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The map label for this gene is hisK [H]

Identifier: 23098009

GI number: 23098009

Start: 585937

End: 586740

Strand: Direct

Name: hisK [H]

Synonym: OB0554

Alternate gene names: 23098009

Gene position: 585937-586740 (Clockwise)

Preceding gene: 23097999

Following gene: 23098010

Centisome position: 16.14

GC content: 36.19

Gene sequence:

>804_bases
ATGTTTGATTTTCATATGCATAGTAATTTTTCCGCGGATGGAGATTTTGAAATGGAGGCAATGGTGCAATCTGCTATACA
AAAAGGACTAAAAGAAATTTGCTTTACAGATCATTTAGATATAGATTATCCAGATAAAGATTGGGATTTTACATTTGACC
CGGTTAGATACACAGAGACAATCGAACAATTACAAGAAAAGTATCAAAACAAAATAACCATCCTTAAGGGAGTAGAGGTT
GGGGTGCAACCGCATGTATTACATGCGACAGCTGATTTTGTAAACAGCTTGCAGCCTGACTTTGTTATTTGTTCCATGCA
TGCAACGAGGGGTACAGACCTGCATTCTGGTGAATTTTTTCAAGAGAAATCAATAGAGACTGCTTTCCGGCAATATTTTG
AAGAATTGTATGCGTGTATACAGAAATTTGATTCATACCAAGTATTGGGACATGTTGATTTGGTGAGACGATATGCAAAG
CAGACAAGTAAGGATGAATGCTTCGACATTCTTGAATCCATTTTGAAGCTTGTAATTAATCAGCGTAAAGGTATTGAATT
AAACACTTCAGGATTTAAGTATGGGTTAGAGGCAGGACTACCGAGTAAAGAAATTTTAGAACTGTATCATCAACTGGGAG
GGGAGATACTAACTATTGGTTCGGATGCTCACCGTCCAAACGAAATATCACAAAGCTTCCGTCAATCATTAGAACTATTG
CAATCCATTGGATTTAATTATATTACTTCGTTTGAAGAGCAAGTACCCAAGTTTACTTCTATTGAGAAAGTAAAAAATAT
CTAG

Upstream 100 bases:

>100_bases
CTATAATTTCTTTAGTATTTTACCGCTTTATCACTTTATCTAAGTAAAGTTATATAGTATTATATAAATAATCAGAAAAA
ATGTCAATGGAGGGTTAAAA

Downstream 100 bases:

>100_bases
AAAATAATCGTATTGGTGTTTGTGATTGTGAAGGAATGGTATAATAACGTGAAGAAATTAAACCTATTACATTCGAAGTG
AATGTTGGTAAAGTTATAAA

Product: histidinol phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MFDFHMHSNFSADGDFEMEAMVQSAIQKGLKEICFTDHLDIDYPDKDWDFTFDPVRYTETIEQLQEKYQNKITILKGVEV
GVQPHVLHATADFVNSLQPDFVICSMHATRGTDLHSGEFFQEKSIETAFRQYFEELYACIQKFDSYQVLGHVDLVRRYAK
QTSKDECFDILESILKLVINQRKGIELNTSGFKYGLEAGLPSKEILELYHQLGGEILTIGSDAHRPNEISQSFRQSLELL
QSIGFNYITSFEEQVPKFTSIEKVKNI

Sequences:

>Translated_267_residues
MFDFHMHSNFSADGDFEMEAMVQSAIQKGLKEICFTDHLDIDYPDKDWDFTFDPVRYTETIEQLQEKYQNKITILKGVEV
GVQPHVLHATADFVNSLQPDFVICSMHATRGTDLHSGEFFQEKSIETAFRQYFEELYACIQKFDSYQVLGHVDLVRRYAK
QTSKDECFDILESILKLVINQRKGIELNTSGFKYGLEAGLPSKEILELYHQLGGEILTIGSDAHRPNEISQSFRQSLELL
QSIGFNYITSFEEQVPKFTSIEKVKNI
>Mature_267_residues
MFDFHMHSNFSADGDFEMEAMVQSAIQKGLKEICFTDHLDIDYPDKDWDFTFDPVRYTETIEQLQEKYQNKITILKGVEV
GVQPHVLHATADFVNSLQPDFVICSMHATRGTDLHSGEFFQEKSIETAFRQYFEELYACIQKFDSYQVLGHVDLVRRYAK
QTSKDECFDILESILKLVINQRKGIELNTSGFKYGLEAGLPSKEILELYHQLGGEILTIGSDAHRPNEISQSFRQSLELL
QSIGFNYITSFEEQVPKFTSIEKVKNI

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30792; Mature: 30792

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFHMHSNFSADGDFEMEAMVQSAIQKGLKEICFTDHLDIDYPDKDWDFTFDPVRYTET
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IEQLQEKYQNKITILKGVEVGVQPHVLHATADFVNSLQPDFVICSMHATRGTDLHSGEFF
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHH
QEKSIETAFRQYFEELYACIQKFDSYQVLGHVDLVRRYAKQTSKDECFDILESILKLVIN
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
QRKGIELNTSGFKYGLEAGLPSKEILELYHQLGGEILTIGSDAHRPNEISQSFRQSLELL
CCCCCEECCCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
QSIGFNYITSFEEQVPKFTSIEKVKNI
HHCCCHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MFDFHMHSNFSADGDFEMEAMVQSAIQKGLKEICFTDHLDIDYPDKDWDFTFDPVRYTET
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IEQLQEKYQNKITILKGVEVGVQPHVLHATADFVNSLQPDFVICSMHATRGTDLHSGEFF
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHH
QEKSIETAFRQYFEELYACIQKFDSYQVLGHVDLVRRYAKQTSKDECFDILESILKLVIN
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
QRKGIELNTSGFKYGLEAGLPSKEILELYHQLGGEILTIGSDAHRPNEISQSFRQSLELL
CCCCCEECCCCCHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
QSIGFNYITSFEEQVPKFTSIEKVKNI
HHCCCHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400209; 11337471 [H]