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The map label for this gene is appC [H]

Identifier: 23099715

GI number: 23099715

Start: 2301722

End: 2302636

Strand: Reverse

Name: appC [H]

Synonym: OB2260

Alternate gene names: 23099715

Gene position: 2302636-2301722 (Counterclockwise)

Preceding gene: 23099716

Following gene: 23099714

Centisome position: 63.42

GC content: 35.41

Gene sequence:

>915_bases
ATGCCACAGGAACCAGTACCTAATACTCCTAAAGAAGGTGTCATAGTCAAGAAAGAAAAAAGTAAAAGCCCCTTTCAAAT
AGGAGTTAGTAGATTTCTAAAAAATAAATTAGCAGTAGTTAGTCTTATCATTTTGGTATTAATTATTTTAATCTGTATAT
TTGCACCATTATTTACTGATCTTGATCCTGAGAAAACAGATCTTTTAAAGATAGAGAAAGGTCCAAGTGAAGAGCATATA
TTAGGAACCAATGGAGTTGGACAAGATAATTTTTCTCGACTGTTATATGGAGGAAGAATTTCTTTGATCGTTGGTTTTAG
CGCAATGTTCTTTACTTTAGCAATCGGTGTTGTTTTGGGGTCACTTGCTGGATATTATGGCGGTAAAGTAGACAGTATTA
TCATGCGTGGAGCAGATATTATGTTAATGTTGCCATTTTTAGTATTAGTACTTACCATTATGGCGGTAATTGATAATGTA
ACCATTGGGTTATTTGTTACAACAATCGCATTAACGTCATGGCCAAATCTAACAAGAATTATCCGGGGGTCATATTTATC
CTTGCGTGAACAAGAATTTGTGCTAAGTGCACATGCCATTGGTGCGAATGATTTTCGGATTATTTTTAAGCACTTTATTC
CTAATGCAATTGGTCCAATTGTTGTAAATGCCACGCTTATGATGGCTTCTTATATTATCATAGAATCCGGTCTTAGTTTT
ATAGGATTTGGAATTCCACAACCAACACCAACTTGGGGGAATATGATATCTGAAGCGCAAAATATTCGGATTTTACGTGA
CCATCCAGAAGCTTGGATACCGCCAGGATTGGCTATTTTTATTACTGTACTAGCCATAAATTTTATTGGAGACGGTCTAC
GAGATGCATTTGATCCAAAAAGTAACCAACGATAA

Upstream 100 bases:

>100_bases
TAGGTGTTTTAGTCTTAGTTGGAAACTTAGTTGCTGACATTATGTATAGTGTTATTGATCCTAGAATTCGTTATGATTGA
GGTGAGTGAAAATGCAATCA

Downstream 100 bases:

>100_bases
ATATACCGCAAGAAGTCAGCATCAAGTACGTTGATTTCTTGCGGTATTATTTTGCATTACATAAATGATTTACTTTCTTT
ATGTAATGCGTAACAATAGG

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPQEPVPNTPKEGVIVKKEKSKSPFQIGVSRFLKNKLAVVSLIILVLIILICIFAPLFTDLDPEKTDLLKIEKGPSEEHI
LGTNGVGQDNFSRLLYGGRISLIVGFSAMFFTLAIGVVLGSLAGYYGGKVDSIIMRGADIMLMLPFLVLVLTIMAVIDNV
TIGLFVTTIALTSWPNLTRIIRGSYLSLREQEFVLSAHAIGANDFRIIFKHFIPNAIGPIVVNATLMMASYIIIESGLSF
IGFGIPQPTPTWGNMISEAQNIRILRDHPEAWIPPGLAIFITVLAINFIGDGLRDAFDPKSNQR

Sequences:

>Translated_304_residues
MPQEPVPNTPKEGVIVKKEKSKSPFQIGVSRFLKNKLAVVSLIILVLIILICIFAPLFTDLDPEKTDLLKIEKGPSEEHI
LGTNGVGQDNFSRLLYGGRISLIVGFSAMFFTLAIGVVLGSLAGYYGGKVDSIIMRGADIMLMLPFLVLVLTIMAVIDNV
TIGLFVTTIALTSWPNLTRIIRGSYLSLREQEFVLSAHAIGANDFRIIFKHFIPNAIGPIVVNATLMMASYIIIESGLSF
IGFGIPQPTPTWGNMISEAQNIRILRDHPEAWIPPGLAIFITVLAINFIGDGLRDAFDPKSNQR
>Mature_303_residues
PQEPVPNTPKEGVIVKKEKSKSPFQIGVSRFLKNKLAVVSLIILVLIILICIFAPLFTDLDPEKTDLLKIEKGPSEEHIL
GTNGVGQDNFSRLLYGGRISLIVGFSAMFFTLAIGVVLGSLAGYYGGKVDSIIMRGADIMLMLPFLVLVLTIMAVIDNVT
IGLFVTTIALTSWPNLTRIIRGSYLSLREQEFVLSAHAIGANDFRIIFKHFIPNAIGPIVVNATLMMASYIIIESGLSFI
GFGIPQPTPTWGNMISEAQNIRILRDHPEAWIPPGLAIFITVLAINFIGDGLRDAFDPKSNQR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=38.6759581881533, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787498, Length=285, Percent_Identity=38.5964912280702, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=36.5671641791045, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1789964, Length=301, Percent_Identity=38.5382059800665, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789889, Length=239, Percent_Identity=35.9832635983264, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=32.7433628318584, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787549, Length=289, Percent_Identity=26.2975778546713, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33292; Mature: 33161

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQEPVPNTPKEGVIVKKEKSKSPFQIGVSRFLKNKLAVVSLIILVLIILICIFAPLFTD
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDPEKTDLLKIEKGPSEEHILGTNGVGQDNFSRLLYGGRISLIVGFSAMFFTLAIGVVLG
CCCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLAGYYGGKVDSIIMRGADIMLMLPFLVLVLTIMAVIDNVTIGLFVTTIALTSWPNLTRI
HHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
IRGSYLSLREQEFVLSAHAIGANDFRIIFKHFIPNAIGPIVVNATLMMASYIIIESGLSF
HHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHH
IGFGIPQPTPTWGNMISEAQNIRILRDHPEAWIPPGLAIFITVLAINFIGDGLRDAFDPK
EECCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SNQR
CCCC
>Mature Secondary Structure 
PQEPVPNTPKEGVIVKKEKSKSPFQIGVSRFLKNKLAVVSLIILVLIILICIFAPLFTD
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDPEKTDLLKIEKGPSEEHILGTNGVGQDNFSRLLYGGRISLIVGFSAMFFTLAIGVVLG
CCCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLAGYYGGKVDSIIMRGADIMLMLPFLVLVLTIMAVIDNVTIGLFVTTIALTSWPNLTRI
HHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
IRGSYLSLREQEFVLSAHAIGANDFRIIFKHFIPNAIGPIVVNATLMMASYIIIESGLSF
HHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHH
IGFGIPQPTPTWGNMISEAQNIRILRDHPEAWIPPGLAIFITVLAINFIGDGLRDAFDPK
EECCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SNQR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]