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The map label for this gene is murA [H]

Identifier: 238024623

GI number: 238024623

Start: 1577396

End: 1578694

Strand: Direct

Name: murA [H]

Synonym: bglu_2g12380

Alternate gene names: 238024623

Gene position: 1577396-1578694 (Clockwise)

Preceding gene: 238024622

Following gene: 238024625

Centisome position: 55.79

GC content: 67.9

Gene sequence:

>1299_bases
ATGTCGAACCTGATCGTCTACGGCGGCAACCCGCTACGCGGGGAAATCACGCCGTCCGCCAACAAGAACGCCGTCCTCCC
GATTCTCTGCGCCACCCTGCTGTCCGACCAGCCGCTCAGGCTGGTCGGCGTGCCGGACATCACCGACGTGCGCAAGATCC
TCGACATCTTCCGCACGCTCGGCAGCGAGGTCTCGATCGATTTCGCCACCGGCGTGCTCGATCTCCATCACCACGCGACG
CAGTTCGATTCGGCCGTGCACCGGCTGCCCGAGGAAATGCGCTCGTCGATCATGCTGGTGCCGCCGCTCCTGGCCCGCTT
CGGCGTGGCGCGGCTCGAGAACGACGTGAAGGGCTGCACGCTCGGCGTGCGCGAGATCGATCCGCACGTGGAAGTGTTCG
AGCGCTTCGGCGCGAGCATCGAGCGCACCAGCGATTCGCTGATCGTGCGTGCCACCAAGCTCACCCCGAACGACCACTGG
CTCGACTACGCGTCGGTCACCACCACCGAGAACTTCGTGCTCTGCGCGGCCGCCGCGGGCGGCGTGTCGACGCTGGTGAA
TGCGGCCTCGGAGCCGCACGTGCAGGAGTTCTGCCGCTTCCTCGCGATGCTCGGCGTGCCGATCGAAGGCATCGGCACCT
CGCACCTGCGCGTGCAGGGCGGCGTGAAGCTGGCGGGCGGCGAGCACCGCTTCGCCGAGGATTTCCACGAGATCGCCACG
TTCCTCGCGCTCGGCGCGATCACGGGCGGCGACATCGCGGTGCGCAACAGCGGCCCCGAGCAGTTTCCGCTGATCGACCG
CACGTTTGCCAAGCTCGGCGTGCAGGTCACGCACGCCAACGGCTGGTCGCACGCCACGCGCGACGGCGCGATGAAGGTGA
AGAAGCCGTTCACGCAGAACATCCTGACCAAGATCGAGGCCGCGCCGTGGCCCTACCTGCCCGTCGATCTGCTGCCGATC
TTCATCGCGCTGGGCGTCAAGGCCGAGGGCAGCGTGATGTTCTGGAACAAGGTGTACGACGGTGCGATGGGCTGGACGGG
CGAGCTGTCGAAGTTCGGCGCGCACGTGTTCCAGTCCGATCCGCACCGGCTGATCACGTTCGGCGGGCTGCCGCTCTCGC
CGGCGCGCGTCGAGAGCCCCTACATCATCCGCGTGGCGATCGCGCTGCTGATGGTGGCCGCCAGCATCGAGGGCCGCTCC
GAGATTCTCAACGCGCAGCCGATCCGCCGCGCCCATCCGCACTTCGTCGAGAACCTGCGCTCGGTCGGCGCGAACGTCGA
GTGGACGGCCGGCGACTGA

Upstream 100 bases:

>100_bases
GCATGGCAGGCGCCGCTGACGGACGGCCCGACTCGCGCCTCTGCCGCAAACGATGGCATGATACGGCCTTGCGCCACCTT
CATCGCTATCGCGCCGAACC

Downstream 100 bases:

>100_bases
TGCGCCGGCGCTGAACCCGGCACCGCGCGCCACGGCGCGCGCCGCTGCCGGCCCGGGTTTGCTGCCCGGGTTCGCTGCCC
GGGTTCGCTGCCCGGCTGCC

Product: putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSNLIVYGGNPLRGEITPSANKNAVLPILCATLLSDQPLRLVGVPDITDVRKILDIFRTLGSEVSIDFATGVLDLHHHAT
QFDSAVHRLPEEMRSSIMLVPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGASIERTSDSLIVRATKLTPNDHW
LDYASVTTTENFVLCAAAAGGVSTLVNAASEPHVQEFCRFLAMLGVPIEGIGTSHLRVQGGVKLAGGEHRFAEDFHEIAT
FLALGAITGGDIAVRNSGPEQFPLIDRTFAKLGVQVTHANGWSHATRDGAMKVKKPFTQNILTKIEAAPWPYLPVDLLPI
FIALGVKAEGSVMFWNKVYDGAMGWTGELSKFGAHVFQSDPHRLITFGGLPLSPARVESPYIIRVAIALLMVAASIEGRS
EILNAQPIRRAHPHFVENLRSVGANVEWTAGD

