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The map label for this gene is cymR [H]

Identifier: 23099471

GI number: 23099471

Start: 2041052

End: 2041471

Strand: Reverse

Name: cymR [H]

Synonym: OB2016

Alternate gene names: 23099471

Gene position: 2041471-2041052 (Counterclockwise)

Preceding gene: 23099474

Following gene: 23099470

Centisome position: 56.23

GC content: 35.0

Gene sequence:

>420_bases
ATGAAAATTTCAACAAAAGGAAGATACGGATTAACAATTATGATTGAGTTAGCACTAAACTATGGACAGGGACCAACTTC
TTTGAAAATGATTGCCAAAGAAAATAATCTTTCCGAGCATTACTTGGAGCAGTTAGCATCTCCTTTGAGAAATGCAGGTT
TAGTGAAGAGTGTACGTGGTGCATATGGTGGATATATGTTATCAAGAGAACCAAAATCGATTACAGCGAGTGATGTATTG
AGAGTTCTTGAGGGTCCTTTAACAATTGTAGAAGGCATGGAAGAAGAAAAACCTGCTCAACAATCCTTATGGTTAAGTAT
ACGTGACGCAGTTAAAGATGTTTTAGATCAGACAACATTACAAGATTTAGTAGATCATGAAAATGATGAACCACGTGATG
CTTATATGTTTTATATTTAA

Upstream 100 bases:

>100_bases
TCAAGCTTATAGTGGATTCTAGTGAAATGCAAGAGGATGGTTGTCATGATATAATAACATGTAGAATGTAATAGGAACGA
AGAATATGAGGTGTCTATAA

Downstream 100 bases:

>100_bases
TTTGCATAGTCAGTTTCATTAAGCTAAGTCTTAGTAAAAAATATTCATACTTTATATCAAGTTTTTAAAGTATGAAATTG
ATACAGTTAGATAGAGAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKISTKGRYGLTIMIELALNYGQGPTSLKMIAKENNLSEHYLEQLASPLRNAGLVKSVRGAYGGYMLSREPKSITASDVL
RVLEGPLTIVEGMEEEKPAQQSLWLSIRDAVKDVLDQTTLQDLVDHENDEPRDAYMFYI

Sequences:

>Translated_139_residues
MKISTKGRYGLTIMIELALNYGQGPTSLKMIAKENNLSEHYLEQLASPLRNAGLVKSVRGAYGGYMLSREPKSITASDVL
RVLEGPLTIVEGMEEEKPAQQSLWLSIRDAVKDVLDQTTLQDLVDHENDEPRDAYMFYI
>Mature_139_residues
MKISTKGRYGLTIMIELALNYGQGPTSLKMIAKENNLSEHYLEQLASPLRNAGLVKSVRGAYGGYMLSREPKSITASDVL
RVLEGPLTIVEGMEEEKPAQQSLWLSIRDAVKDVLDQTTLQDLVDHENDEPRDAYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=149, Percent_Identity=32.8859060402685, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15590; Mature: 15590

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMIELALNYGQGPTSLKMIAKENNLSEHYLEQLASPLRNAGLVKSVRG
CCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHH
AYGGYMLSREPKSITASDVLRVLEGPLTIVEGMEEEKPAQQSLWLSIRDAVKDVLDQTTL
HHCCEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QDLVDHENDEPRDAYMFYI
HHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMIELALNYGQGPTSLKMIAKENNLSEHYLEQLASPLRNAGLVKSVRG
CCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHH
AYGGYMLSREPKSITASDVLRVLEGPLTIVEGMEEEKPAQQSLWLSIRDAVKDVLDQTTL
HHCCEEECCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QDLVDHENDEPRDAYMFYI
HHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]