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The map label for this gene is ndh [H]

Identifier: 238024945

GI number: 238024945

Start: 2020273

End: 2021643

Strand: Reverse

Name: ndh [H]

Synonym: bglu_2g16000

Alternate gene names: 238024945

Gene position: 2021643-2020273 (Counterclockwise)

Preceding gene: 238024946

Following gene: 238024944

Centisome position: 71.5

GC content: 70.09

Gene sequence:

>1371_bases
ATGCATCGTTTCATCATCATAGGCGGCGGTGCCGGCGGGCTCGAACTCGCGACCCGGCTCGGCGACCGCTATGGCGCACG
CGGCAGGCGCGAGGCCCGCGCCCACGTCACGCTCGTCGACCGTCATCCGACGCACATCTGGAAACCGCTGCTGCACGAGG
TGGCCGCGGGCAGCATGGACCCTTTTACACAGGAGCTTGAATATGCGGCCCAGGCGCGCTGGCATGGCTTTGAGTTCCAG
CAGGGCGAACTGATCTCGATCGACCGCGGGGCCCGCCGCGTCTTGGTGGCCGCCGTCCACGACGGCGACGGCCTCGAACT
GATGCCCGAGCGCGAGCTCGAATACGACACGCTGGTGATCGCGATCGGCAGTACCACCCACTTCTTCGGTGTCGAGGGCG
CGCAGCAGCACGCCATCGCGCTCGACACGGTGAGCGAGGCGGAGCGTTTTCGCAAGCGTCTGATCGCGGCCTGCATCCGC
GCCGAGCATCGCGTGCCGGAGCCCGCGCAGCCCGGCGTCGAACCCGACCGGCCGCAGGCGGCTCACCCGGCGGAGCCGGC
CGAACCGCGCGTCCAGGTCGTGATCGTCGGGGCCGGCGCGACCGGCGTGGAGCTGTCCGCCGAGTTGCGCAATACCGCTC
AGGTCCTGGCCGCGTATGGTCTGCACAAGCTCGACCCGCAGCGCGACGTCGGCATCGTGCTGATCGAGTCGGGGCCGCGC
ATCCTGCCCGCGCTGCCCGAGCGCGTGGCGAACGCGACGGCCGAACTACTCGGGAAACTCGGCGTGCGGCTGATGACGGG
CGAGCGCGTGACCGAGGTCGCGCCGGGATGCGTGCGTACCGCGAGCGGCCAGTCGGTGCGCGCCGACCTGACGGTCTGGG
CAGCCGGCATCAAGGCGCCGGCCTTGCTATCGCAGCTCGATGGCCTCGAGGTGAACCGGCTCGGCCAGCTCGTGGTGCGC
CAGACGCTGCAGACCACGCTCGACGACGACGTGTTCGCGCTGGGCGATTGCGCCGCCTGCGCGTGGCCGGGTAACGATCG
CGGCGTGCCGCCGCGCGCGCAGGCCGCGCACCAGCAGGCGAGCTTCCTGCTGCGTGCGCTGGCCTGCCGGCTCGAACGGC
GGCCGCTGCCGTCATTCACCTATCGCGATTTCGGCTCGCTGGTGTCGCTCGGCCACTTCAGCGCAGTCGGCAGCCTGATG
GGCGGCCTGATCGGCGGCAACATGCTGATCGAGGGCTTGTTCGCGCGCTTCATGTACATGTCGCTGTACCGGCTCCATAT
CGCTGCGCTGCATGGCTATCCCCGCATGATGCTCGACACCGTGGCGCACTGGCTGCGCCGCTCCACGCTGCCGCGCGTGA
AGCTGCACTGA

Upstream 100 bases:

>100_bases
GCGCCGTGCCATCGCCATCCTGCGAAGCGGGCGCGCCGGCCGCCGGAGACGCCGCTTCGCCTCCGGTCGCATGCGTTACT
GAACCGCGAAAGGGGGATCG

Downstream 100 bases:

>100_bases
CGCGCCCCGAAGCACCGCGCGCCGGGCCGGCGGTGCGCCGACGGCCGGCGCCACCCGGCGCGGCGTGCTCGAAACAGTTG
ACGGCGCCGGCCATGTTTCG

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MHRFIIIGGGAGGLELATRLGDRYGARGRREARAHVTLVDRHPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELISIDRGARRVLVAAVHDGDGLELMPERELEYDTLVIAIGSTTHFFGVEGAQQHAIALDTVSEAERFRKRLIAACIR
AEHRVPEPAQPGVEPDRPQAAHPAEPAEPRVQVVIVGAGATGVELSAELRNTAQVLAAYGLHKLDPQRDVGIVLIESGPR
ILPALPERVANATAELLGKLGVRLMTGERVTEVAPGCVRTASGQSVRADLTVWAAGIKAPALLSQLDGLEVNRLGQLVVR
QTLQTTLDDDVFALGDCAACAWPGNDRGVPPRAQAAHQQASFLLRALACRLERRPLPSFTYRDFGSLVSLGHFSAVGSLM
GGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMMLDTVAHWLRRSTLPRVKLH

