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The map label for this gene is mtlR [H]

Identifier: 23100872

GI number: 23100872

Start: 3554416

End: 3556317

Strand: Reverse

Name: mtlR [H]

Synonym: OB3417

Alternate gene names: 23100872

Gene position: 3556317-3554416 (Counterclockwise)

Preceding gene: 23100873

Following gene: 23100871

Centisome position: 97.96

GC content: 37.7

Gene sequence:

>1902_bases
ATGTTATCTACGAGACAAAAACAATTACTTACCAAGCTTATAGAAACACATCAGTATATGACCGTGGACTTTTTGGCAAA
GTGGTTGGAAGTTAGCCCGAAAACGGTTCGCAATGATTTAGATACGTTAGCTAGCCTTCTTGATGAAATGGGTTGCTCTC
TCACACGAACTCCAGGAAAAGGTGTTGTTCTTCATGCCAATAGTGAAGTAAAAGAAGAACTTATGGAATCATTGGAATTA
GCGACGTCATTAGTCGATAAGAATGTCCAGCTTACCATGGTGAGCTTATATGTCTTAATGACAGAAAATGTAACGATTCA
AAAAATAGCTGACGAATTTTATCTCAGTCGATCTAGTGTTCATCAGATTCTTTTAGAAGTAGAAGAATTGCTTGATCCTT
ATAATTTACAGCTCACGAAGGAAGTAAGAAAAGGCCTGTTTATTCATGGTACAGAAAGAAGTAAGCGAAAAGCTGTATTT
TATTGGTTATCGAGTAAATGGGTAGATGTAGATGCGGTATGTAGCTGGCTTCCGATGGATATTAACGAACAACAGACCAT
TGCTAGTTGGATTTGTTCCTGTGAAAACGAAAGAGGCGTGATGTACAGTGAGGAATCCAAACGACATTTATCGTTATTCT
TCATTTGGTGGAAACACCGTGTGGATAGTGGTATATCCGTGTTTATTCCGAAGAAACATCGTATTCATAACCCAATTATT
GGTGAAGTGGATGACTATCTTAATCAAATGACTGGTGAACCGGAATTGATGGAGAACGAGAAGAATTTTATCCATCAGGT
TTTTGACCAACTCAAAGTGATTGCTTATAAATTTGAGGCAGATGATTTGGATCACTATAAGCGAGAGCACGCGTTCACAT
TGTATCTCATTCAGGAGATTTCCAAAATACTAGAAGTCAATCTAGCGTCAGATAAGAAATTAATGAATGACTTAATGTAC
CATGCAAAATCTGCGTTTTTACGAATGGAGCAAGGGGCAGAAATCGATAACCCTTATACCGAGGAAATTAAAATTCGCTA
TCGTGCCATTTATGAGATGGTACATCAGATTACGACGGATATGGGTTATGAAATGGTCGCTGCAGAAGTAGCTTATATAA
CGATGCATATTAGTTCTGCTTTTGAGCGAAGCGGCAATAAAAAATATTTACCCAATGTAATTGTCGTATGTACGACTGGG
CTAGCTACTTCTTCAATTTTAACAACGAAGTTAGAACATATTGAACCAGGATTTCATCTGGTGAAAGTTGTAAGTTCTCA
AGAAGTAGATGAGGAGTTAGCTTTAGATAATATTGATTTTGTTTTGACGACCAGTAAATTATCGATTGATGGTGCCGGTG
ATACGAAAATCTATCGTGTTAGCCCATTGTTATTGGATGACGAGAAAGCAAAAATTCAGCATGAAGCGCATAAAGTCGTA
AATCGAAAACAGCTGCAACGTTTTAATGAAGTGTACCAACATGCAACGTCGATTGTGCCGACCTTATTTGATGAACATGT
TCACTTTAGTAACACTAATAATTGGCATGAGGCTATAAGCCTTGCTGCTGCACCATTGTTAGAGGCTGGATATATCAAAC
AAGGGTATATACAGGAAATGATTATGTCTGTGGAGCGTAATGGGACGTATATGGTTTTTCTTCCAAAGATCGCATTCGTA
CATGCGAGCCCTGAGAACGTTATTAAGGAAGGGATAAGCATGACGGTTTTTGAAAACGACATGATATTTGGGTCGAAAAA
CCCGGAAGAAGTCAAAATCATTATCGTACTTGCCATTAAAGAATCACATAACCAAGACTTTTTACAACTTTATAGATATT
TAGAGAATCAAGCGGTTTTCGAAAAACTTATAGACAGCAACAATCAAGAGTGGAGGAAGTAA

