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The map label for this gene is rlmH

Identifier: 23100834

GI number: 23100834

Start: 3516702

End: 3517181

Strand: Reverse

Name: rlmH

Synonym: OB3379

Alternate gene names: 23100834

Gene position: 3517181-3516702 (Counterclockwise)

Preceding gene: 23100837

Following gene: 23100833

Centisome position: 96.88

GC content: 41.67

Gene sequence:

>480_bases
ATGAATATAACGATTGTATCGGTAGGTAAATTAAAGGAAAAGTACTTGAAGCAAGGAATTGATGAATATAAAAAACGTTT
AAATGCATACGCGAAAGTGTCGATAATCGAGGTAGCAGATGAAAAAGCACCAGAAACCATGAGCGAGGCGGAAATGAAAG
AGGTCAAGCGCAAAGAGGGCGAACGAATTCTATCTTCTATCGCACCCGATGCGTTTGTGATTACTTTGGAGATTGAAGGG
AAAATGCTAGGGTCTGAACAGCTAGCGAAGAAGCTGGACGAGCTTGCGACGTACGGGAAAAGCAAAGTCGTATTTGTGAT
TGGTGGATCACTTGGGATAAGTCAGGACGTGCAGCGGCGAAGTGATTTAGCATTGTCGTTTTCCAAGATGACATTTCCAC
ATCAGTTAATGCGGTTGGTATTGATTGAGCAGGTTTATCGTAGTTTTCGGATTAATAGGGGTGAACCATATCATAAATAA

Upstream 100 bases:

>100_bases
GGTAGGGAATTATAGTATTATCTTAAAAGGTGAATAGAATTATTATTTGATTGTCATATGGTAAACTAAAGGAAAACATG
CGTCGAAAAGGAAGATTTGT

Downstream 100 bases:

>100_bases
ATGAGGTTTTTTGTATTTAATATCGAATAAACAAAATATAAATGTTTAGAATAGAGGGATAGTAATTGTCTAAAATAAAT
GAAATTCAAAATAAAATTCA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNITIVSVGKLKEKYLKQGIDEYKKRLNAYAKVSIIEVADEKAPETMSEAEMKEVKRKEGERILSSIAPDAFVITLEIEG
KMLGSEQLAKKLDELATYGKSKVVFVIGGSLGISQDVQRRSDLALSFSKMTFPHQLMRLVLIEQVYRSFRINRGEPYHK

Sequences:

>Translated_159_residues
MNITIVSVGKLKEKYLKQGIDEYKKRLNAYAKVSIIEVADEKAPETMSEAEMKEVKRKEGERILSSIAPDAFVITLEIEG
KMLGSEQLAKKLDELATYGKSKVVFVIGGSLGISQDVQRRSDLALSFSKMTFPHQLMRLVLIEQVYRSFRINRGEPYHK
>Mature_159_residues
MNITIVSVGKLKEKYLKQGIDEYKKRLNAYAKVSIIEVADEKAPETMSEAEMKEVKRKEGERILSSIAPDAFVITLEIEG
KMLGSEQLAKKLDELATYGKSKVVFVIGGSLGISQDVQRRSDLALSFSKMTFPHQLMRLVLIEQVYRSFRINRGEPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=159, Percent_Identity=30.188679245283, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_OCEIH (Q8EL52)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_694301.1
- ProteinModelPortal:   Q8EL52
- SMR:   Q8EL52
- GeneID:   1016294
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3379
- NMPDR:   fig|221109.1.peg.3383
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- BioCyc:   OIHE221109:OB3379-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR016051
- InterPro:   IPR003742
- PIRSF:   PIRSF004505
- TIGRFAMs:   TIGR00246

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 18040; Mature: 18040

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITIVSVGKLKEKYLKQGIDEYKKRLNAYAKVSIIEVADEKAPETMSEAEMKEVKRKEG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
ERILSSIAPDAFVITLEIEGKMLGSEQLAKKLDELATYGKSKVVFVIGGSLGISQDVQRR
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
SDLALSFSKMTFPHQLMRLVLIEQVYRSFRINRGEPYHK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNITIVSVGKLKEKYLKQGIDEYKKRLNAYAKVSIIEVADEKAPETMSEAEMKEVKRKEG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
ERILSSIAPDAFVITLEIEGKMLGSEQLAKKLDELATYGKSKVVFVIGGSLGISQDVQRR
HHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
SDLALSFSKMTFPHQLMRLVLIEQVYRSFRINRGEPYHK
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376