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The map label for this gene is moaA [H]

Identifier: 23501841

GI number: 23501841

Start: 929288

End: 930322

Strand: Reverse

Name: moaA [H]

Synonym: BR0958

Alternate gene names: 23501841

Gene position: 930322-929288 (Counterclockwise)

Preceding gene: 23501843

Following gene: 23501840

Centisome position: 44.14

GC content: 58.45

Gene sequence:

>1035_bases
ATGCGCAATGTTCAAGCTCAGCCCCTTGTTTCTCCAACGGAACCGATGATCGATCCGTTCGGACGCGCCGTTACCTATCT
GCGCGTTTCAGTGACGGATCGCTGCGATTTCCGCTGCACCTACTGCATGGCGGAACATATGACCTTCCTGCCGAAGAAAG
ACCTTCTGACACTGGAGGAGCTGGACCGGCTTTGCAGTGTTTTCATCGAAAAGGGCGTACGCAAGCTTCGGCTCACCGGC
GGCGAGCCGCTGGTGCGCAAGAACATCATGCATCTGATCGGCAATCTTTCGCGCCATCTCAAATCGGGCGCGCTGGATGA
GCTGACACTGACCACCAACGGATCGCAGCTTGCCCGCTTCGCCGGGGAGCTTGCCGATTGCGGCGTTCGCCGTATCAATG
TTTCGCTCGACACACTCAACCCGGAAAAATTCCGCACGATCACCCGCTGGGGCGATCTGTCCCGTGTTTTGGAAGGCATT
GACGCCGCCCAAAAGGCCGGCATCCACGTCAAGATCAATGCGGTCGCGCTGAAAGACTTCAACGACGCCGAAATTCCGGA
ACTGATCCGCTGGGCGCACGGGCGCGGCATGGATGTGACGCTGATCGAAACCATGCCCATGGGAGAAATAGAATTTGACC
GTACCGATCAATATCTGCCGCTTTCGCAGGTCCGTGCCGATCTTGCCAGCCAGTTCACGCTTGCCGATATTCCCTATCGC
ACCGGCGGCCCTGCCCGCTATGTCACGATCAGCGAAACGGGCGGACGGCTTGGTTTCATCACACCGATGACGCATAATTT
CTGCGAAAGCTGCAACCGCGTCCGCCTCACATGCACCGGGATGCTTTATATGTGCCTCGGCCAGAACGACGATGCCGACC
TGCGCAAGGCGCTGCGCGAAAGCGAGAGCGACGAGCATCTGAGCCAAGCCATAGACGAGGCCATCTCCCGCAAGCCGAAA
GGGCATGATTTCATTATCGACCGTGAGCATAACCGCCCGTCCGTGGCCCGCCACATGAGCCTTACGGGCGGATGA

Upstream 100 bases:

>100_bases
TTCATGCGAGGGACAAACTGGACAATCCATGATCGAAAACCTATCTCTATCAGGAAGCGCGGATATTGTTCCGTGCCATG
CGAAAACAACGGCTTAATTT

Downstream 100 bases:

>100_bases
CGGGATTTAGTTTTTAAATCTCCTGCGGTCACTTAATTCGTCTCGACAGCCTGCGGCAAGGCAAAGCGCCGGGCGTTTAT
ACTGTTGCCGGTTCGGTCCT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEELDRLCSVFIEKGVRKLRLTG
GEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARFAGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGI
DAAQKAGIHVKINAVALKDFNDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYR
TGGPARYVTISETGGRLGFITPMTHNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRESESDEHLSQAIDEAISRKPK
GHDFIIDREHNRPSVARHMSLTGG

Sequences:

>Translated_344_residues
MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEELDRLCSVFIEKGVRKLRLTG
GEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARFAGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGI
DAAQKAGIHVKINAVALKDFNDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYR
TGGPARYVTISETGGRLGFITPMTHNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRESESDEHLSQAIDEAISRKPK
GHDFIIDREHNRPSVARHMSLTGG
>Mature_344_residues
MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEELDRLCSVFIEKGVRKLRLTG
GEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARFAGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGI
DAAQKAGIHVKINAVALKDFNDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYR
TGGPARYVTISETGGRLGFITPMTHNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRESESDEHLSQAIDEAISRKPK
GHDFIIDREHNRPSVARHMSLTGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=336, Percent_Identity=37.202380952381, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI22027536, Length=336, Percent_Identity=37.202380952381, Blast_Score=208, Evalue=6e-54,
Organism=Escherichia coli, GI1786999, Length=332, Percent_Identity=31.6265060240964, Blast_Score=185, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32566329, Length=336, Percent_Identity=37.797619047619, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI32566331, Length=335, Percent_Identity=36.4179104477612, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17561210, Length=336, Percent_Identity=36.9047619047619, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI28574488, Length=336, Percent_Identity=39.2857142857143, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI28574490, Length=321, Percent_Identity=39.5638629283489, Blast_Score=217, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 38604; Mature: 38604

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEE
CCCCCCCCCCCCCCHHHHHHHHEEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHH
LDRLCSVFIEKGVRKLRLTGGEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARF
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
AGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGIDAAQKAGIHVKINAVALKDF
HHHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
NDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYR
CCCCHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHCCEEECCCCC
TGGPARYVTISETGGRLGFITPMTHNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRE
CCCCEEEEEEECCCCEEEEECCCHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHC
SESDEHLSQAIDEAISRKPKGHDFIIDREHNRPSVARHMSLTGG
CCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MRNVQAQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEE
CCCCCCCCCCCCCCHHHHHHHHEEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHH
LDRLCSVFIEKGVRKLRLTGGEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARF
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
AGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGIDAAQKAGIHVKINAVALKDF
HHHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
NDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYR
CCCCHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHCCEEECCCCC
TGGPARYVTISETGGRLGFITPMTHNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRE
CCCCEEEEEEECCCCEEEEECCCHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHC
SESDEHLSQAIDEAISRKPKGHDFIIDREHNRPSVARHMSLTGG
CCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA