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The map label for this gene is rsmH [H]

Identifier: 23098917

GI number: 23098917

Start: 1499028

End: 1500017

Strand: Direct

Name: rsmH [H]

Synonym: OB1462

Alternate gene names: 23098917

Gene position: 1499028-1500017 (Clockwise)

Preceding gene: 23098916

Following gene: 23098918

Centisome position: 41.29

GC content: 37.58

Gene sequence:

>990_bases
GTGGGTGTTGAAATGTTTGAGCATTATAGTGTATTAAAAGAAGAATCAATTAAAGGATTAGCAATTAAGCCAGATGGAAT
TTATGTTGATTGTACAACTGGTGGTGGGGGACATTCTCTGGAAATAGCTTCTAGACTAAATGAGAATGGTCAGCTATTCG
CATTTGATCAAGATAAGGATGCTTTAGCTGCTGCGAGAGATAGATTATCTACATATGCAGATAGAATTGTATTTGTGCAA
TCGAACTTTCGTGGTTTAGAAGAACAGTTGAAAAAGCATGGAATTGAACAAGTAGATGGTATTTTATTTGATTTAGGTGT
TTCCTCTCCTCAATTGGACAGAGGGGATAGAGGTTTCAGTTATAATCATGACGCTTTGTTAGATATGCGAATGGATCAAT
CGCAGCATCTTTCAGCTTATGAAGTTGTCAACGAATGGTCATACGAACGTTTGGTTTCTATTTTCTTTTCATATGGGGAA
GAGAAGTTTTCTAAACAAATCGCCAGAAAAATAGAAGCTTATCGTGAACAACAGGATATTAAAACGACACATCAATTAGT
AGAGATAATTAAAGATGCAATACCAGCACCAGCTCGGAGAAAAGGGGGGCATCCTGCCAAGCGTATCTTTCAAGCGTTGC
GTATTGCTGTAAATGATGAATTGGAGGTATTTAATAATGCCTTGCATCAAGCAGCTAGGCTTATAGCAGTGAATGGCAGG
ATAGCAGTAATAACTTTCCACTCTTTAGAAGATCGGATATGTAAGCAAGCTTTTAAAAAATGGAGTACAGATAAACCTAC
ACCTAGGCATTTACCGATAGTTCCTGAGTCGCATCAAGCTCCATTTAAATTGGTGACAAGGAAACCTATTACAGCAGATA
CTTCCGAATTAGATGAAAACCGTAGATCGCGTTCTGCGAAGTTAAGAGTTATCGAAAAAGTAAGTGAATGGGATCATGAA
TTTACGTATGAAGAAGGGTGGAGAAAATAA

Upstream 100 bases:

>100_bases
AAGATTATGTAACGGAGTCTGAAGATTCATTTGCAGAAATAGCGGAAAACTTAATGGACTTTGATATTTAAAATTTCCAG
TACAAGATAGAAGAATTAAA

Downstream 100 bases:

>100_bases
TGAGTGTAAATCATGCAACGAAATGGGAAACAAATACGCAGTATCGTCCGGAAACACAACCGCAAACCGTTGTTAAAAAA
GTAAAGCGAACTAGATGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGVEMFEHYSVLKEESIKGLAIKPDGIYVDCTTGGGGHSLEIASRLNENGQLFAFDQDKDALAAARDRLSTYADRIVFVQ
SNFRGLEEQLKKHGIEQVDGILFDLGVSSPQLDRGDRGFSYNHDALLDMRMDQSQHLSAYEVVNEWSYERLVSIFFSYGE
EKFSKQIARKIEAYREQQDIKTTHQLVEIIKDAIPAPARRKGGHPAKRIFQALRIAVNDELEVFNNALHQAARLIAVNGR
IAVITFHSLEDRICKQAFKKWSTDKPTPRHLPIVPESHQAPFKLVTRKPITADTSELDENRRSRSAKLRVIEKVSEWDHE
FTYEEGWRK

