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The map label for this gene is pgsA [H]

Identifier: 23099077

GI number: 23099077

Start: 1661302

End: 1661880

Strand: Direct

Name: pgsA [H]

Synonym: OB1622

Alternate gene names: 23099077

Gene position: 1661302-1661880 (Clockwise)

Preceding gene: 23099076

Following gene: 23099078

Centisome position: 45.76

GC content: 33.16

Gene sequence:

>579_bases
ATGAATTTACCAAATAAGTTAACATTTTCCAGAATATTAATGATCCCGATTTTTATTTTATTATTATCCATTCCTTTTCC
TTGGGGAGCTTGGGATATCGGTAATAGTGAATTACCAGTCGCTCATTTTCTAGCCGCATTGATCTTTATTATTGCAGCTG
CTACTGATTGGGTTGATGGTTATTATGCTAGAAAGTATCAATTAGTTACAAATTTAGGAAAGTTTATGGACCCGCTTGCA
GATAAGTTACTAGTATCTGCTGCATTAATACTATTAGTGGAAATGGAAATTGCCCCAGCTTGGATAGTCATCATTATTAT
AAGCAGAGAATTAGCTGTTACAGGTTTAAGACTAGTAGCTGCAGGAGAAGGAATCGTACTTGCAGCAGGAAGTATGGGCA
AATTAAAAACTGCAACTCAAATGATTTCTATTGCGGTATTATTACTACATAATTTTCCGTTTTCCTATATTGATTTTCCA
TTCGGTATAATCATGCTATATATAGCATTAATTTTCACAATTATTTCTGGAGTGGATTATTTTATTAAAAACTGGCATGT
GATGAGGGATTCAAAATAA

Upstream 100 bases:

>100_bases
CTGCACATCAAAAAATAGAAATCCAATTTAATTAAACTTTGACCCTCCTATTTTTTGTGGGAGGGTTATATTTATTACTC
AAAAGACGGAGGCAGACAGA

Downstream 100 bases:

>100_bases
TGAAAAATTATCAAGCTGAAATAGTAGCGGTTGGTACGGAATTGTTATTAGGCCAAATTGCGAATACAAATGCACAATGG
TTATCCGAAAAATTAGCAAC

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNLPNKLTFSRILMIPIFILLLSIPFPWGAWDIGNSELPVAHFLAALIFIIAAATDWVDGYYARKYQLVTNLGKFMDPLA
DKLLVSAALILLVEMEIAPAWIVIIIISRELAVTGLRLVAAGEGIVLAAGSMGKLKTATQMISIAVLLLHNFPFSYIDFP
FGIIMLYIALIFTIISGVDYFIKNWHVMRDSK

Sequences:

>Translated_192_residues
MNLPNKLTFSRILMIPIFILLLSIPFPWGAWDIGNSELPVAHFLAALIFIIAAATDWVDGYYARKYQLVTNLGKFMDPLA
DKLLVSAALILLVEMEIAPAWIVIIIISRELAVTGLRLVAAGEGIVLAAGSMGKLKTATQMISIAVLLLHNFPFSYIDFP
FGIIMLYIALIFTIISGVDYFIKNWHVMRDSK
>Mature_192_residues
MNLPNKLTFSRILMIPIFILLLSIPFPWGAWDIGNSELPVAHFLAALIFIIAAATDWVDGYYARKYQLVTNLGKFMDPLA
DKLLVSAALILLVEMEIAPAWIVIIIISRELAVTGLRLVAAGEGIVLAAGSMGKLKTATQMISIAVLLLHNFPFSYIDFP
FGIIMLYIALIFTIISGVDYFIKNWHVMRDSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=34.2391304347826, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21342; Mature: 21342

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTFSRILMIPIFILLLSIPFPWGAWDIGNSELPVAHFLAALIFIIAAATDWVDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YYARKYQLVTNLGKFMDPLADKLLVSAALILLVEMEIAPAWIVIIIISRELAVTGLRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHEE
AGEGIVLAAGSMGKLKTATQMISIAVLLLHNFPFSYIDFPFGIIMLYIALIFTIISGVDY
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FIKNWHVMRDSK
HHHCCCEECCCC
>Mature Secondary Structure
MNLPNKLTFSRILMIPIFILLLSIPFPWGAWDIGNSELPVAHFLAALIFIIAAATDWVDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YYARKYQLVTNLGKFMDPLADKLLVSAALILLVEMEIAPAWIVIIIISRELAVTGLRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHEE
AGEGIVLAAGSMGKLKTATQMISIAVLLLHNFPFSYIDFPFGIIMLYIALIFTIISGVDY
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FIKNWHVMRDSK
HHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]