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The map label for this gene is sigV [H]

Identifier: 23098724

GI number: 23098724

Start: 1313327

End: 1313851

Strand: Direct

Name: sigV [H]

Synonym: OB1269

Alternate gene names: 23098724

Gene position: 1313327-1313851 (Clockwise)

Preceding gene: 23098723

Following gene: 23098725

Centisome position: 36.17

GC content: 30.48

Gene sequence:

>525_bases
ATGGACGAAGAAAAAAAGATACAAATATTAGAAGAGGTGATGTTAGAGTACGGGAATGATTTAGTAAGATTAGCATTTAA
TTATGTGAAGGATAAAGAAACTGCAAAAGATATGGTCCAAGAGACATTTATTAAATGCTATGAAAAATTAGATGAATTCC
GTAATGAATCTAACTTAAAAACATGGTTATACAGGATAACTATTAATCAATGTAAGGATTATCTAAGGAGCTGGCATTAT
AGAAAAGTACAGACCAAAAGTGTTATTGAGAATACGTTTCGCACCGTATTTCCTTTAACTGAAGAAAAAATTATAAACCA
GGCAAATACAGAAGAAATGTTAGAGATTGTAGCATCATTGACAAAAAACTACCGTGAAATTATTTACTTATATTATTATA
AATCATTAACAATTAGTGAGATTACTGATGTCACAGGTTTGAACGAAAATACAGTGAAAACCAGATTGAGAAGGGCAAAA
CAACGCTTAAAAACTATGATGAAGGAGGCTGACATATATGGATAG

Upstream 100 bases:

>100_bases
TTCAGTTTTTCTGATTTCATGCGCTTTTTTATCTACAATTTGAAACAATTTTTCTTTGAAATTCGTCTAAAGGAAAAAAG
TTAAGAAAAGAGGGGGAGTT

Downstream 100 bases:

>100_bases
GGATAAAAAGAATTCTTCACTAGAAGATTATAACTTGTTTTTTACAAAGAAAGATAGAGAAGAAACATTAAAGAAAATTA
AGGATGGAACACAGTATAAA

Product: RNA polymerase factor sigma C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDEEKKIQILEEVMLEYGNDLVRLAFNYVKDKETAKDMVQETFIKCYEKLDEFRNESNLKTWLYRITINQCKDYLRSWHY
RKVQTKSVIENTFRTVFPLTEEKIINQANTEEMLEIVASLTKNYREIIYLYYYKSLTISEITDVTGLNENTVKTRLRRAK
QRLKTMMKEADIYG

Sequences:

>Translated_174_residues
MDEEKKIQILEEVMLEYGNDLVRLAFNYVKDKETAKDMVQETFIKCYEKLDEFRNESNLKTWLYRITINQCKDYLRSWHY
RKVQTKSVIENTFRTVFPLTEEKIINQANTEEMLEIVASLTKNYREIIYLYYYKSLTISEITDVTGLNENTVKTRLRRAK
QRLKTMMKEADIYG
>Mature_174_residues
MDEEKKIQILEEVMLEYGNDLVRLAFNYVKDKETAKDMVQETFIKCYEKLDEFRNESNLKTWLYRITINQCKDYLRSWHY
RKVQTKSVIENTFRTVFPLTEEKIINQANTEEMLEIVASLTKNYREIIYLYYYKSLTISEITDVTGLNENTVKTRLRRAK
QRLKTMMKEADIYG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=160, Percent_Identity=31.875, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20988; Mature: 20988

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEEKKIQILEEVMLEYGNDLVRLAFNYVKDKETAKDMVQETFIKCYEKLDEFRNESNLK
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TWLYRITINQCKDYLRSWHYRKVQTKSVIENTFRTVFPLTEEKIINQANTEEMLEIVASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
TKNYREIIYLYYYKSLTISEITDVTGLNENTVKTRLRRAKQRLKTMMKEADIYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDEEKKIQILEEVMLEYGNDLVRLAFNYVKDKETAKDMVQETFIKCYEKLDEFRNESNLK
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TWLYRITINQCKDYLRSWHYRKVQTKSVIENTFRTVFPLTEEKIINQANTEEMLEIVASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHH
TKNYREIIYLYYYKSLTISEITDVTGLNENTVKTRLRRAKQRLKTMMKEADIYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]