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The map label for this gene is ubiB [C]

Identifier: 23098764

GI number: 23098764

Start: 1353928

End: 1355583

Strand: Direct

Name: ubiB [C]

Synonym: OB1309

Alternate gene names: 23098764

Gene position: 1353928-1355583 (Clockwise)

Preceding gene: 23098762

Following gene: 23098766

Centisome position: 37.29

GC content: 33.21

Gene sequence:

>1656_bases
ATGCAAAGATATAGAGAAATTGTTGTCGCCTTTTCTAGAAATGGGTTCGGATATATTGTAAAAGAGTTAGGATTGCATAA
AATTTCCTCCCTACCAAAGCGATTGTTTGAGCAAGGAGATAGAGAAGTACATAATAAAACAACTGGTGAAAGAATTCGGT
TATTTTTAGAGGAATTAGGACCTACATTTATCAAACTTGGACAAATAGCAAGTACAAGACAGGATTTAATACCAAAAGAT
ATTATTGAAGAATTAGAAAAACTACAGGATCAAGTTGCACCGTTTTCTTTTTCTGATGTAAAAGAAATAATAGACAAGGA
ATTACAAGAACCTATAGATGTTGTTTTCGAATCCTTTGATGAAGATCCAATTGCAGCAGCTTCTATCGGTCAAGTTCATT
ATGGAGTTCTTCGGACAGGACAAGAAGTAGCTGTAAAAATACAACGACCAAATTTAGAAGAAAAAGTACATACTGATTTA
GAAATATTAATGAATATAGCAAAGCTAGCCGAGTCAAGGCTTGATTGGGCAAAAAAGTATCAGTTATGCGCTATTATAAA
AGAATTTTCCAATTCATTAACTGCTGAATTAGACTATACGTTAGAAGGAAGAAATGCACATCGGATTGCACAACAATTTA
AAAAACATGATGATGTAGTCGTGCCAAATGTTTATTGGGATCTTACAACAGAAAAAGTTCTAACGATGGAGTATATAAAA
GGGATTAAATTAGATGAGAATACGAAGCTTGTTCGTGAAGGGTATAATCCAAAATTAATTGCAGAAAAATTAATTCAAAA
ACAATTTCAGCAAATCTTAATAGATGGTTTTTTTCATGCAGATCCGCATCCCGGTAATGTAATGGTCTTACCTAATCATA
AAATTCTTTTTATGGACTTTGGTATGGTTGGGAGATTAACCGCTACAATGAAAGACCATTTATCCTCGCTCATCGTAGCT
ATCATGAGACAAAATACAAAATCAATAATTAAAGCAATTTATAGAATGGGAATCGTATCAGAGGGTGTTGATGCGGACTA
TATGTATGCAGATATTGATGATTTGAGAGACAAGTACTATGATATTCCATTCAGCCAAGTGAGTATTGGAGAAGCAATTA
ATGATTTATTCCGAGTAGCAACCACTCATGGAATAAGAATTCCAACTGACTTATCTTTAGTCGGAAAATCATTATTAACG
CTTGAAGGTACTGTAGAAAGATTAGATCCTGATATTAGCATTGTAAAAATTGCAGAGCCTTTCGGGAAAAGATTATTAAG
AGAAAAATATCAGCCCAAAAAAGTTGCTGATGAAGTATACCAACAAGCGGAAGATTACAAAGATTTAATATTGGACTTTC
CTGATCATATTAATCATTTATACAAGGTTATTCGAAGAGGAAAATTACCTTTAGAAATATCTGTTTCTCGAGTAGAAGCT
TTTTTGAAAAAACTCGATCGAATCAGTAATCGCCTTTCATTTAGTATTGTATTGCTTGCATTCAGTATTATTATGGTAGG
ATTAATTATTGGATCTGCTCTAGCAGGAGAATCTTCTTATTTGTGGAGCTTGCCAGTAATTGAAATTGGTTTTGTCGTTG
CGATAGGTATGTTCCTATGGCTACTTTATTCTATCTTTCGTTCAGGAAGGTTTTAA

Upstream 100 bases:

>100_bases
GAAAGATTTGTTATGAAATAGTAATAATGGGGTATAGAATAAGAATGAATAAATTGTTAGCTAGGGAGGGTTTGCTATTT
TTAAAAGAAGAATACGTCAT

Downstream 100 bases:

>100_bases
GTGCATGAATAATAAAAATCGCAGTCATCATTGGTTGATGACTGCGATTTTTATTTGTTCTGTTCTGTAATCATTAAAAT
ACTTTATCTCCATTAAAGAT

Product: ABC transporter

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MQRYREIVVAFSRNGFGYIVKELGLHKISSLPKRLFEQGDREVHNKTTGERIRLFLEELGPTFIKLGQIASTRQDLIPKD
IIEELEKLQDQVAPFSFSDVKEIIDKELQEPIDVVFESFDEDPIAAASIGQVHYGVLRTGQEVAVKIQRPNLEEKVHTDL
EILMNIAKLAESRLDWAKKYQLCAIIKEFSNSLTAELDYTLEGRNAHRIAQQFKKHDDVVVPNVYWDLTTEKVLTMEYIK
GIKLDENTKLVREGYNPKLIAEKLIQKQFQQILIDGFFHADPHPGNVMVLPNHKILFMDFGMVGRLTATMKDHLSSLIVA
IMRQNTKSIIKAIYRMGIVSEGVDADYMYADIDDLRDKYYDIPFSQVSIGEAINDLFRVATTHGIRIPTDLSLVGKSLLT
LEGTVERLDPDISIVKIAEPFGKRLLREKYQPKKVADEVYQQAEDYKDLILDFPDHINHLYKVIRRGKLPLEISVSRVEA
FLKKLDRISNRLSFSIVLLAFSIIMVGLIIGSALAGESSYLWSLPVIEIGFVVAIGMFLWLLYSIFRSGRF

Sequences:

>Translated_551_residues
MQRYREIVVAFSRNGFGYIVKELGLHKISSLPKRLFEQGDREVHNKTTGERIRLFLEELGPTFIKLGQIASTRQDLIPKD
IIEELEKLQDQVAPFSFSDVKEIIDKELQEPIDVVFESFDEDPIAAASIGQVHYGVLRTGQEVAVKIQRPNLEEKVHTDL
EILMNIAKLAESRLDWAKKYQLCAIIKEFSNSLTAELDYTLEGRNAHRIAQQFKKHDDVVVPNVYWDLTTEKVLTMEYIK
GIKLDENTKLVREGYNPKLIAEKLIQKQFQQILIDGFFHADPHPGNVMVLPNHKILFMDFGMVGRLTATMKDHLSSLIVA
IMRQNTKSIIKAIYRMGIVSEGVDADYMYADIDDLRDKYYDIPFSQVSIGEAINDLFRVATTHGIRIPTDLSLVGKSLLT
LEGTVERLDPDISIVKIAEPFGKRLLREKYQPKKVADEVYQQAEDYKDLILDFPDHINHLYKVIRRGKLPLEISVSRVEA
FLKKLDRISNRLSFSIVLLAFSIIMVGLIIGSALAGESSYLWSLPVIEIGFVVAIGMFLWLLYSIFRSGRF
>Mature_551_residues
MQRYREIVVAFSRNGFGYIVKELGLHKISSLPKRLFEQGDREVHNKTTGERIRLFLEELGPTFIKLGQIASTRQDLIPKD
IIEELEKLQDQVAPFSFSDVKEIIDKELQEPIDVVFESFDEDPIAAASIGQVHYGVLRTGQEVAVKIQRPNLEEKVHTDL
EILMNIAKLAESRLDWAKKYQLCAIIKEFSNSLTAELDYTLEGRNAHRIAQQFKKHDDVVVPNVYWDLTTEKVLTMEYIK
GIKLDENTKLVREGYNPKLIAEKLIQKQFQQILIDGFFHADPHPGNVMVLPNHKILFMDFGMVGRLTATMKDHLSSLIVA
IMRQNTKSIIKAIYRMGIVSEGVDADYMYADIDDLRDKYYDIPFSQVSIGEAINDLFRVATTHGIRIPTDLSLVGKSLLT
LEGTVERLDPDISIVKIAEPFGKRLLREKYQPKKVADEVYQQAEDYKDLILDFPDHINHLYKVIRRGKLPLEISVSRVEA
FLKKLDRISNRLSFSIVLLAFSIIMVGLIIGSALAGESSYLWSLPVIEIGFVVAIGMFLWLLYSIFRSGRF

