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The map label for this gene is secA

Identifier: 23099951

GI number: 23099951

Start: 2554822

End: 2557338

Strand: Reverse

Name: secA

Synonym: OB2496

Alternate gene names: 23099951

Gene position: 2557338-2554822 (Counterclockwise)

Preceding gene: 23099952

Following gene: 23099950

Centisome position: 70.44

GC content: 36.27

Gene sequence:

>2517_bases
ATGGCAGGCATTTTGACCAAAATATTTGGTGATGGTAACCAAAAACAATTAAAACGATTAGAAAAACAAGTAGATTTAAT
TGAACAGTTAGAACCTGAAATGGAGAAGCTAGAGGATATAGATTTTAAAAATAAAACGGAAGAGTTTAAGACACGTTATA
AAAATGGAGAATCTTTGAATGACCTATTAATAGAAGTTTATGCACTAGTTCGAGAAGCTTCTAAACGTGTACTTGGCATG
CGTCCTTTCCGTACACAGTTATTGGGTGCGATTGCCTTGCATGAAGGTAATATTTCTGAAATGAAAACAGGGGAAGGTAA
AACACTTGCTTCCACGATGCCCGCATACTTGAATGCATTAACAGATGAAGGTGTACACATTATCACTGTTAATGATTACT
TAGCAGAACGTGATGCGAAAGATAATGGGTTATTATTTGATTTTCTTGGTATAACAGTAGGTTTTAATCATAATGGCCTT
TCAAAAGATGAAAAACGTGAAGCTTATCTAGCAGACATTACCTACGGAACAAATAACGAATTTGGCTTTGATTATTTGCG
TGATAATATGGTCTTATACAAAGAGCAAATGGTACAGCGACCTTTAAATTTTGCAATTATTGATGAGGTAGACTCTATTC
TCATAGACGAAGCTCGTACACCATTAATTATTTCTGGTTCTGCGAAGAAATCTGCAGCGTTATATCAGCAGGCAGATGGA
TTTGTAAGAACGTTAAATAAAGAGAATGATTATACCTATGACGAGAAAACAAAAGGAGTTCAGCTAACAGAAGAAGGAAT
AAATAAGGCTGAAAACTACTTTTCGATTGAAAATCTATTTGATTTAGATCATGTTTCGTTGACGCACCATATAAATCAAG
CATTGAAAGCACATGTATCGATGCATCGTGATACGGATTATATGGTTGAAGAAGATGAAGTGGTTATTATTGATCAGTTC
ACAGGAAGAAAGATGAAAGGACGTCGTTATAGTGACGGACTTCATCAAGCCATAGAGGCAAAAGAAGGATTGCAAATTCA
AAATGAAAGTATGACGTTAGCATCTATTACTTTCCAGAACTATTTCCGAATGTATAATAAATTATCAGGAATGACTGGTA
CTGCCAAAACAGAAGAAGAAGAGTTTAGGAATATATATAATATGGATGTTATCGCAATTCCTACCAACTTACCTATTGCT
CGTGAGGATAGAGCAGATTTAATTTATAAGTCCATGGAAGGCAAGTTCCGTGCTGTTGTGGAAAATATTAAAGAACGGTA
TGAAAATGGACAACCAGTATTAGTAGGTACTGTTGCAGTAGAAACCTCTGAGTTAATCTCTAAATTGTTAAAACGTGCAG
GAGTTAAACATGAGGTTTTAAATGCGAAAAATCACTTTAGAGAAGCAGATATTATTGAACATGCCGGGCAAAGAGGATCA
GTGACAATTGCTACCAATATGGCTGGACGTGGGACAGATATTAAACTTGGTGATGGTGTTAAAGAACTTGGTGGTTTGGC
CGTCATCGGGACAGAACGTCATGAATCCCGAAGGATCGATAATCAGCTTCGAGGACGTTCTGGACGACAAGGAGATCCTG
GTATATCTCAATTTTTCCTTTCTATGGAAGATGAATTAATGCGTAGATTTGGCTCAGATAATTTAAAATCAATGATGGAG
CGTCTTGGAATGGACGATTCACAACCTATCGAGAGTAAAATGGTGTCAAGAGCAGTGGAATCAGCACAAAAACGCGTAGA
AGGAAATAACTTTGATGCTCGTAAAACAATTCTATCTTATGATGATGTATTGCGTGAACAGCGTGAGATTATTTATAAAC
AGCGATTTGAAGTTATTGACGATAATAGTGATCTAAGAGAGATCATTGAAAACATGATTCAATCGTCGATAGAGCGTGTA
GTTGCTACACATACACAAGACAGTGATGAAGAAAATTGGAACCTGGAAGCGATTATAGAATATTCCAATGGCAATTTATT
TGATCCAGATACTATTCATACAGATGATTTAAAAGATAAAGAAGCAAATGAAATTACAGAACTTCTTATGAAAAAAGTAA
AAGAGAAATATGATGCAAAAGAGCAGGAGCTAACACCAGAACAGTTCCGTGAATTTGAAAAAGTTATTCTGCTACGTACT
GTTGATTCAAAATGGATGGATCATATTGATCAGATGGATCAACTAAGACAGGGTATTCATTTAAGAGCTTATGGGCAAAA
TGATCCTTTACGTGAATATCAGATGGAAGGCTTCTCGATGTTTGAAGAAATGGTAGCAAACATTGAAGATGAAGTTGCTA
AGTACATCATGAAGGCACAAATCCGTGAAAACCTGCAACGACAAGAAGTGGTGAAAAATACACAAGCAGTTTCTGGCGGA
GAAGATAGCGGTAAGAAGAAAACAAAGAAACCGGTAGTGAAATCCAATACGGTAAAAAGGAATGATCCTTGTCCGTGCGG
AAGTGGTAAAAAGTATAAAAACTGCCACGGTCAATAA

