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The map label for this gene is sorA [H]

Identifier: 23100829

GI number: 23100829

Start: 3509174

End: 3509986

Strand: Reverse

Name: sorA [H]

Synonym: OB3374

Alternate gene names: 23100829

Gene position: 3509986-3509174 (Counterclockwise)

Preceding gene: 23100830

Following gene: 23100828

Centisome position: 96.68

GC content: 41.45

Gene sequence:

>813_bases
ATGATTATGGAATTAACTATTATTCAAATAATATTAATTATTATTGTAGCATTTTTAGCTGGTGTAGAAGGAATCTTGGA
TGAATTCCACTTCCATCAGCCAATCATTGCCTGTACACTAATCGGTTTAGTTACAGGAGAAGTAGTACCTTGTCTTATCT
TAGGTGGTACCTTACAATTAATCGCTTTAGGTTGGGCGAACATTGGAGCCGCTGTAGCTCCGGATGCTGCACTAGCATCT
ATTGCATCGGCAATTATACTCGTTTTAGGTGGCCAGGGAGAATCTGGTGTATCTTCTGCAATCGCAATCGCAGTACCACT
TGCAGTTGCAGGTCTATTATTAACAATCATCGTTCGAACGATTGCAACCGGTTTGGTCCATTTAATGGATGCCGCGGCTA
AAGAAGGAAATATACGAAGGATCGACTTTTGGCATATTGTAGCGATTTGTATGCAAGGGTTGCGTATCGCAATTCCAGCC
GCGTTAATTTTGGCAATTGGTGCAGGTCCGGTTAGAGATTTACTTCAATCTATGCCTTCTTGGTTAACAGACGGTCTAGC
AGTCGGCGGTGGAATGGTAGTAGCTGTTGGTTATGCAATGGTTATTAACATGATGGCGACAAAAGAAGTATGGCCTTTCT
TTGCAATTGGTTTCGTATTAGCTACTATTCCATCTATTACTCTAATGGGTCTTGGTGGTATCGGTGTGGCTCTTGCATTG
ATTTATTTAGCACTTACAAAACAAGGCGGTTCTGGTAATGGTGGAAACGGAAACACTGGTGATCCGCTAGGTGAAATCAT
AGATAACTACTAA

Upstream 100 bases:

>100_bases
GAACGATTCCAGAGGTAATATGGATGAGATTATGAGAAGGGCTCAGTCAGAGCTAGATAGACAGAGATAATCCTAATCAT
CAGTAAAAAAAGGAGGATTA

Downstream 100 bases:

>100_bases
AAAGGAGGGACTAAAAATGGCTCGAGAAGAATTGAAATTAACAAAAAGAGATCGGATTGCGATTTGGTGGCGATCCACGT
TCATTCAGGGTTCTTGGAAC

Product: PTS system mannose-specific enzyme II C component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIMELTIIQIILIIIVAFLAGVEGILDEFHFHQPIIACTLIGLVTGEVVPCLILGGTLQLIALGWANIGAAVAPDAALAS
IASAIILVLGGQGESGVSSAIAIAVPLAVAGLLLTIIVRTIATGLVHLMDAAAKEGNIRRIDFWHIVAICMQGLRIAIPA
ALILAIGAGPVRDLLQSMPSWLTDGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATIPSITLMGLGGIGVALAL
IYLALTKQGGSGNGGNGNTGDPLGEIIDNY

Sequences:

>Translated_270_residues
MIMELTIIQIILIIIVAFLAGVEGILDEFHFHQPIIACTLIGLVTGEVVPCLILGGTLQLIALGWANIGAAVAPDAALAS
IASAIILVLGGQGESGVSSAIAIAVPLAVAGLLLTIIVRTIATGLVHLMDAAAKEGNIRRIDFWHIVAICMQGLRIAIPA
ALILAIGAGPVRDLLQSMPSWLTDGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATIPSITLMGLGGIGVALAL
IYLALTKQGGSGNGGNGNTGDPLGEIIDNY
>Mature_270_residues
MIMELTIIQIILIIIVAFLAGVEGILDEFHFHQPIIACTLIGLVTGEVVPCLILGGTLQLIALGWANIGAAVAPDAALAS
IASAIILVLGGQGESGVSSAIAIAVPLAVAGLLLTIIVRTIATGLVHLMDAAAKEGNIRRIDFWHIVAICMQGLRIAIPA
ALILAIGAGPVRDLLQSMPSWLTDGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATIPSITLMGLGGIGVALAL
IYLALTKQGGSGNGGNGNTGDPLGEIIDNY

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=247, Percent_Identity=49.7975708502024, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1789528, Length=251, Percent_Identity=24.7011952191235, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27576; Mature: 27576

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMELTIIQIILIIIVAFLAGVEGILDEFHFHQPIIACTLIGLVTGEVVPCLILGGTLQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
IALGWANIGAAVAPDAALASIASAIILVLGGQGESGVSSAIAIAVPLAVAGLLLTIIVRT
HHHHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IATGLVHLMDAAAKEGNIRRIDFWHIVAICMQGLRIAIPAALILAIGAGPVRDLLQSMPS
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHH
WLTDGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATIPSITLMGLGGIGVALAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYLALTKQGGSGNGGNGNTGDPLGEIIDNY
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MIMELTIIQIILIIIVAFLAGVEGILDEFHFHQPIIACTLIGLVTGEVVPCLILGGTLQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
IALGWANIGAAVAPDAALASIASAIILVLGGQGESGVSSAIAIAVPLAVAGLLLTIIVRT
HHHHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IATGLVHLMDAAAKEGNIRRIDFWHIVAICMQGLRIAIPAALILAIGAGPVRDLLQSMPS
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHH
WLTDGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATIPSITLMGLGGIGVALAL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYLALTKQGGSGNGGNGNTGDPLGEIIDNY
HHHHHHCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]