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The map label for this gene is qor [C]

Identifier: 23501739

GI number: 23501739

Start: 825803

End: 826831

Strand: Reverse

Name: qor [C]

Synonym: BR0852

Alternate gene names: 23501739

Gene position: 826831-825803 (Counterclockwise)

Preceding gene: 23501740

Following gene: 23501738

Centisome position: 39.23

GC content: 61.42

Gene sequence:

>1029_bases
ATGCGCGCCTTGCAGCTTCTCGATGATCGCCGCCTTGAAATCACCGATATTGCGCCCCCGCCGCTGCCCGGCATGGGGGA
AGTGACCGTTCGCATCAAGGCCGTGGCGCTCAACCATATCGATGTCTGGGGCTGGCGCGGCATGGCCTTTGCCAAGCGCA
AGATGCCGCTCGTCATCGGTGCAGAGGCTTCCGGTGTTGTCGATGCTGTCGGTCCCGGCGTTTCCAATCTCCTGCCCGGC
CAGCTCGTTTCCATCTATGGCGCGCGCACCTGCGGGCTTTGCCGCGCCTGCCGCGAAGGCCGTGACAATCTTTGCGAACA
TGTGGGCGGCGTGCATGGTTTCCATCTTGATGGCTTTGCCTGCGAAGCGGTGAACCTTCCCGCCCGCCTGCTGGTTGCCG
CCCCTCCCGGCGTGGATGCTATCGGCGCGGCTGTTGCTCCGGTCACATTCGGCACGGTGGAACATATGCTGTTCGACAAT
GCCAAGCTTGAACCCGGCGAAACCGTGCTCGTTCAGGCTGGCGGCTCAGGCATTGGCACGGCTGCGATCCAGCTTGCAAA
GAAGATGGGCTGCACAGTCATCACCACAGTCGGCTCCAACGACAAGATCGAGAAGGCCAAGGCTCTTGGCGCCGATCACG
TCATCAATTACCGCGAGGACCGTTTCGAGGGCGTGGTGCGCAAGCTCACCAAGAAGAAGGGCGTGGATGTGGTGTTCGAG
CATGTGGGCGCGGACACATGGGCAGGCTCCATGCTGTGCATGAAGCGCGGCGCGCGTCTCGTCACCTGCGGCTCGACCTC
GGGCGTTTCCACGAACATGAACCTGATGCAGCTTTTCCAGCAGCAGTTGAAGATTTTCGGCTCCTTCGGCTGCCGCATGG
AAAACATGGCCGACGCCATGCAGAAGATGGCACGCGGCATCGTGCATCCGGTCATCGACACCGTGGTTGGCTTTAGCGAT
ATCGACACGGCGCTGAAGCGCATGGAAGGCCGCGACGTCTTCGGCAAGATCATTCTCCAGATCGACTGA

Upstream 100 bases:

>100_bases
GACGCCAAATCCGAATTAATCCGTCCGTAATCGAATTCAAATTCCTGATGATCCCGGAAGGCGAAAGCTCTCCGGGATCA
TGCCATGAAAGGAACAGCCC

Downstream 100 bases:

>100_bases
GCCCGTCACGTCCATGATGTTCAAGCTGAAACTTCTGCTCTTCCGCTGGTCGCGCAAGCTGAAGCAATTCAATTACTGGC
TCTGGGCACAAGCCGTTTTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRALQLLDDRRLEITDIAPPPLPGMGEVTVRIKAVALNHIDVWGWRGMAFAKRKMPLVIGAEASGVVDAVGPGVSNLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVGGVHGFHLDGFACEAVNLPARLLVAAPPGVDAIGAAVAPVTFGTVEHMLFDN
AKLEPGETVLVQAGGSGIGTAAIQLAKKMGCTVITTVGSNDKIEKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTWAGSMLCMKRGARLVTCGSTSGVSTNMNLMQLFQQQLKIFGSFGCRMENMADAMQKMARGIVHPVIDTVVGFSD
IDTALKRMEGRDVFGKIILQID

Sequences:

>Translated_342_residues
MRALQLLDDRRLEITDIAPPPLPGMGEVTVRIKAVALNHIDVWGWRGMAFAKRKMPLVIGAEASGVVDAVGPGVSNLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVGGVHGFHLDGFACEAVNLPARLLVAAPPGVDAIGAAVAPVTFGTVEHMLFDN
AKLEPGETVLVQAGGSGIGTAAIQLAKKMGCTVITTVGSNDKIEKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTWAGSMLCMKRGARLVTCGSTSGVSTNMNLMQLFQQQLKIFGSFGCRMENMADAMQKMARGIVHPVIDTVVGFSD
IDTALKRMEGRDVFGKIILQID
>Mature_342_residues
MRALQLLDDRRLEITDIAPPPLPGMGEVTVRIKAVALNHIDVWGWRGMAFAKRKMPLVIGAEASGVVDAVGPGVSNLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVGGVHGFHLDGFACEAVNLPARLLVAAPPGVDAIGAAVAPVTFGTVEHMLFDN
AKLEPGETVLVQAGGSGIGTAAIQLAKKMGCTVITTVGSNDKIEKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTWAGSMLCMKRGARLVTCGSTSGVSTNMNLMQLFQQQLKIFGSFGCRMENMADAMQKMARGIVHPVIDTVVGFSD
IDTALKRMEGRDVFGKIILQID