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=301, Percent_Identity=30.5647840531561, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI41393593, Length=287, Percent_Identity=31.7073170731707, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI217035081, Length=236, Percent_Identity=31.7796610169492, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI27363457, Length=289, Percent_Identity=25.6055363321799, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217416386, Length=230, Percent_Identity=27.8260869565217, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI34147522, Length=411, Percent_Identity=24.0875912408759, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI32261307, Length=322, Percent_Identity=22.9813664596273, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI2367309, Length=520, Percent_Identity=29.4230769230769, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17559152, Length=312, Percent_Identity=30.1282051282051, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI32565180, Length=319, Percent_Identity=26.3322884012539, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555620, Length=472, Percent_Identity=20.5508474576271, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325148, Length=435, Percent_Identity=24.367816091954, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321319, Length=240, Percent_Identity=30.4166666666667, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323282, Length=247, Percent_Identity=27.9352226720648, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24662575, Length=309, Percent_Identity=30.7443365695793, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI22024280, Length=280, Percent_Identity=30, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18859849, Length=296, Percent_Identity=23.3108108108108, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62992; Mature: 62992

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRYREIVVAFSRNGFGYIVKELGLHKISSLPKRLFEQGDREVHNKTTGERIRLFLEELG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHC
PTFIKLGQIASTRQDLIPKDIIEELEKLQDQVAPFSFSDVKEIIDKELQEPIDVVFESFD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EDPIAAASIGQVHYGVLRTGQEVAVKIQRPNLEEKVHTDLEILMNIAKLAESRLDWAKKY
CCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLCAIIKEFSNSLTAELDYTLEGRNAHRIAQQFKKHDDVVVPNVYWDLTTEKVLTMEYIK
HHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCEECCCEEECCCHHHHHHHHHHC
GIKLDENTKLVREGYNPKLIAEKLIQKQFQQILIDGFFHADPHPGNVMVLPNHKILFMDF
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEC
GMVGRLTATMKDHLSSLIVAIMRQNTKSIIKAIYRMGIVSEGVDADYMYADIDDLRDKYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHC
DIPFSQVSIGEAINDLFRVATTHGIRIPTDLSLVGKSLLTLEGTVERLDPDISIVKIAEP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
FGKRLLREKYQPKKVADEVYQQAEDYKDLILDFPDHINHLYKVIRRGKLPLEISVSRVEA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHH
FLKKLDRISNRLSFSIVLLAFSIIMVGLIIGSALAGESSYLWSLPVIEIGFVVAIGMFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHH
LLYSIFRSGRF
HHHHHHHCCCC
>Mature Secondary Structure
MQRYREIVVAFSRNGFGYIVKELGLHKISSLPKRLFEQGDREVHNKTTGERIRLFLEELG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHC
PTFIKLGQIASTRQDLIPKDIIEELEKLQDQVAPFSFSDVKEIIDKELQEPIDVVFESFD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
EDPIAAASIGQVHYGVLRTGQEVAVKIQRPNLEEKVHTDLEILMNIAKLAESRLDWAKKY
CCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLCAIIKEFSNSLTAELDYTLEGRNAHRIAQQFKKHDDVVVPNVYWDLTTEKVLTMEYIK
HHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHCCCEECCCEEECCCHHHHHHHHHHC
GIKLDENTKLVREGYNPKLIAEKLIQKQFQQILIDGFFHADPHPGNVMVLPNHKILFMDF
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEC
GMVGRLTATMKDHLSSLIVAIMRQNTKSIIKAIYRMGIVSEGVDADYMYADIDDLRDKYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHC
DIPFSQVSIGEAINDLFRVATTHGIRIPTDLSLVGKSLLTLEGTVERLDPDISIVKIAEP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
FGKRLLREKYQPKKVADEVYQQAEDYKDLILDFPDHINHLYKVIRRGKLPLEISVSRVEA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHH
FLKKLDRISNRLSFSIVLLAFSIIMVGLIIGSALAGESSYLWSLPVIEIGFVVAIGMFLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHH
LLYSIFRSGRF
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]