Upstream 100 bases:

>100_bases
TCACCTACTGCTTAGTTGTCACATCAGTTTATAAAGTGTTATGATAAGAATGGTATCATATAGAAAATTCAATGATTGAA
ATTATTGAGGAGCGTTAGAT

Downstream 100 bases:

>100_bases
TAGTGAGTAACCAAAATGTAATTGTAAAGCCTCCGGTGTAATTGAATACATTAGGAGGCTATTCTGTGATTATTTTAAGG
AGAGATATAAGTGGAATTAA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 838; Mature: 837

Protein sequence:

>838_residues
MAGILTKIFGDGNQKQLKRLEKQVDLIEQLEPEMEKLEDIDFKNKTEEFKTRYKNGESLNDLLIEVYALVREASKRVLGM
RPFRTQLLGAIALHEGNISEMKTGEGKTLASTMPAYLNALTDEGVHIITVNDYLAERDAKDNGLLFDFLGITVGFNHNGL
SKDEKREAYLADITYGTNNEFGFDYLRDNMVLYKEQMVQRPLNFAIIDEVDSILIDEARTPLIISGSAKKSAALYQQADG
FVRTLNKENDYTYDEKTKGVQLTEEGINKAENYFSIENLFDLDHVSLTHHINQALKAHVSMHRDTDYMVEEDEVVIIDQF
TGRKMKGRRYSDGLHQAIEAKEGLQIQNESMTLASITFQNYFRMYNKLSGMTGTAKTEEEEFRNIYNMDVIAIPTNLPIA
REDRADLIYKSMEGKFRAVVENIKERYENGQPVLVGTVAVETSELISKLLKRAGVKHEVLNAKNHFREADIIEHAGQRGS
VTIATNMAGRGTDIKLGDGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGISQFFLSMEDELMRRFGSDNLKSMME
RLGMDDSQPIESKMVSRAVESAQKRVEGNNFDARKTILSYDDVLREQREIIYKQRFEVIDDNSDLREIIENMIQSSIERV
VATHTQDSDEENWNLEAIIEYSNGNLFDPDTIHTDDLKDKEANEITELLMKKVKEKYDAKEQELTPEQFREFEKVILLRT
VDSKWMDHIDQMDQLRQGIHLRAYGQNDPLREYQMEGFSMFEEMVANIEDEVAKYIMKAQIRENLQRQEVVKNTQAVSGG
EDSGKKKTKKPVVKSNTVKRNDPCPCGSGKKYKNCHGQ

Sequences:

>Translated_838_residues
MAGILTKIFGDGNQKQLKRLEKQVDLIEQLEPEMEKLEDIDFKNKTEEFKTRYKNGESLNDLLIEVYALVREASKRVLGM
RPFRTQLLGAIALHEGNISEMKTGEGKTLASTMPAYLNALTDEGVHIITVNDYLAERDAKDNGLLFDFLGITVGFNHNGL
SKDEKREAYLADITYGTNNEFGFDYLRDNMVLYKEQMVQRPLNFAIIDEVDSILIDEARTPLIISGSAKKSAALYQQADG
FVRTLNKENDYTYDEKTKGVQLTEEGINKAENYFSIENLFDLDHVSLTHHINQALKAHVSMHRDTDYMVEEDEVVIIDQF
TGRKMKGRRYSDGLHQAIEAKEGLQIQNESMTLASITFQNYFRMYNKLSGMTGTAKTEEEEFRNIYNMDVIAIPTNLPIA
REDRADLIYKSMEGKFRAVVENIKERYENGQPVLVGTVAVETSELISKLLKRAGVKHEVLNAKNHFREADIIEHAGQRGS
VTIATNMAGRGTDIKLGDGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGISQFFLSMEDELMRRFGSDNLKSMME
RLGMDDSQPIESKMVSRAVESAQKRVEGNNFDARKTILSYDDVLREQREIIYKQRFEVIDDNSDLREIIENMIQSSIERV
VATHTQDSDEENWNLEAIIEYSNGNLFDPDTIHTDDLKDKEANEITELLMKKVKEKYDAKEQELTPEQFREFEKVILLRT
VDSKWMDHIDQMDQLRQGIHLRAYGQNDPLREYQMEGFSMFEEMVANIEDEVAKYIMKAQIRENLQRQEVVKNTQAVSGG
EDSGKKKTKKPVVKSNTVKRNDPCPCGSGKKYKNCHGQ
>Mature_837_residues
AGILTKIFGDGNQKQLKRLEKQVDLIEQLEPEMEKLEDIDFKNKTEEFKTRYKNGESLNDLLIEVYALVREASKRVLGMR
PFRTQLLGAIALHEGNISEMKTGEGKTLASTMPAYLNALTDEGVHIITVNDYLAERDAKDNGLLFDFLGITVGFNHNGLS
KDEKREAYLADITYGTNNEFGFDYLRDNMVLYKEQMVQRPLNFAIIDEVDSILIDEARTPLIISGSAKKSAALYQQADGF
VRTLNKENDYTYDEKTKGVQLTEEGINKAENYFSIENLFDLDHVSLTHHINQALKAHVSMHRDTDYMVEEDEVVIIDQFT
GRKMKGRRYSDGLHQAIEAKEGLQIQNESMTLASITFQNYFRMYNKLSGMTGTAKTEEEEFRNIYNMDVIAIPTNLPIAR
EDRADLIYKSMEGKFRAVVENIKERYENGQPVLVGTVAVETSELISKLLKRAGVKHEVLNAKNHFREADIIEHAGQRGSV
TIATNMAGRGTDIKLGDGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGISQFFLSMEDELMRRFGSDNLKSMMER
LGMDDSQPIESKMVSRAVESAQKRVEGNNFDARKTILSYDDVLREQREIIYKQRFEVIDDNSDLREIIENMIQSSIERVV
ATHTQDSDEENWNLEAIIEYSNGNLFDPDTIHTDDLKDKEANEITELLMKKVKEKYDAKEQELTPEQFREFEKVILLRTV
DSKWMDHIDQMDQLRQGIHLRAYGQNDPLREYQMEGFSMFEEMVANIEDEVAKYIMKAQIRENLQRQEVVKNTQAVSGGE
DSGKKKTKKPVVKSNTVKRNDPCPCGSGKKYKNCHGQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=900, Percent_Identity=50, Blast_Score=851, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_OCEIH (Q8ENI7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693417.1
- HSSP:   P10408
- ProteinModelPortal:   Q8ENI7
- SMR:   Q8ENI7
- GeneID:   1017177
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2496
- NMPDR:   fig|221109.1.peg.2495
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   OIHE221109:OB2496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 95798; Mature: 95667

