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The map label for this gene is yqiR [H]

Identifier: 23100084

GI number: 23100084

Start: 2696035

End: 2697435

Strand: Reverse

Name: yqiR [H]

Synonym: OB2629

Alternate gene names: 23100084

Gene position: 2697435-2696035 (Counterclockwise)

Preceding gene: 23100085

Following gene: 23100082

Centisome position: 74.3

GC content: 33.83

Gene sequence:

>1401_bases
ATGAAGCAACTCCCTAAAGAGTGGATAGAACAAATTATTACATTATTAAATGAACGTATTGTCGTAGTAGATGCAAAGGG
AATAGTGGTATATATGGACCAAGCGTATTGTGATTTTATTGAACGCCCTGTGAACCAATGTATAGGTTATCATGTAAAGG
ATGTTATAGAAAACACGAGAATGCACGTAATTGTGAAGACAGGTAAAATAGAGCTAGAAGATTTTCATCCTATTAATGGA
AGTGTAATGATAGCAAATCGATTTCCGATAGTAGTTGATGATGAGATAGTTGGTGCAGTTGGAACAGTGATGTTTCCAAC
GCCAGAAAATCTTCGTGATTTTAAAAATAAGATTCAGCAACTCGTCACTGACTTAAGCTATTATAGAGATAAAGTGAACA
ATGAATTAAGAAGTAAATATACGTTTAAGGATCTAATAGGAAATAGTCAAGAATTCGTTCACTTAAAAGAATTCGCAGAA
ACGGTTGCTGGTAATGATTCCTCTGTTCTTATTACCGGTGAGTCTGGAACAGGAAAGGAACTATTTGCAAACGCTATTCA
TAACAGCAGTTTACGTGAACAGCATCCATTTTTACCGATTAACTGTTCAGCTATCCCAGAAGAATTATTTGAATCGGAAC
TATTTGGTTATTCAGAAGGGGCATTTACAGATGCAAAAAAAGGTGGAAAGAAAGGTCTCTTCGAAATTGCGCATAACGGA
ACTATATTTTTAGATGAGATTGGTGAATTACCATTATCGATGCAAAGCAAACTGCTGAGAGTTTTACAAGAAAGAGAAAT
ACAGCCAATTGGAGCTCAAAAATATATCTCAATTAATGTACGGATAATTGTTGCTACTAACCGTAACCTATTAAAAATGG
TAGAGAATGGAGAATTTAGAGAAGATCTCTATTATCGGTTGAATGTGATTCATATTGATATACCGCCTTTAAGAAAAAGG
AAGGAAGATATCAAACAGACTGCATATCAATTACTAAGAAAATTAGAGCATAAATTTTACCGTTCGGATGTAATGATTTC
GAAGGAAGTCATCAAACAATTAGAAATGCATCATTGGCCAGGCAATGTTCGTGAACTAGAGAATGTACTAGAACGAGCGA
TTAATATGTTGAAAGAGAATACTATTCTACTACAGCATTTGCCACTCTATATTCGTGATATAATTTTAGAAGAAAGAATG
AATATCGAACAAACAGAAAAAAATAGAGGTAATGAAATAGTCTATTTAAAAAAGATGAAAGAAGTAATAGCGGATGCAGA
AAAGCAAGCAATACAAAATGCTTTATCGCACACGAAAGGCAATAAGCTAGAAGCAGCTAAACTTTTAGGGATAGGTAAAA
CAAGTCTATATGATAAGTGTCACCAATATAGTATTAACTAA

Upstream 100 bases:

>100_bases
GCTTTAGCTGCAATGGGGATATATTAAGAATAGCTTTTTAAATTACTAAATTTAATTATATACTTGTAATAAATATTTAA
TTCTGGAGGGTATAATTGTT

Downstream 100 bases:

>100_bases
TAAAAATCCCCCTTTTGATAGATTATAAGGGGGATTTTTCATATATTTAGTTGGCAGGGTCTTTTCAATGTTTTACGGGA
CTCTTTGCTTCAATCCCTTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKQLPKEWIEQIITLLNERIVVVDAKGIVVYMDQAYCDFIERPVNQCIGYHVKDVIENTRMHVIVKTGKIELEDFHPING
SVMIANRFPIVVDDEIVGAVGTVMFPTPENLRDFKNKIQQLVTDLSYYRDKVNNELRSKYTFKDLIGNSQEFVHLKEFAE
TVAGNDSSVLITGESGTGKELFANAIHNSSLREQHPFLPINCSAIPEELFESELFGYSEGAFTDAKKGGKKGLFEIAHNG
TIFLDEIGELPLSMQSKLLRVLQEREIQPIGAQKYISINVRIIVATNRNLLKMVENGEFREDLYYRLNVIHIDIPPLRKR
KEDIKQTAYQLLRKLEHKFYRSDVMISKEVIKQLEMHHWPGNVRELENVLERAINMLKENTILLQHLPLYIRDIILEERM
NIEQTEKNRGNEIVYLKKMKEVIADAEKQAIQNALSHTKGNKLEAAKLLGIGKTSLYDKCHQYSIN

Sequences:

>Translated_466_residues
MKQLPKEWIEQIITLLNERIVVVDAKGIVVYMDQAYCDFIERPVNQCIGYHVKDVIENTRMHVIVKTGKIELEDFHPING
SVMIANRFPIVVDDEIVGAVGTVMFPTPENLRDFKNKIQQLVTDLSYYRDKVNNELRSKYTFKDLIGNSQEFVHLKEFAE
TVAGNDSSVLITGESGTGKELFANAIHNSSLREQHPFLPINCSAIPEELFESELFGYSEGAFTDAKKGGKKGLFEIAHNG
TIFLDEIGELPLSMQSKLLRVLQEREIQPIGAQKYISINVRIIVATNRNLLKMVENGEFREDLYYRLNVIHIDIPPLRKR
KEDIKQTAYQLLRKLEHKFYRSDVMISKEVIKQLEMHHWPGNVRELENVLERAINMLKENTILLQHLPLYIRDIILEERM
NIEQTEKNRGNEIVYLKKMKEVIADAEKQAIQNALSHTKGNKLEAAKLLGIGKTSLYDKCHQYSIN
>Mature_466_residues
MKQLPKEWIEQIITLLNERIVVVDAKGIVVYMDQAYCDFIERPVNQCIGYHVKDVIENTRMHVIVKTGKIELEDFHPING
SVMIANRFPIVVDDEIVGAVGTVMFPTPENLRDFKNKIQQLVTDLSYYRDKVNNELRSKYTFKDLIGNSQEFVHLKEFAE
TVAGNDSSVLITGESGTGKELFANAIHNSSLREQHPFLPINCSAIPEELFESELFGYSEGAFTDAKKGGKKGLFEIAHNG
TIFLDEIGELPLSMQSKLLRVLQEREIQPIGAQKYISINVRIIVATNRNLLKMVENGEFREDLYYRLNVIHIDIPPLRKR
KEDIKQTAYQLLRKLEHKFYRSDVMISKEVIKQLEMHHWPGNVRELENVLERAINMLKENTILLQHLPLYIRDIILEERM
NIEQTEKNRGNEIVYLKKMKEVIADAEKQAIQNALSHTKGNKLEAAKLLGIGKTSLYDKCHQYSIN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=335, Percent_Identity=42.9850746268657, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI87082117, Length=378, Percent_Identity=40.4761904761905, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=43.0340557275542, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788905, Length=331, Percent_Identity=43.202416918429, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1790437, Length=317, Percent_Identity=42.2712933753943, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1789087, Length=328, Percent_Identity=42.6829268292683, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1786524, Length=399, Percent_Identity=35.0877192982456, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1790299, Length=370, Percent_Identity=35.4054054054054, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=45.7264957264957, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1787583, Length=458, Percent_Identity=29.0393013100437, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=37.3040752351097, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87081858, Length=330, Percent_Identity=32.4242424242424, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1789828, Length=233, Percent_Identity=31.7596566523605, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53678; Mature: 53678

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLPKEWIEQIITLLNERIVVVDAKGIVVYMDQAYCDFIERPVNQCIGYHVKDVIENTR
CCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHCCCC
MHVIVKTGKIELEDFHPINGSVMIANRFPIVVDDEIVGAVGTVMFPTPENLRDFKNKIQQ
EEEEEEECEEEECCCCCCCCEEEEECCCCEEECCHHHHHHCEEECCCCHHHHHHHHHHHH
LVTDLSYYRDKVNNELRSKYTFKDLIGNSQEFVHLKEFAETVAGNDSSVLITGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
LFANAIHNSSLREQHPFLPINCSAIPEELFESELFGYSEGAFTDAKKGGKKGLFEIAHNG
HHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEECCC
TIFLDEIGELPLSMQSKLLRVLQEREIQPIGAQKYISINVRIIVATNRNLLKMVENGEFR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHCCCHH
EDLYYRLNVIHIDIPPLRKRKEDIKQTAYQLLRKLEHKFYRSDVMISKEVIKQLEMHHWP
HHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNVRELENVLERAINMLKENTILLQHLPLYIRDIILEERMNIEQTEKNRGNEIVYLKKMK
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEHHHHH
EVIADAEKQAIQNALSHTKGNKLEAAKLLGIGKTSLYDKCHQYSIN
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKQLPKEWIEQIITLLNERIVVVDAKGIVVYMDQAYCDFIERPVNQCIGYHVKDVIENTR
CCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHCHHHHHHHCCCC
MHVIVKTGKIELEDFHPINGSVMIANRFPIVVDDEIVGAVGTVMFPTPENLRDFKNKIQQ
EEEEEEECEEEECCCCCCCCEEEEECCCCEEECCHHHHHHCEEECCCCHHHHHHHHHHHH
LVTDLSYYRDKVNNELRSKYTFKDLIGNSQEFVHLKEFAETVAGNDSSVLITGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHH
LFANAIHNSSLREQHPFLPINCSAIPEELFESELFGYSEGAFTDAKKGGKKGLFEIAHNG
HHHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEECCC
TIFLDEIGELPLSMQSKLLRVLQEREIQPIGAQKYISINVRIIVATNRNLLKMVENGEFR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHCCCHH
EDLYYRLNVIHIDIPPLRKRKEDIKQTAYQLLRKLEHKFYRSDVMISKEVIKQLEMHHWP
HHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNVRELENVLERAINMLKENTILLQHLPLYIRDIILEERMNIEQTEKNRGNEIVYLKKMK
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEHHHHH
EVIADAEKQAIQNALSHTKGNKLEAAKLLGIGKTSLYDKCHQYSIN
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]