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The map label for this gene is pip [H]

Identifier: 238024714

GI number: 238024714

Start: 1733321

End: 1734256

Strand: Direct

Name: pip [H]

Synonym: bglu_2g13510

Alternate gene names: 238024714

Gene position: 1733321-1734256 (Clockwise)

Preceding gene: 238024712

Following gene: 238024715

Centisome position: 61.31

GC content: 68.91

Gene sequence:

>936_bases
ATGTATCCACCTCTCGAACCCTACGCCCACGGCCATCTCGATACCGGCGACGGCCACCGCCTCTACTGGGAGCGCTGCGG
CACGCCCGGCGCGAAGCCGGCGGTGTTCCTGCACGGCGGCCCCGGGGCGGGTTGCGCGCCGCGCCATCGGCAGTTGTTCG
ACCCGGCGCGCTACGACGTCCTGCTGTTCGACCAGCGCGGCTGCGGTAGATCAACGCCGCACGCGAGCCTGCGGAACAAT
ACCACCTGGCATCTGGTCGATGATATCGAGCGGCTGCGCAACATGGTGGGAGCCGAGCGCTGGCTCGTGTTCGGCGGATC
GTGGGGCAGCGCCCTCGCGCTCGCCTATGCCGAAACGCATCCGGCGCGCGTCAGCGAGCTGGTCGTGCGCGGTATCTTCA
CGCTACGGCATGCCGAGCTGCTCTGGTATTACCAGGAAGGCGCCTCGTGGCTGTTTCCGGACCTGTGGGAGTCGTTTCTC
GCGCCGATCCCGCAAGCCGAGCGCGGCGACCTGATCAGCGCCTACCACCGCCGCCTGACGGGCGACGACGAGGCGGCGAA
ACTCGAGGCCGCGATCGCCTGGAGCGTTTGGGAAAGCCGCACCATCACCCTGCTGCCGAACCCGCAGCTGGCCGCCCAGT
ACGGCGAGGCCCACTACGCGCTGGCGTTCGCGCGGATCGAAAACCACTATTTCGTCAATCGTGGTTTCATCGAGGAAGGA
CAGCTGCTGCGCGATGCCCACCGGCTCGCGTCGATCCCCGGCGTGATCGTGCAGGGCCGCTATGACGTCGCGACGCCGGC
CAGGAGCGCATGGGATCTCGCCAAGGCCTGGCCGGGCGCGAGCCTCGAAATCGTCGCCGATGCCGGCCACGCGTTCGACG
AGCCCGGCATCCTGCGCGCGTTGCTGGCGGCCACGGACCGCTTCGCGGCGACGTGA

Upstream 100 bases:

>100_bases
CGCGCAGCGATGATTCCGCCGCGGCACCCGGGCGGCCTGCCGGCACGGCAGCCGCGTCGCCCTCGTCCTCGTAACCGGCC
CTCCCTGCGGAGTTCGCAGC

Downstream 100 bases:

>100_bases
GCGAGCCCGGCGCGGCGCGCCCGCCAAGCGCCGCGGCAGCTGCGCCGGCCCCGGCCTGGCGCCGGGCCGCCGGCGATTTT
TCAACAACTGTCAGGCAACA

Product: Proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MYPPLEPYAHGHLDTGDGHRLYWERCGTPGAKPAVFLHGGPGAGCAPRHRQLFDPARYDVLLFDQRGCGRSTPHASLRNN
TTWHLVDDIERLRNMVGAERWLVFGGSWGSALALAYAETHPARVSELVVRGIFTLRHAELLWYYQEGASWLFPDLWESFL
APIPQAERGDLISAYHRRLTGDDEAAKLEAAIAWSVWESRTITLLPNPQLAAQYGEAHYALAFARIENHYFVNRGFIEEG
QLLRDAHRLASIPGVIVQGRYDVATPARSAWDLAKAWPGASLEIVADAGHAFDEPGILRALLAATDRFAAT

Sequences:

>Translated_311_residues
MYPPLEPYAHGHLDTGDGHRLYWERCGTPGAKPAVFLHGGPGAGCAPRHRQLFDPARYDVLLFDQRGCGRSTPHASLRNN
TTWHLVDDIERLRNMVGAERWLVFGGSWGSALALAYAETHPARVSELVVRGIFTLRHAELLWYYQEGASWLFPDLWESFL
APIPQAERGDLISAYHRRLTGDDEAAKLEAAIAWSVWESRTITLLPNPQLAAQYGEAHYALAFARIENHYFVNRGFIEEG
QLLRDAHRLASIPGVIVQGRYDVATPARSAWDLAKAWPGASLEIVADAGHAFDEPGILRALLAATDRFAAT
>Mature_311_residues
MYPPLEPYAHGHLDTGDGHRLYWERCGTPGAKPAVFLHGGPGAGCAPRHRQLFDPARYDVLLFDQRGCGRSTPHASLRNN
TTWHLVDDIERLRNMVGAERWLVFGGSWGSALALAYAETHPARVSELVVRGIFTLRHAELLWYYQEGASWLFPDLWESFL
APIPQAERGDLISAYHRRLTGDDEAAKLEAAIAWSVWESRTITLLPNPQLAAQYGEAHYALAFARIENHYFVNRGFIEEG
QLLRDAHRLASIPGVIVQGRYDVATPARSAWDLAKAWPGASLEIVADAGHAFDEPGILRALLAATDRFAAT

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 34584; Mature: 34584

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPPLEPYAHGHLDTGDGHRLYWERCGTPGAKPAVFLHGGPGAGCAPRHRQLFDPARYDV
CCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEE
LLFDQRGCGRSTPHASLRNNTTWHLVDDIERLRNMVGAERWLVFGGSWGSALALAYAETH
EEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCHHEEEEECCCC
PARVSELVVRGIFTLRHAELLWYYQEGASWLFPDLWESFLAPIPQAERGDLISAYHRRLT
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GDDEAAKLEAAIAWSVWESRTITLLPNPQLAAQYGEAHYALAFARIENHYFVNRGFIEEG
CCCHHHHHHHHEEEEECCCCEEEEECCCHHHHHHCCHHHEEEEEECCCEEEEECCCCCCC
QLLRDAHRLASIPGVIVQGRYDVATPARSAWDLAKAWPGASLEIVADAGHAFDEPGILRA
HHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHH
LLAATDRFAAT
HHHHHHHHCCC
>Mature Secondary Structure
MYPPLEPYAHGHLDTGDGHRLYWERCGTPGAKPAVFLHGGPGAGCAPRHRQLFDPARYDV
CCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCEE
LLFDQRGCGRSTPHASLRNNTTWHLVDDIERLRNMVGAERWLVFGGSWGSALALAYAETH
EEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCHHEEEEECCCC
PARVSELVVRGIFTLRHAELLWYYQEGASWLFPDLWESFLAPIPQAERGDLISAYHRRLT
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GDDEAAKLEAAIAWSVWESRTITLLPNPQLAAQYGEAHYALAFARIENHYFVNRGFIEEG
CCCHHHHHHHHEEEEECCCCEEEEECCCHHHHHHCCHHHEEEEEECCCEEEEECCCCCCC
QLLRDAHRLASIPGVIVQGRYDVATPARSAWDLAKAWPGASLEIVADAGHAFDEPGILRA
HHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHH
LLAATDRFAAT
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]