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGILTKIFGDGNQKQLKRLEKQVDLIEQLEPEMEKLEDIDFKNKTEEFKTRYKNGESLN
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCHHH
DLLIEVYALVREASKRVLGMRPFRTQLLGAIALHEGNISEMKTGEGKTLASTMPAYLNAL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHH
TDEGVHIITVNDYLAERDAKDNGLLFDFLGITVGFNHNGLSKDEKREAYLADITYGTNNE
CCCCEEEEEECHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCHHHCEEEEEEEECCCCC
FGFDYLRDNMVLYKEQMVQRPLNFAIIDEVDSILIDEARTPLIISGSAKKSAALYQQADG
CCHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCH
FVRTLNKENDYTYDEKTKGVQLTEEGINKAENYFSIENLFDLDHVSLTHHINQALKAHVS
HHHHHCCCCCCCCCCCCCCCEECHHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHHHHHHH
MHRDTDYMVEEDEVVIIDQFTGRKMKGRRYSDGLHQAIEAKEGLQIQNESMTLASITFQN
HCCCCCCEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEHHHHHHH
YFRMYNKLSGMTGTAKTEEEEFRNIYNMDVIAIPTNLPIAREDRADLIYKSMEGKFRAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHH
ENIKERYENGQPVLVGTVAVETSELISKLLKRAGVKHEVLNAKNHFREADIIEHAGQRGS
HHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VTIATNMAGRGTDIKLGDGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGISQFFL
EEEEECCCCCCCCEECCCCHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SMEDELMRRFGSDNLKSMMERLGMDDSQPIESKMVSRAVESAQKRVEGNNFDARKTILSY
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DDVLREQREIIYKQRFEVIDDNSDLREIIENMIQSSIERVVATHTQDSDEENWNLEAIIE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
YSNGNLFDPDTIHTDDLKDKEANEITELLMKKVKEKYDAKEQELTPEQFREFEKVILLRT
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH
VDSKWMDHIDQMDQLRQGIHLRAYGQNDPLREYQMEGFSMFEEMVANIEDEVAKYIMKAQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IRENLQRQEVVKNTQAVSGGEDSGKKKTKKPVVKSNTVKRNDPCPCGSGKKYKNCHGQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGILTKIFGDGNQKQLKRLEKQVDLIEQLEPEMEKLEDIDFKNKTEEFKTRYKNGESLN
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHCCCCHHH
DLLIEVYALVREASKRVLGMRPFRTQLLGAIALHEGNISEMKTGEGKTLASTMPAYLNAL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHH
TDEGVHIITVNDYLAERDAKDNGLLFDFLGITVGFNHNGLSKDEKREAYLADITYGTNNE
CCCCEEEEEECHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCHHHCEEEEEEEECCCCC
FGFDYLRDNMVLYKEQMVQRPLNFAIIDEVDSILIDEARTPLIISGSAKKSAALYQQADG
CCHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCH
FVRTLNKENDYTYDEKTKGVQLTEEGINKAENYFSIENLFDLDHVSLTHHINQALKAHVS
HHHHHCCCCCCCCCCCCCCCEECHHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHHHHHHH
MHRDTDYMVEEDEVVIIDQFTGRKMKGRRYSDGLHQAIEAKEGLQIQNESMTLASITFQN
HCCCCCCEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEHHHHHHH
YFRMYNKLSGMTGTAKTEEEEFRNIYNMDVIAIPTNLPIAREDRADLIYKSMEGKFRAVV
HHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHH
ENIKERYENGQPVLVGTVAVETSELISKLLKRAGVKHEVLNAKNHFREADIIEHAGQRGS
HHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VTIATNMAGRGTDIKLGDGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGISQFFL
EEEEECCCCCCCCEECCCCHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SMEDELMRRFGSDNLKSMMERLGMDDSQPIESKMVSRAVESAQKRVEGNNFDARKTILSY
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DDVLREQREIIYKQRFEVIDDNSDLREIIENMIQSSIERVVATHTQDSDEENWNLEAIIE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
YSNGNLFDPDTIHTDDLKDKEANEITELLMKKVKEKYDAKEQELTPEQFREFEKVILLRT
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH
VDSKWMDHIDQMDQLRQGIHLRAYGQNDPLREYQMEGFSMFEEMVANIEDEVAKYIMKAQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IRENLQRQEVVKNTQAVSGGEDSGKKKTKKPVVKSNTVKRNDPCPCGSGKKYKNCHGQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376