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=346, Percent_Identity=27.4566473988439, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI22538444, Length=346, Percent_Identity=27.4566473988439, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI18379349, Length=337, Percent_Identity=25.2225519287834, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI24308257, Length=350, Percent_Identity=24.2857142857143, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI41872631, Length=213, Percent_Identity=30.0469483568075, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI194239674, Length=348, Percent_Identity=22.9885057471264, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13236495, Length=348, Percent_Identity=22.9885057471264, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI34577061, Length=267, Percent_Identity=31.0861423220974, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4501929, Length=351, Percent_Identity=28.7749287749288, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI28557745, Length=263, Percent_Identity=30.4182509505703, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4501933, Length=351, Percent_Identity=27.6353276353276, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI156627571, Length=289, Percent_Identity=30.1038062283737, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226059159, Length=231, Percent_Identity=27.7056277056277, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226059133, Length=231, Percent_Identity=27.7056277056277, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI262073058, Length=260, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI71743840, Length=260, Percent_Identity=29.2307692307692, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=265, Percent_Identity=32.0754716981132, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790045, Length=355, Percent_Identity=29.0140845070423, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788073, Length=332, Percent_Identity=26.8072289156627, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081918, Length=343, Percent_Identity=25.3644314868805, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787863, Length=200, Percent_Identity=34, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI226510992, Length=160, Percent_Identity=33.75, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788407, Length=217, Percent_Identity=29.4930875576037, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786518, Length=211, Percent_Identity=31.2796208530806, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=323, Percent_Identity=25.3869969040248, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=331, Percent_Identity=26.2839879154079, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=274, Percent_Identity=28.8321167883212, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=266, Percent_Identity=28.1954887218045, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562582, Length=321, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562878, Length=308, Percent_Identity=26.2987012987013, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=335, Percent_Identity=26.865671641791, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=26.8072289156627, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=332, Percent_Identity=26.5060240963855, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322619, Length=317, Percent_Identity=29.6529968454259, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319955, Length=317, Percent_Identity=29.3375394321767, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=23.7951807228916, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=24.5508982035928, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323099, Length=264, Percent_Identity=26.8939393939394, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581345, Length=226, Percent_Identity=27.8761061946903, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330659, Length=227, Percent_Identity=26.8722466960352, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920632, Length=227, Percent_Identity=26.8722466960352, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 36464; Mature: 36464

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALQLLDDRRLEITDIAPPPLPGMGEVTVRIKAVALNHIDVWGWRGMAFAKRKMPLVIG
CCCHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECEEECCCCCHHHHHCCCCEEEE
AEASGVVDAVGPGVSNLLPGQLVSIYGARTCGLCRACREGRDNLCEHVGGVHGFHLDGFA
CCCCCCHHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEE
CEAVNLPARLLVAAPPGVDAIGAAVAPVTFGTVEHMLFDNAKLEPGETVLVQAGGSGIGT
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIQLAKKMGCTVITTVGSNDKIEKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HHHHHHHHCCCEEEEEECCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWAGSMLCMKRGARLVTCGSTSGVSTNMNLMQLFQQQLKIFGSFGCRMENMADAM
HCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QKMARGIVHPVIDTVVGFSDIDTALKRMEGRDVFGKIILQID
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEEEEC
>Mature Secondary Structure
MRALQLLDDRRLEITDIAPPPLPGMGEVTVRIKAVALNHIDVWGWRGMAFAKRKMPLVIG
CCCHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEEECEEECCCCCHHHHHCCCCEEEE
AEASGVVDAVGPGVSNLLPGQLVSIYGARTCGLCRACREGRDNLCEHVGGVHGFHLDGFA
CCCCCCHHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEE
CEAVNLPARLLVAAPPGVDAIGAAVAPVTFGTVEHMLFDNAKLEPGETVLVQAGGSGIGT
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIQLAKKMGCTVITTVGSNDKIEKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HHHHHHHHCCCEEEEEECCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWAGSMLCMKRGARLVTCGSTSGVSTNMNLMQLFQQQLKIFGSFGCRMENMADAM
HCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QKMARGIVHPVIDTVVGFSDIDTALKRMEGRDVFGKIILQID
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]