Upstream 100 bases:

>100_bases
TATAAATAACAGCTCTGCTCTTTTTTTACCACAGTTGTGTTAATTTTCGTTCTTTAGGTAAATAAGAAGTAATAATAAAC
TAAGCTTAAAGGTGATGAAC

Downstream 100 bases:

>100_bases
TATTGAAGCAACTACGAAAAAATCATATATCTATACTAACAGAAGCAAAAGATTGGCGAGCTGCCATTGAGTTATCAGGA
CAATTACTTGTTCATTCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MLSTRQKQLLTKLIETHQYMTVDFLAKWLEVSPKTVRNDLDTLASLLDEMGCSLTRTPGKGVVLHANSEVKEELMESLEL
ATSLVDKNVQLTMVSLYVLMTENVTIQKIADEFYLSRSSVHQILLEVEELLDPYNLQLTKEVRKGLFIHGTERSKRKAVF
YWLSSKWVDVDAVCSWLPMDINEQQTIASWICSCENERGVMYSEESKRHLSLFFIWWKHRVDSGISVFIPKKHRIHNPII
GEVDDYLNQMTGEPELMENEKNFIHQVFDQLKVIAYKFEADDLDHYKREHAFTLYLIQEISKILEVNLASDKKLMNDLMY
HAKSAFLRMEQGAEIDNPYTEEIKIRYRAIYEMVHQITTDMGYEMVAAEVAYITMHISSAFERSGNKKYLPNVIVVCTTG
LATSSILTTKLEHIEPGFHLVKVVSSQEVDEELALDNIDFVLTTSKLSIDGAGDTKIYRVSPLLLDDEKAKIQHEAHKVV
NRKQLQRFNEVYQHATSIVPTLFDEHVHFSNTNNWHEAISLAAAPLLEAGYIKQGYIQEMIMSVERNGTYMVFLPKIAFV
HASPENVIKEGISMTVFENDMIFGSKNPEEVKIIIVLAIKESHNQDFLQLYRYLENQAVFEKLIDSNNQEWRK

Sequences:

>Translated_633_residues
MLSTRQKQLLTKLIETHQYMTVDFLAKWLEVSPKTVRNDLDTLASLLDEMGCSLTRTPGKGVVLHANSEVKEELMESLEL
ATSLVDKNVQLTMVSLYVLMTENVTIQKIADEFYLSRSSVHQILLEVEELLDPYNLQLTKEVRKGLFIHGTERSKRKAVF
YWLSSKWVDVDAVCSWLPMDINEQQTIASWICSCENERGVMYSEESKRHLSLFFIWWKHRVDSGISVFIPKKHRIHNPII
GEVDDYLNQMTGEPELMENEKNFIHQVFDQLKVIAYKFEADDLDHYKREHAFTLYLIQEISKILEVNLASDKKLMNDLMY
HAKSAFLRMEQGAEIDNPYTEEIKIRYRAIYEMVHQITTDMGYEMVAAEVAYITMHISSAFERSGNKKYLPNVIVVCTTG
LATSSILTTKLEHIEPGFHLVKVVSSQEVDEELALDNIDFVLTTSKLSIDGAGDTKIYRVSPLLLDDEKAKIQHEAHKVV
NRKQLQRFNEVYQHATSIVPTLFDEHVHFSNTNNWHEAISLAAAPLLEAGYIKQGYIQEMIMSVERNGTYMVFLPKIAFV
HASPENVIKEGISMTVFENDMIFGSKNPEEVKIIIVLAIKESHNQDFLQLYRYLENQAVFEKLIDSNNQEWRK
>Mature_633_residues
MLSTRQKQLLTKLIETHQYMTVDFLAKWLEVSPKTVRNDLDTLASLLDEMGCSLTRTPGKGVVLHANSEVKEELMESLEL
ATSLVDKNVQLTMVSLYVLMTENVTIQKIADEFYLSRSSVHQILLEVEELLDPYNLQLTKEVRKGLFIHGTERSKRKAVF
YWLSSKWVDVDAVCSWLPMDINEQQTIASWICSCENERGVMYSEESKRHLSLFFIWWKHRVDSGISVFIPKKHRIHNPII
GEVDDYLNQMTGEPELMENEKNFIHQVFDQLKVIAYKFEADDLDHYKREHAFTLYLIQEISKILEVNLASDKKLMNDLMY
HAKSAFLRMEQGAEIDNPYTEEIKIRYRAIYEMVHQITTDMGYEMVAAEVAYITMHISSAFERSGNKKYLPNVIVVCTTG
LATSSILTTKLEHIEPGFHLVKVVSSQEVDEELALDNIDFVLTTSKLSIDGAGDTKIYRVSPLLLDDEKAKIQHEAHKVV
NRKQLQRFNEVYQHATSIVPTLFDEHVHFSNTNNWHEAISLAAAPLLEAGYIKQGYIQEMIMSVERNGTYMVFLPKIAFV
HASPENVIKEGISMTVFENDMIFGSKNPEEVKIIIVLAIKESHNQDFLQLYRYLENQAVFEKLIDSNNQEWRK