Sequences:

>Translated_432_residues
MSNLIVYGGNPLRGEITPSANKNAVLPILCATLLSDQPLRLVGVPDITDVRKILDIFRTLGSEVSIDFATGVLDLHHHAT
QFDSAVHRLPEEMRSSIMLVPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGASIERTSDSLIVRATKLTPNDHW
LDYASVTTTENFVLCAAAAGGVSTLVNAASEPHVQEFCRFLAMLGVPIEGIGTSHLRVQGGVKLAGGEHRFAEDFHEIAT
FLALGAITGGDIAVRNSGPEQFPLIDRTFAKLGVQVTHANGWSHATRDGAMKVKKPFTQNILTKIEAAPWPYLPVDLLPI
FIALGVKAEGSVMFWNKVYDGAMGWTGELSKFGAHVFQSDPHRLITFGGLPLSPARVESPYIIRVAIALLMVAASIEGRS
EILNAQPIRRAHPHFVENLRSVGANVEWTAGD
>Mature_431_residues
SNLIVYGGNPLRGEITPSANKNAVLPILCATLLSDQPLRLVGVPDITDVRKILDIFRTLGSEVSIDFATGVLDLHHHATQ
FDSAVHRLPEEMRSSIMLVPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGASIERTSDSLIVRATKLTPNDHWL
DYASVTTTENFVLCAAAAGGVSTLVNAASEPHVQEFCRFLAMLGVPIEGIGTSHLRVQGGVKLAGGEHRFAEDFHEIATF
LALGAITGGDIAVRNSGPEQFPLIDRTFAKLGVQVTHANGWSHATRDGAMKVKKPFTQNILTKIEAAPWPYLPVDLLPIF
IALGVKAEGSVMFWNKVYDGAMGWTGELSKFGAHVFQSDPHRLITFGGLPLSPARVESPYIIRVAIALLMVAASIEGRSE
ILNAQPIRRAHPHFVENLRSVGANVEWTAGD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=436, Percent_Identity=30.9633027522936, Blast_Score=181, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46878; Mature: 46747

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLIVYGGNPLRGEITPSANKNAVLPILCATLLSDQPLRLVGVPDITDVRKILDIFRTL
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHC
GSEVSIDFATGVLDLHHHATQFDSAVHRLPEEMRSSIMLVPPLLARFGVARLENDVKGCT
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCCCE
LGVREIDPHVEVFERFGASIERTSDSLIVRATKLTPNDHWLDYASVTTTENFVLCAAAAG
ECHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCC
GVSTLVNAASEPHVQEFCRFLAMLGVPIEGIGTSHLRVQGGVKLAGGEHRFAEDFHEIAT
CHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHH
FLALGAITGGDIAVRNSGPEQFPLIDRTFAKLGVQVTHANGWSHATRDGAMKVKKPFTQN
HHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCHHCCHHHHH
ILTKIEAAPWPYLPVDLLPIFIALGVKAEGSVMFWNKVYDGAMGWTGELSKFGAHVFQSD
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHCCC
PHRLITFGGLPLSPARVESPYIIRVAIALLMVAASIEGRSEILNAQPIRRAHPHFVENLR
CCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHCCHHHHHHHH
SVGANVEWTAGD
HHCCCEEEECCC
>Mature Secondary Structure 
SNLIVYGGNPLRGEITPSANKNAVLPILCATLLSDQPLRLVGVPDITDVRKILDIFRTL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHC
GSEVSIDFATGVLDLHHHATQFDSAVHRLPEEMRSSIMLVPPLLARFGVARLENDVKGCT
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCCCCE
LGVREIDPHVEVFERFGASIERTSDSLIVRATKLTPNDHWLDYASVTTTENFVLCAAAAG
ECHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCC
GVSTLVNAASEPHVQEFCRFLAMLGVPIEGIGTSHLRVQGGVKLAGGEHRFAEDFHEIAT
CHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHH
FLALGAITGGDIAVRNSGPEQFPLIDRTFAKLGVQVTHANGWSHATRDGAMKVKKPFTQN
HHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCHHCCHHHHH
ILTKIEAAPWPYLPVDLLPIFIALGVKAEGSVMFWNKVYDGAMGWTGELSKFGAHVFQSD
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHHCCC
PHRLITFGGLPLSPARVESPYIIRVAIALLMVAASIEGRSEILNAQPIRRAHPHFVENLR
CCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHCCHHHHHHHH
SVGANVEWTAGD
HHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]