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The map label for this gene is bdhA [H]

Identifier: 23100808

GI number: 23100808

Start: 3488621

End: 3489676

Strand: Reverse

Name: bdhA [H]

Synonym: OB3353

Alternate gene names: 23100808

Gene position: 3489676-3488621 (Counterclockwise)

Preceding gene: 23100809

Following gene: 23100805

Centisome position: 96.12

GC content: 42.71

Gene sequence:

>1056_bases
ATGAAGGCAGCAGTTTGGTATGGTAAACACGATATTCGTGTAGAGAATAAGGAAGAACCTATAATTAAACCTGGAAAGGT
TAAAATAAAAGTAGCATGGACAGGCATTTGTGGAAGTGACCTGCATGCTTATCACGGCGCTGAGGGAGTCGTTCAAGTTG
GCGAACCTCATCCTGTAACTGGTGAAATGGCACCATTGACGCTTGGGCATGAGTTTTCTGGTGTAATTCATGAAATTGGT
GAAGGTGTAAGCGGTTTATCTGTTGGAGATCGTGTAGCGATTGAGCCGGCTATTAAGTGTGGCAAGTGTGAGAATTGTGT
ACGAGGAAACTACAACTTGTGTGAACACAATGGCTTTGTTGGCTTACAATCTGACGGTGCTTTTGCTGAGTATGCAATTG
TTGATCCACATATGGTTCACAAGCTTCCAGATAATATATCGTTTGAAGAAGCTACAGCAATTGAGCCTACAGCTGTGTCT
TTCCACGCGCTTAAATTAAGCAATATGAAAGCAGGCGATACGGTAGCGGTCTTTGGTGTTGGCCCAATTGGTCTTACGGC
GATTCTATGTGCGAAGGCAGCTGGTGCGTCTCGTATTTATGCGATTGATGTTTCCAATGAGCGTCTTGAGATGGCTCAAA
AGCTTGGCGCAACTACGGTTATTAATGCGATAGAAGAGAATGCGGCAGAAAAGATATATGCTGAAACAGGAAGTGGCGTT
ACTATCGCATTTGATTGTGCAGGAGCTGAAGCGACTGTGAACAGTGCAATTGATTCACTTGCTAAAGGCGGACAACTTGT
CATTGTGTCCATTATTCCAGAACCGATCAAAGTAAATCTTTTGCAGGCGAACTTAAAAGAAATAAACATTCTTGCAACTA
TCGGTTACAGAGATGTGTATAAAGACGTTATTGCTATGGTGGAATCAGGACAGCTGGATCTTAAACCGATCATCACTAAA
AAAATCGGTTTGGATGATATTATCGAAGAAGGCTTCCACGCCCTTACAAATGATAAGAGCCAAGCAAAAATTCTTGTGAG
CCCAACAGGGGTTTAA

Upstream 100 bases:

>100_bases
GCGATGTTAATCGTTTTAAAATTATATACGCATAGAGATGAATGGAGAAAGGGTTTTCATTTATCACTATACAAAATCTA
TATAGGGGGTATTTAGTATT

Downstream 100 bases:

>100_bases
TCCTTACAGAATTTATTCGTAGCTTTGAATGAAGACATAACTATATTAGAAAATAGTAGGGCTATCCTTGTTGGAGGATG
GTCCTATACTTTGTTGTTAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKAAVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEMAPLTLGHEFSGVIHEIG
EGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFVGLQSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVS
FHALKLSNMKAGDTVAVFGVGPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGV
TIAFDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVYKDVIAMVESGQLDLKPIITK
KIGLDDIIEEGFHALTNDKSQAKILVSPTGV

Sequences:

>Translated_351_residues
MKAAVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEMAPLTLGHEFSGVIHEIG
EGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFVGLQSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVS
FHALKLSNMKAGDTVAVFGVGPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGV
TIAFDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVYKDVIAMVESGQLDLKPIITK
KIGLDDIIEEGFHALTNDKSQAKILVSPTGV
>Mature_351_residues
MKAAVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEMAPLTLGHEFSGVIHEIG
EGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFVGLQSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVS
FHALKLSNMKAGDTVAVFGVGPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGV
TIAFDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVYKDVIAMVESGQLDLKPIITK
KIGLDDIIEEGFHALTNDKSQAKILVSPTGV

