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The map label for this gene is cph2 [H]

Identifier: 238024593

GI number: 238024593

Start: 1541372

End: 1542892

Strand: Reverse

Name: cph2 [H]

Synonym: bglu_2g12040

Alternate gene names: 238024593

Gene position: 1542892-1541372 (Counterclockwise)

Preceding gene: 238024594

Following gene: 238024592

Centisome position: 54.57

GC content: 72.52

Gene sequence:

>1521_bases
ATGAACGAGAGCACTGCCGGACGGCGCGGGTGGAGAGACCCGCCGCCCCGGATGCCGCTGGGTTACCTCGTGATCGCCGC
CGGCGTGGCGATCGCGCTGGTGATGATGACGATCTGCGCGGCGATCCTGCGGGACAGCCGCGTGGATGCGTTCGAGCGCG
CGCAGGACAGCGCGCGCAACACGCTGCTGATGATCGAGCGCGACGTGGCGCGCAGCCTGCACATCGACGATCTCGCGCTG
CAGGGCGTGATCGCGGGCCTGCGTGATCCATCGCTGGATGGCTTGCCGGCGGCGCTGCGGCGCCGCTTGCTGTTCGACCG
CGCGGCGGTGGCCAACGACATCGGCGGGATCTACGTGCTCGACGCCGAGGGCCGCCTGGTCCTGTCCTCCACCGACCTCG
ACACCGGCGACGAGCGCTTCGACGACCGCGATTTCTTCGCGGCGCAGCGCGACGATCCCGACACCGGCCTGTTCGTCAGC
AGCCCGTACACGTCGGTGCTGACCGGCGACGATCCGAGCATCGCGCTGTCGCGGCGGCTCAACGGCCCGGACGGGCGGTT
CGCCGGGGTGGTGGTGCTGGCGGTGCGGCTCCACTATTTCCGCCGGCTGTTCGCGGGGCTCACGCTCGGCCCGCACGGCT
CGATCGCGCTGATCCACGCCAACGGGCGGCTGATCATGCGCGCGCCGAGCGACGCGACGCTGATCGGGCGCGACCTGCGC
GGCACCGGCCCCTACACGCGCATGCTGGCGGGCGGCAGCGGCTCGTTCGTCGACGTCGCCTCGATCGACGGCGTGCGCCG
CAGCTACCTGTTCCAGCGCCTGCCGCGGCTGCCCGTGATCGTCCAGGTCGCGGTGGCCGAGCAGGACGTCTACGCCGAGT
GGCGCCGGCGCGCATGGCGCTTCGGGATTCTCACCGGCGCGTTCGGCATCGCGTTCGTGGTGCTGAGCGCCTGTCTCGCG
CATTCGCTGTGGCGCCAGTCGGAGGCCGAGGCCGCGCTTGCGCGGCTGGCCGGCACCGACAGCCTGACCGGCCTGCCGAA
CCGCCGCTCGCTGGACGCCTCGCTCGAACGCGAATGGCGCCGCGCGGTGCGGTCGCGGCGGCCGCTCGCGATCCTGTTCG
TCGATATCGACCACTTCAAGCGCTACAACGACGAATACGGCCACACGGTGGGCGACGAGGTGCTGGCCTGCGTGTCGGCC
AGCATCGCGCGGCAGGCGCTGCGCTCGCACGACGTGGTGGCGCGCTACGGCGGCGAGGAATTCGTGGTGGTGCTGCCCGA
TACCGACAGCGCCGGCGCGCGCGCCATCGGCGAGCGGATTCGCGACGCGGTGCGCGAGCTGGCGATCGCCCATGCCGGCT
CGGAGTCGGGCTACGTGACGGTCAGCGTGGGGGTCGCGACCTGGCGGCCCGAGGCCGGCTTCGCCGCGGACGTGGCGGTG
GTGGTGGACGCGGCCGACCAGGCGCTCTATCGCGCGAAGGAGGGCGGGCGCGACCGCGTGTTCGAGGCCGAACTGGCCTG
A

Upstream 100 bases:

>100_bases
GCGGCGCGTAAACGGCGTGGTTCCGCCGCGCCGCATCGGTGATAATGGCCGCTCGGCACACTTCACGGAACCGGCTCGCA
GCACGGTCCGCATGACAACG

Downstream 100 bases:

>100_bases
GCGCGGCGCACCGGTTCGCGGCCGGAAGGCCCGCCGCCGCGCAGCCCAACGTGCTTTAGCCCTCGTCGCCGGCCACCAAC
AGCGAGCCGTCCTGCCCAGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MNESTAGRRGWRDPPPRMPLGYLVIAAGVAIALVMMTICAAILRDSRVDAFERAQDSARNTLLMIERDVARSLHIDDLAL
QGVIAGLRDPSLDGLPAALRRRLLFDRAAVANDIGGIYVLDAEGRLVLSSTDLDTGDERFDDRDFFAAQRDDPDTGLFVS
SPYTSVLTGDDPSIALSRRLNGPDGRFAGVVVLAVRLHYFRRLFAGLTLGPHGSIALIHANGRLIMRAPSDATLIGRDLR
GTGPYTRMLAGGSGSFVDVASIDGVRRSYLFQRLPRLPVIVQVAVAEQDVYAEWRRRAWRFGILTGAFGIAFVVLSACLA
HSLWRQSEAEAALARLAGTDSLTGLPNRRSLDASLEREWRRAVRSRRPLAILFVDIDHFKRYNDEYGHTVGDEVLACVSA
SIARQALRSHDVVARYGGEEFVVVLPDTDSAGARAIGERIRDAVRELAIAHAGSESGYVTVSVGVATWRPEAGFAADVAV
VVDAADQALYRAKEGGRDRVFEAELA

