=32.2834645669291, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24658010, Length=353, Percent_Identity=26.9121813031161, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24648360, Length=352, Percent_Identity=23.5795454545455, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: =1.1.1.27 [H]

Molecular weight: Translated: 37153; Mature: 37153

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISLDDAIAFGKQVLGALKVPDDIADDVARHLVEADRVGYTSHGVSILPTYCQVLADGL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
IDPAGRPSVLADHGSLLMFEGNRGLGQHVGKVVVERAMTRALDRGVCILTLRNSHHLGRM
CCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
GQYGEMCAHAGLVFMAFANVTNLAPMVAPVGGAEPRLTSNPLCFAGPLPNDRPPLVVDMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEC
TSAIAVNKARVLAANGMKAPPGSLIDSRGCPTDDPNVLQADPPGSLLPFGAHKGYALGVV
CHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
AELLAGVLSGGGTIQPGNPRQGAVTNNMFAIVLNPQMDCSSPWRSHEVEAFIEYLLSCPR
HHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
QPGADPVQYPGEYEARNRQKYHDHIELSTPIWASLTRMADELGVVPPAARA
CCCCCCCCCCCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQISLDDAIAFGKQVLGALKVPDDIADDVARHLVEADRVGYTSHGVSILPTYCQVLADGL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
IDPAGRPSVLADHGSLLMFEGNRGLGQHVGKVVVERAMTRALDRGVCILTLRNSHHLGRM
CCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
GQYGEMCAHAGLVFMAFANVTNLAPMVAPVGGAEPRLTSNPLCFAGPLPNDRPPLVVDMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEC
TSAIAVNKARVLAANGMKAPPGSLIDSRGCPTDDPNVLQADPPGSLLPFGAHKGYALGVV
CHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
AELLAGVLSGGGTIQPGNPRQGAVTNNMFAIVLNPQMDCSSPWRSHEVEAFIEYLLSCPR
HHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
QPGADPVQYPGEYEARNRQKYHDHIELSTPIWASLTRMADELGVVPPAARA
CCCCCCCCCCCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]