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The map label for this gene is ftsX [H]

Identifier: 23099947

GI number: 23099947

Start: 2551327

End: 2552220

Strand: Reverse

Name: ftsX [H]

Synonym: OB2492

Alternate gene names: 23099947

Gene position: 2552220-2551327 (Counterclockwise)

Preceding gene: 23099948

Following gene: 23099946

Centisome position: 70.3

GC content: 33.56

Gene sequence:

>894_bases
ATGAAGTTTAGAACGTTAATGAGACATATCCGTGAAGGAATAAAAAATATATTTAGAAATGGTTGGATGACGTTTGCGTC
AGTAGCTGCTGTTACAACAACTTTGATACTTGTAGCTGTATTTTTAGCACTAGTGTTAAATTTAGATCAAATGGCAACTA
ATATCGAAGAAGACGTTCAAATCAGTACGATAATAGACCGTACTGCAGATGAACAGCAGATTGTTGAGTTAGGGGAAGAA
TTAAAACAAATAGATGGTGTTGAAAAAGTACAATTTTCATCAAGAGATGATGAATTATCGAAGTTGATGGATAGTATGGG
AGAAGAAGGAGAAGCTTGGGGAATGTTCGAACAAGATAATCCATTACACCATACATATTATGTTGATCCAATGACACCTG
AACAAACGGAGCAAATTGCTTCACAAATTGAATCTTTAAATTATGTAGATGAGGTTCTATATGGACAAGATGTAGTACAA
AAATTGTTCGAGTTTAATAGTTATGCAAGGACAATTGGATTAGGTTTGATTGTAGCTCTTGTATTTACTGCTATATTCCT
AATCTCAAATACTATCAAAATCACAATTATTGCACGTAGTACAGAAATAGGCATTCAAAAACTAGTGGGCGCTAAAAATA
GTTTTATTCGTTGGCCATTTTTTATTGAAGGAGCTTTGCTCGGTATTCTCGGATCAATCATACCGATTACTGTAATATTG
AGTGGTTATTACTATATATACACTAATTTTAATGACTCTATAACAATTCCATTTGTGGAATTATTACCATTTAATCCATT
TGCTTGGCAATTAGCTGGAATGGTACTTCTAATTGGTGCTGTAATTGGTGTATGGGGAAGCGTAATGAGTGTACGTAAGT
TCTTAAAAGTCTGA

Upstream 100 bases:

>100_bases
GCCACACATAGTAAAGAAATCGTAGACAGGAAGAAGAAACGTGTAATTGCGTTTGAAGATGGAGTCATCGCGAGAGACGA
ACAACGAGGTGAATACGGCT

Downstream 100 bases:

>100_bases
TAGATGATGACGAATTCCAAGCAGAGGGGGAAATACGATTGAAAAAGATAACTTCCATTCTAGTTATTACTTTATTAACA
TTCACTGTATTTGGACAAAA

Product: cell-division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKFRTLMRHIREGIKNIFRNGWMTFASVAAVTTTLILVAVFLALVLNLDQMATNIEEDVQISTIIDRTADEQQIVELGEE
LKQIDGVEKVQFSSRDDELSKLMDSMGEEGEAWGMFEQDNPLHHTYYVDPMTPEQTEQIASQIESLNYVDEVLYGQDVVQ
KLFEFNSYARTIGLGLIVALVFTAIFLISNTIKITIIARSTEIGIQKLVGAKNSFIRWPFFIEGALLGILGSIIPITVIL
SGYYYIYTNFNDSITIPFVELLPFNPFAWQLAGMVLLIGAVIGVWGSVMSVRKFLKV

Sequences:

>Translated_297_residues
MKFRTLMRHIREGIKNIFRNGWMTFASVAAVTTTLILVAVFLALVLNLDQMATNIEEDVQISTIIDRTADEQQIVELGEE
LKQIDGVEKVQFSSRDDELSKLMDSMGEEGEAWGMFEQDNPLHHTYYVDPMTPEQTEQIASQIESLNYVDEVLYGQDVVQ
KLFEFNSYARTIGLGLIVALVFTAIFLISNTIKITIIARSTEIGIQKLVGAKNSFIRWPFFIEGALLGILGSIIPITVIL
SGYYYIYTNFNDSITIPFVELLPFNPFAWQLAGMVLLIGAVIGVWGSVMSVRKFLKV
>Mature_297_residues
MKFRTLMRHIREGIKNIFRNGWMTFASVAAVTTTLILVAVFLALVLNLDQMATNIEEDVQISTIIDRTADEQQIVELGEE
LKQIDGVEKVQFSSRDDELSKLMDSMGEEGEAWGMFEQDNPLHHTYYVDPMTPEQTEQIASQIESLNYVDEVLYGQDVVQ
KLFEFNSYARTIGLGLIVALVFTAIFLISNTIKITIIARSTEIGIQKLVGAKNSFIRWPFFIEGALLGILGSIIPITVIL
SGYYYIYTNFNDSITIPFVELLPFNPFAWQLAGMVLLIGAVIGVWGSVMSVRKFLKV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=236, Percent_Identity=29.6610169491525, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33452; Mature: 33452

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRTLMRHIREGIKNIFRNGWMTFASVAAVTTTLILVAVFLALVLNLDQMATNIEEDVQ
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
ISTIIDRTADEQQIVELGEELKQIDGVEKVQFSSRDDELSKLMDSMGEEGEAWGMFEQDN
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PLHHTYYVDPMTPEQTEQIASQIESLNYVDEVLYGQDVVQKLFEFNSYARTIGLGLIVAL
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFTAIFLISNTIKITIIARSTEIGIQKLVGAKNSFIRWPFFIEGALLGILGSIIPITVIL
HHHHHHHHCCCEEEEEEEECHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHH
SGYYYIYTNFNDSITIPFVELLPFNPFAWQLAGMVLLIGAVIGVWGSVMSVRKFLKV
CCEEEEEECCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFRTLMRHIREGIKNIFRNGWMTFASVAAVTTTLILVAVFLALVLNLDQMATNIEEDVQ
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
ISTIIDRTADEQQIVELGEELKQIDGVEKVQFSSRDDELSKLMDSMGEEGEAWGMFEQDN
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PLHHTYYVDPMTPEQTEQIASQIESLNYVDEVLYGQDVVQKLFEFNSYARTIGLGLIVAL
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFTAIFLISNTIKITIIARSTEIGIQKLVGAKNSFIRWPFFIEGALLGILGSIIPITVIL
HHHHHHHHCCCEEEEEEEECHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHH
SGYYYIYTNFNDSITIPFVELLPFNPFAWQLAGMVLLIGAVIGVWGSVMSVRKFLKV
CCEEEEEECCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]