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The map label for this gene is sipW [H]

Identifier: 23099981

GI number: 23099981

Start: 2581133

End: 2581726

Strand: Reverse

Name: sipW [H]

Synonym: OB2526

Alternate gene names: 23099981

Gene position: 2581726-2581133 (Counterclockwise)

Preceding gene: 23099982

Following gene: 23099980

Centisome position: 71.11

GC content: 37.04

Gene sequence:

>594_bases
ATGAAAATCACAAAAAAAAGGCTGTTAAAATGGGGAAGTAATCTAGTATCATTTGTACTTTTCCTTGGTTTAGTTACGAT
GGCAACTATCGTAATTACAACGAAAGCAAGCGGTGGAGAACCAGAACTATTTGGGCTTCAATTTAAAACGGTACTATCTG
GTTCAATGGAGCCGGGTATTCAAACAGGATCTGTCATTGCTGTAGAAACGGGTGGGGATATGACTCGTTTTCAAGAAGAT
GATGTCATTACATTTATGGAAGAAGATTCAAAACTTGTCACACACCGAATTACAGAAGTGTTAAACAATGGGGAACATAT
TATGTACGAAACAAAAGGAGATAACAATAATGCAGCAGATATAAATCCTGTTTTTGCAGAAAATGTTGTCGCTGAATATA
CGGGTTTTACAGTACCGTACTTAGGATACCTTGTTAGCTTTGCACAAACACAAAACGGAGCTTTTCTATTACTAATACCT
GGTATATTACTTTTGGGGTATGCGGTCATCACCATTTGGCAAGGATTACGTGAATTAGAAAGAAATCAGAAAGCATTTCA
CGATGACAAAGAAGATAAACAAATCGCCACGTGA

Upstream 100 bases:

>100_bases
CAGAAGAAATAGAGACAATACCTGAAACGAATCCAGAGATTGATGAAAAAGAAGAGCAATCAGAAGCAGAAAAATCAGGT
GAAAGCGAGGAGGACGATCA

Downstream 100 bases:

>100_bases
TTGTATGAGCATAAAGTGGAGGTGAGGAAATGAAGAAAAATATCCTTATTATTGTCTGTTTTAGTATTATCGTATCATTA
ATTTACCCTTATCATTCTTA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKITKKRLLKWGSNLVSFVLFLGLVTMATIVITTKASGGEPELFGLQFKTVLSGSMEPGIQTGSVIAVETGGDMTRFQED
DVITFMEEDSKLVTHRITEVLNNGEHIMYETKGDNNNAADINPVFAENVVAEYTGFTVPYLGYLVSFAQTQNGAFLLLIP
GILLLGYAVITIWQGLRELERNQKAFHDDKEDKQIAT

Sequences:

>Translated_197_residues
MKITKKRLLKWGSNLVSFVLFLGLVTMATIVITTKASGGEPELFGLQFKTVLSGSMEPGIQTGSVIAVETGGDMTRFQED
DVITFMEEDSKLVTHRITEVLNNGEHIMYETKGDNNNAADINPVFAENVVAEYTGFTVPYLGYLVSFAQTQNGAFLLLIP
GILLLGYAVITIWQGLRELERNQKAFHDDKEDKQIAT
>Mature_197_residues
MKITKKRLLKWGSNLVSFVLFLGLVTMATIVITTKASGGEPELFGLQFKTVLSGSMEPGIQTGSVIAVETGGDMTRFQED
DVITFMEEDSKLVTHRITEVLNNGEHIMYETKGDNNNAADINPVFAENVVAEYTGFTVPYLGYLVSFAQTQNGAFLLLIP
GILLLGYAVITIWQGLRELERNQKAFHDDKEDKQIAT

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR001733 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21782; Mature: 21782

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITKKRLLKWGSNLVSFVLFLGLVTMATIVITTKASGGEPELFGLQFKTVLSGSMEPGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEHHHHHHHHCCCCCCCC
QTGSVIAVETGGDMTRFQEDDVITFMEEDSKLVTHRITEVLNNGEHIMYETKGDNNNAAD
CCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
INPVFAENVVAEYTGFTVPYLGYLVSFAQTQNGAFLLLIPGILLLGYAVITIWQGLRELE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNQKAFHDDKEDKQIAT
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKITKKRLLKWGSNLVSFVLFLGLVTMATIVITTKASGGEPELFGLQFKTVLSGSMEPGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEHHHHHHHHCCCCCCCC
QTGSVIAVETGGDMTRFQEDDVITFMEEDSKLVTHRITEVLNNGEHIMYETKGDNNNAAD
CCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
INPVFAENVVAEYTGFTVPYLGYLVSFAQTQNGAFLLLIPGILLLGYAVITIWQGLRELE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
RNQKAFHDDKEDKQIAT
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9823656 [H]