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73107; Mature: 73107

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS51000 HTH_DEOR_2 ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTRQKQLLTKLIETHQYMTVDFLAKWLEVSPKTVRNDLDTLASLLDEMGCSLTRTPGK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCC
GVVLHANSEVKEELMESLELATSLVDKNVQLTMVSLYVLMTENVTIQKIADEFYLSRSSV
EEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHH
HQILLEVEELLDPYNLQLTKEVRKGLFIHGTERSKRKAVFYWLSSKWVDVDAVCSWLPMD
HHHHHHHHHHCCCCCCEEHHHHHCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCC
INEQQTIASWICSCENERGVMYSEESKRHLSLFFIWWKHRVDSGISVFIPKKHRIHNPII
CCCHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEHHCCCCCEEEECCCCCCCCCCC
GEVDDYLNQMTGEPELMENEKNFIHQVFDQLKVIAYKFEADDLDHYKREHAFTLYLIQEI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
SKILEVNLASDKKLMNDLMYHAKSAFLRMEQGAEIDNPYTEEIKIRYRAIYEMVHQITTD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MGYEMVAAEVAYITMHISSAFERSGNKKYLPNVIVVCTTGLATSSILTTKLEHIEPGFHL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHH
VKVVSSQEVDEELALDNIDFVLTTSKLSIDGAGDTKIYRVSPLLLDDEKAKIQHEAHKVV
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEECCEEECCHHHHHHHHHHHHH
NRKQLQRFNEVYQHATSIVPTLFDEHVHFSNTNNWHEAISLAAAPLLEAGYIKQGYIQEM
HHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
IMSVERNGTYMVFLPKIAFVHASPENVIKEGISMTVFENDMIFGSKNPEEVKIIIVLAIK
HHHHHCCCEEEEEECCEEEEECCHHHHHHCCCEEEEEECCEEECCCCCCCEEEEEEEEEE
ESHNQDFLQLYRYLENQAVFEKLIDSNNQEWRK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MLSTRQKQLLTKLIETHQYMTVDFLAKWLEVSPKTVRNDLDTLASLLDEMGCSLTRTPGK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCC
GVVLHANSEVKEELMESLELATSLVDKNVQLTMVSLYVLMTENVTIQKIADEFYLSRSSV
EEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHH
HQILLEVEELLDPYNLQLTKEVRKGLFIHGTERSKRKAVFYWLSSKWVDVDAVCSWLPMD
HHHHHHHHHHCCCCCCEEHHHHHCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCC
INEQQTIASWICSCENERGVMYSEESKRHLSLFFIWWKHRVDSGISVFIPKKHRIHNPII
CCCHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEHHCCCCCEEEECCCCCCCCCCC
GEVDDYLNQMTGEPELMENEKNFIHQVFDQLKVIAYKFEADDLDHYKREHAFTLYLIQEI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
SKILEVNLASDKKLMNDLMYHAKSAFLRMEQGAEIDNPYTEEIKIRYRAIYEMVHQITTD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MGYEMVAAEVAYITMHISSAFERSGNKKYLPNVIVVCTTGLATSSILTTKLEHIEPGFHL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHH
VKVVSSQEVDEELALDNIDFVLTTSKLSIDGAGDTKIYRVSPLLLDDEKAKIQHEAHKVV
HHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEECCEEECCHHHHHHHHHHHHH
NRKQLQRFNEVYQHATSIVPTLFDEHVHFSNTNNWHEAISLAAAPLLEAGYIKQGYIQEM
HHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
IMSVERNGTYMVFLPKIAFVHASPENVIKEGISMTVFENDMIFGSKNPEEVKIIIVLAIK
HHHHHCCCEEEEEECCEEEEECCHHHHHHCCCEEEEEECCEEECCCCCCCEEEEEEEEEE
ESHNQDFLQLYRYLENQAVFEKLIDSNNQEWRK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]