Sequences:

>Translated_456_residues
MHRFIIIGGGAGGLELATRLGDRYGARGRREARAHVTLVDRHPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELISIDRGARRVLVAAVHDGDGLELMPERELEYDTLVIAIGSTTHFFGVEGAQQHAIALDTVSEAERFRKRLIAACIR
AEHRVPEPAQPGVEPDRPQAAHPAEPAEPRVQVVIVGAGATGVELSAELRNTAQVLAAYGLHKLDPQRDVGIVLIESGPR
ILPALPERVANATAELLGKLGVRLMTGERVTEVAPGCVRTASGQSVRADLTVWAAGIKAPALLSQLDGLEVNRLGQLVVR
QTLQTTLDDDVFALGDCAACAWPGNDRGVPPRAQAAHQQASFLLRALACRLERRPLPSFTYRDFGSLVSLGHFSAVGSLM
GGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMMLDTVAHWLRRSTLPRVKLH
>Mature_456_residues
MHRFIIIGGGAGGLELATRLGDRYGARGRREARAHVTLVDRHPTHIWKPLLHEVAAGSMDPFTQELEYAAQARWHGFEFQ
QGELISIDRGARRVLVAAVHDGDGLELMPERELEYDTLVIAIGSTTHFFGVEGAQQHAIALDTVSEAERFRKRLIAACIR
AEHRVPEPAQPGVEPDRPQAAHPAEPAEPRVQVVIVGAGATGVELSAELRNTAQVLAAYGLHKLDPQRDVGIVLIESGPR
ILPALPERVANATAELLGKLGVRLMTGERVTEVAPGCVRTASGQSVRADLTVWAAGIKAPALLSQLDGLEVNRLGQLVVR
QTLQTTLDDDVFALGDCAACAWPGNDRGVPPRAQAAHQQASFLLRALACRLERRPLPSFTYRDFGSLVSLGHFSAVGSLM
GGLIGGNMLIEGLFARFMYMSLYRLHIAALHGYPRMMLDTVAHWLRRSTLPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=456, Percent_Identity=46.2719298245614, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6320118, Length=458, Percent_Identity=23.1441048034935, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323794, Length=373, Percent_Identity=23.5924932975871, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=466, Percent_Identity=21.6738197424893, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49656; Mature: 49656

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRFIIIGGGAGGLELATRLGDRYGARGRREARAHVTLVDRHPTHIWKPLLHEVAAGSMD
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFQQGELISIDRGARRVLVAAVHDGDGLELMPERELEYDTLVI
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCEECCCCCCCCEEEEE
AIGSTTHFFGVEGAQQHAIALDTVSEAERFRKRLIAACIRAEHRVPEPAQPGVEPDRPQA
EECCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
AHPAEPAEPRVQVVIVGAGATGVELSAELRNTAQVLAAYGLHKLDPQRDVGIVLIESGPR
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHCCCCCCCCEEEEECCCCC
ILPALPERVANATAELLGKLGVRLMTGERVTEVAPGCVRTASGQSVRADLTVWAAGIKAP
CCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCCCEECCCCCCEEEEHEEEECCCCHH
ALLSQLDGLEVNRLGQLVVRQTLQTTLDDDVFALGDCAACAWPGNDRGVPPRAQAAHQQA
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHH
SFLLRALACRLERRPLPSFTYRDFGSLVSLGHFSAVGSLMGGLIGGNMLIEGLFARFMYM
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYRLHIAALHGYPRMMLDTVAHWLRRSTLPRVKLH
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MHRFIIIGGGAGGLELATRLGDRYGARGRREARAHVTLVDRHPTHIWKPLLHEVAAGSMD
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC
PFTQELEYAAQARWHGFEFQQGELISIDRGARRVLVAAVHDGDGLELMPERELEYDTLVI
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCEECCCCCCCCEEEEE
AIGSTTHFFGVEGAQQHAIALDTVSEAERFRKRLIAACIRAEHRVPEPAQPGVEPDRPQA
EECCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
AHPAEPAEPRVQVVIVGAGATGVELSAELRNTAQVLAAYGLHKLDPQRDVGIVLIESGPR
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHCCCCCCCCEEEEECCCCC
ILPALPERVANATAELLGKLGVRLMTGERVTEVAPGCVRTASGQSVRADLTVWAAGIKAP
CCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCCCEECCCCCCEEEEHEEEECCCCHH
ALLSQLDGLEVNRLGQLVVRQTLQTTLDDDVFALGDCAACAWPGNDRGVPPRAQAAHQQA
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCHHHHHHHHH
SFLLRALACRLERRPLPSFTYRDFGSLVSLGHFSAVGSLMGGLIGGNMLIEGLFARFMYM
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYRLHIAALHGYPRMMLDTVAHWLRRSTLPRVKLH
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]