Sequences:

>Translated_506_residues
MNESTAGRRGWRDPPPRMPLGYLVIAAGVAIALVMMTICAAILRDSRVDAFERAQDSARNTLLMIERDVARSLHIDDLAL
QGVIAGLRDPSLDGLPAALRRRLLFDRAAVANDIGGIYVLDAEGRLVLSSTDLDTGDERFDDRDFFAAQRDDPDTGLFVS
SPYTSVLTGDDPSIALSRRLNGPDGRFAGVVVLAVRLHYFRRLFAGLTLGPHGSIALIHANGRLIMRAPSDATLIGRDLR
GTGPYTRMLAGGSGSFVDVASIDGVRRSYLFQRLPRLPVIVQVAVAEQDVYAEWRRRAWRFGILTGAFGIAFVVLSACLA
HSLWRQSEAEAALARLAGTDSLTGLPNRRSLDASLEREWRRAVRSRRPLAILFVDIDHFKRYNDEYGHTVGDEVLACVSA
SIARQALRSHDVVARYGGEEFVVVLPDTDSAGARAIGERIRDAVRELAIAHAGSESGYVTVSVGVATWRPEAGFAADVAV
VVDAADQALYRAKEGGRDRVFEAELA
>Mature_506_residues
MNESTAGRRGWRDPPPRMPLGYLVIAAGVAIALVMMTICAAILRDSRVDAFERAQDSARNTLLMIERDVARSLHIDDLAL
QGVIAGLRDPSLDGLPAALRRRLLFDRAAVANDIGGIYVLDAEGRLVLSSTDLDTGDERFDDRDFFAAQRDDPDTGLFVS
SPYTSVLTGDDPSIALSRRLNGPDGRFAGVVVLAVRLHYFRRLFAGLTLGPHGSIALIHANGRLIMRAPSDATLIGRDLR
GTGPYTRMLAGGSGSFVDVASIDGVRRSYLFQRLPRLPVIVQVAVAEQDVYAEWRRRAWRFGILTGAFGIAFVVLSACLA
HSLWRQSEAEAALARLAGTDSLTGLPNRRSLDASLEREWRRAVRSRRPLAILFVDIDHFKRYNDEYGHTVGDEVLACVSA
SIARQALRSHDVVARYGGEEFVVVLPDTDSAGARAIGERIRDAVRELAIAHAGSESGYVTVSVGVATWRPEAGFAADVAV
VVDAADQALYRAKEGGRDRVFEAELA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=39.2638036809816, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87081881, Length=191, Percent_Identity=38.2198952879581, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=37.4269005847953, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=32.5714285714286, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787541, Length=190, Percent_Identity=35.2631578947368, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=37.5757575757576, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=35.0282485875706, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787802, Length=201, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=34.3023255813954, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081977, Length=215, Percent_Identity=32.5581395348837, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788381, Length=168, Percent_Identity=37.5, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081974, Length=205, Percent_Identity=27.3170731707317, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 55047; Mature: 55047

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESTAGRRGWRDPPPRMPLGYLVIAAGVAIALVMMTICAAILRDSRVDAFERAQDSARN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
TLLMIERDVARSLHIDDLALQGVIAGLRDPSLDGLPAALRRRLLFDRAAVANDIGGIYVL
EEEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
DAEGRLVLSSTDLDTGDERFDDRDFFAAQRDDPDTGLFVSSPYTSVLTGDDPSIALSRRL
CCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEECCCCCEEEEECC
NGPDGRFAGVVVLAVRLHYFRRLFAGLTLGPHGSIALIHANGRLIMRAPSDATLIGRDLR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCEEEECCCC
GTGPYTRMLAGGSGSFVDVASIDGVRRSYLFQRLPRLPVIVQVAVAEQDVYAEWRRRAWR
CCCCHHHEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
FGILTGAFGIAFVVLSACLAHSLWRQSEAEAALARLAGTDSLTGLPNRRSLDASLEREWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
RAVRSRRPLAILFVDIDHFKRYNDEYGHTVGDEVLACVSASIARQALRSHDVVARYGGEE
HHHHCCCCEEEEEEEHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCE
FVVVLPDTDSAGARAIGERIRDAVRELAIAHAGSESGYVTVSVGVATWRPEAGFAADVAV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEE
VVDAADQALYRAKEGGRDRVFEAELA
EEEHHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MNESTAGRRGWRDPPPRMPLGYLVIAAGVAIALVMMTICAAILRDSRVDAFERAQDSARN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
TLLMIERDVARSLHIDDLALQGVIAGLRDPSLDGLPAALRRRLLFDRAAVANDIGGIYVL
EEEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
DAEGRLVLSSTDLDTGDERFDDRDFFAAQRDDPDTGLFVSSPYTSVLTGDDPSIALSRRL
CCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEECCCCCEEEEECC
NGPDGRFAGVVVLAVRLHYFRRLFAGLTLGPHGSIALIHANGRLIMRAPSDATLIGRDLR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCEEEECCCC
GTGPYTRMLAGGSGSFVDVASIDGVRRSYLFQRLPRLPVIVQVAVAEQDVYAEWRRRAWR
CCCCHHHEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
FGILTGAFGIAFVVLSACLAHSLWRQSEAEAALARLAGTDSLTGLPNRRSLDASLEREWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
RAVRSRRPLAILFVDIDHFKRYNDEYGHTVGDEVLACVSASIARQALRSHDVVARYGGEE
HHHHCCCCEEEEEEEHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCE
FVVVLPDTDSAGARAIGERIRDAVRELAIAHAGSESGYVTVSVGVATWRPEAGFAADVAV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCEEE
VVDAADQALYRAKEGGRDRVFEAELA
EEEHHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]