Sequences:

>Translated_329_residues
MGVEMFEHYSVLKEESIKGLAIKPDGIYVDCTTGGGGHSLEIASRLNENGQLFAFDQDKDALAAARDRLSTYADRIVFVQ
SNFRGLEEQLKKHGIEQVDGILFDLGVSSPQLDRGDRGFSYNHDALLDMRMDQSQHLSAYEVVNEWSYERLVSIFFSYGE
EKFSKQIARKIEAYREQQDIKTTHQLVEIIKDAIPAPARRKGGHPAKRIFQALRIAVNDELEVFNNALHQAARLIAVNGR
IAVITFHSLEDRICKQAFKKWSTDKPTPRHLPIVPESHQAPFKLVTRKPITADTSELDENRRSRSAKLRVIEKVSEWDHE
FTYEEGWRK
>Mature_328_residues
GVEMFEHYSVLKEESIKGLAIKPDGIYVDCTTGGGGHSLEIASRLNENGQLFAFDQDKDALAAARDRLSTYADRIVFVQS
NFRGLEEQLKKHGIEQVDGILFDLGVSSPQLDRGDRGFSYNHDALLDMRMDQSQHLSAYEVVNEWSYERLVSIFFSYGEE
KFSKQIARKIEAYREQQDIKTTHQLVEIIKDAIPAPARRKGGHPAKRIFQALRIAVNDELEVFNNALHQAARLIAVNGRI
AVITFHSLEDRICKQAFKKWSTDKPTPRHLPIVPESHQAPFKLVTRKPITADTSELDENRRSRSAKLRVIEKVSEWDHEF
TYEEGWRK

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=344, Percent_Identity=33.4302325581395, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI165377202, Length=190, Percent_Identity=36.8421052631579, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786270, Length=320, Percent_Identity=40.625, Blast_Score=218, Evalue=4e-58,
Organism=Drosophila melanogaster, GI62472493, Length=337, Percent_Identity=36.2017804154303, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28571637, Length=337, Percent_Identity=36.2017804154303, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 37655; Mature: 37524

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEMFEHYSVLKEESIKGLAIKPDGIYVDCTTGGGGHSLEIASRLNENGQLFAFDQDKD
CCCHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCHHHHHHCCCCCCEEEECCCHH
ALAAARDRLSTYADRIVFVQSNFRGLEEQLKKHGIEQVDGILFDLGVSSPQLDRGDRGFS
HHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCCCCCCCC
YNHDALLDMRMDQSQHLSAYEVVNEWSYERLVSIFFSYGEEKFSKQIARKIEAYREQQDI
CCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KTTHQLVEIIKDAIPAPARRKGGHPAKRIFQALRIAVNDELEVFNNALHQAARLIAVNGR
HHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCE
IAVITFHSLEDRICKQAFKKWSTDKPTPRHLPIVPESHQAPFKLVTRKPITADTSELDEN
EEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHH
RRSRSAKLRVIEKVSEWDHEFTYEEGWRK
HHHHHHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure 
GVEMFEHYSVLKEESIKGLAIKPDGIYVDCTTGGGGHSLEIASRLNENGQLFAFDQDKD
CCHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCHHHHHHCCCCCCEEEECCCHH
ALAAARDRLSTYADRIVFVQSNFRGLEEQLKKHGIEQVDGILFDLGVSSPQLDRGDRGFS
HHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCCCCCCCC
YNHDALLDMRMDQSQHLSAYEVVNEWSYERLVSIFFSYGEEKFSKQIARKIEAYREQQDI
CCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
KTTHQLVEIIKDAIPAPARRKGGHPAKRIFQALRIAVNDELEVFNNALHQAARLIAVNGR
HHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCE
IAVITFHSLEDRICKQAFKKWSTDKPTPRHLPIVPESHQAPFKLVTRKPITADTSELDEN
EEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHH
RRSRSAKLRVIEKVSEWDHEFTYEEGWRK
HHHHHHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]