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=330, Percent_Identity=34.2424242424242, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI4501929, Length=378, Percent_Identity=28.3068783068783, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI156523966, Length=357, Percent_Identity=27.1708683473389, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4501939, Length=357, Percent_Identity=27.1708683473389, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4501933, Length=374, Percent_Identity=28.0748663101604, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI262073058, Length=376, Percent_Identity=27.3936170212766, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI71743840, Length=376, Percent_Identity=27.3936170212766, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI34577061, Length=374, Percent_Identity=27.5401069518717, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI71565152, Length=381, Percent_Identity=26.246719160105, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI71565154, Length=291, Percent_Identity=29.2096219931272, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI194239674, Length=276, Percent_Identity=26.8115942028986, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI13236495, Length=276, Percent_Identity=26.8115942028986, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788073, Length=331, Percent_Identity=33.5347432024169, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1790045, Length=321, Percent_Identity=34.2679127725857, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1787863, Length=348, Percent_Identity=29.0229885057471, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788407, Length=351, Percent_Identity=30.7692307692308, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1788075, Length=366, Percent_Identity=27.0491803278689, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=32.0987654320988, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082125, Length=262, Percent_Identity=32.4427480916031, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790718, Length=321, Percent_Identity=28.0373831775701, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI226510992, Length=280, Percent_Identity=30, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786825, Length=282, Percent_Identity=32.2695035460993, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786552, Length=354, Percent_Identity=30.5084745762712, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082401, Length=133, Percent_Identity=34.5864661654135, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=336, Percent_Identity=34.5238095238095, Blast_Score=207, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17562878, Length=335, Percent_Identity=36.7164179104478, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI25146526, Length=292, Percent_Identity=29.4520547945205, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71997431, Length=294, Percent_Identity=29.2517006802721, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17565904, Length=273, Percent_Identity=27.4725274725275, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71988145, Length=283, Percent_Identity=28.6219081272085, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=280, Percent_Identity=26.4285714285714, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=300, Percent_Identity=25.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=376, Percent_Identity=33.2446808510638, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319257, Length=379, Percent_Identity=32.9815303430079, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319955, Length=329, Percent_Identity=32.5227963525836, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6322619, Length=329, Percent_Identity=32.5227963525836, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6323099, Length=336, Percent_Identity=36.3095238095238, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320033, Length=384, Percent_Identity=27.8645833333333, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=338, Percent_Identity=28.9940828402367, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=28.7833827893175, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=29.2899408284024, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6323980, Length=278, Percent_Identity=28.7769784172662, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=351, Percent_Identity=27.3504273504274, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737897, Length=332, Percent_Identity=34.9397590361446, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI17137530, Length=322, Percent_Identity=34.7826086956522, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI45551930, Length=335, Percent_Identity=26.2686567164179, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI221457811, Length=335, Percent_Identity=26.2686567164179, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45550770, Length=335, Percent_Identity=26.2686567164179, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17737895, Length=301, Percent_Identity=29.5681063122924, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 37116; Mature: 37116

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVT
CCCEEEECCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCHHHCCCCCEEECCCCCCCC
GEMAPLTLGHEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFV
CCCCEEEECCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCEECCCCEE
GLQSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHALKLSNMKAGDTVAVFGV
EECCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEE
GPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGV
CHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCE
TIAFDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVY
EEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECHHHHH
KDVIAMVESGQLDLKPIITKKIGLDDIIEEGFHALTNDKSQAKILVSPTGV
HHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKAAVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVT
CCCEEEECCEEEEECCCCCCCCCCCEEEEEEEEEECCCCCCHHHCCCCCEEECCCCCCCC
GEMAPLTLGHEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFV
CCCCEEEECCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCEECCCCEE
GLQSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHALKLSNMKAGDTVAVFGV
EECCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEE
GPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGV
CHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCE
TIAFDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVY
EEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEEECHHHHH
KDVIAMVESGQLDLKPIITKKIGLDDIIEEGFHALTNDKSQAKILVSPTGV
HHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]