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The map label for this gene is nrdR

Identifier: 23099613

GI number: 23099613

Start: 2191013

End: 2191486

Strand: Reverse

Name: nrdR

Synonym: OB2158

Alternate gene names: 23099613

Gene position: 2191486-2191013 (Counterclockwise)

Preceding gene: 23099614

Following gene: 23099612

Centisome position: 60.36

GC content: 35.44

Gene sequence:

>474_bases
ATGCGATGTTCCAATTGTCAAAATAAGAATACTAAAGTGTTAGACTCTCGACCGATAGAAGAAGGAAGAGCAATCAGACG
ACGTAGGGAATGTGAACGGTGTGGATTCCGGTTTACTACTTTTGAACGAATTGAAGAAGTTCCTTTAATTGTGGTAAAGA
AAGATGGTGTTCGTCAAGAGTTTTCGCGAGAAAAGCTAATGCGCGGTCTTATACGGGCATGTGAAAAAAGACCAGTTGCT
TTAGAAACCATAGAAAGTATAGCGCTAGAAGTAGAAAAAAAATTACGAAATGCAGGTAATCCAGAAGTTTCAAGTAATTC
TATCGGTGAAATGGTAATGGAACTTTTATCGAAAGTAGATGAAGTTTCGTATGTTCGCTTTGCATCTGTATATCGCCAAT
TTAAAGATATAACTGTGTTCTTAGATGAATTAAAAGATATAATTAATACGGATAAATCGATGAAAGATAAATGA

Upstream 100 bases:

>100_bases
GATTTTGGACATAGTTCTAAAGTTATTCAAGAATTATATGAACATATAAATAAAGAACTTCAGCTAATTTCGGAACATTA
GAGAATGGGGTTGAACAATG

Downstream 100 bases:

>100_bases
AAGAGTAGAAAGGGTGTGTGATTTATATGAATTTTATTGGGAAGATTCTACCTATTGATGGGTACTATGTAATGAAAAAA
GAACATTTACCTGTGGATTA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQEFSREKLMRGLIRACEKRPVA
LETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVDEVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK

Sequences:

>Translated_157_residues
MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQEFSREKLMRGLIRACEKRPVA
LETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVDEVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK
>Mature_157_residues
MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQEFSREKLMRGLIRACEKRPVA
LETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVDEVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=49.3055555555556, Blast_Score=132, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_OCEIH (Q8EPF0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693079.1
- GeneID:   1015609
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2158
- NMPDR:   fig|221109.1.peg.2156
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   OIHE221109:OB2158-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18308; Mature: 18308

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCHHHH
FSREKLMRGLIRACEKRPVALETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRCSNCQNKNTKVLDSRPIEEGRAIRRRRECERCGFRFTTFERIEEVPLIVVKKDGVRQE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCHHHH
FSREKLMRGLIRACEKRPVALETIESIALEVEKKLRNAGNPEVSSNSIGEMVMELLSKVD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EVSYVRFASVYRQFKDITVFLDELKDIINTDKSMKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376