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The map label for this gene is aroD [H]

Identifier: 23097885

GI number: 23097885

Start: 456497

End: 457270

Strand: Direct

Name: aroD [H]

Synonym: OB0430

Alternate gene names: 23097885

Gene position: 456497-457270 (Clockwise)

Preceding gene: 23097881

Following gene: 23097886

Centisome position: 12.57

GC content: 36.82

Gene sequence:

>774_bases
ATGAAGAATGTTGTTCATGTGAAGAATATCAATATCGGTGAGGGGAAACCGAAAGTGTGTGTTCCGATAACGGGAGCTAC
AAAGAAAGAAATAAGTGAGGAGTTAGATCTACTGCAAACCATAAAAGTCGACCTAGTGGAATGGCGGGGAGATTTATTCC
AAGAAATTGAAAATGAAATATCGGTTAAAAACATGCTGCAAAAAATAAATCAAGAAATCCCTCACCTTCCGTTATTATTT
ACTTTTCGGACAAAAGGAGAAGGCGGTGGAAGGGAAGTCACGCTGGAAAAATATAAAGAAATTAATCGTTTTGTTATTGA
ATCAAAACTAGTCGACTTGGTTGATGTTGAATTATTTCGTGGTAAGAACTTAGTAAAAGAACTTGTTTCTTTTGCTCATC
TGCATGACCAAAAGGTAATTATTTCTAATCATGATTTTAATCAGACACCTCCACGTGATGAGATCATAGCACGTCTAAAA
TTAGCAGCTGATAACGGGGCTGATATTGGAAAAATTGCAGTAATGCCTCGTAACGATGAAGATGTGTTGAATTTACTTTC
TGCAACATCACTTGTGAAAGAATTGAATCATATTCCGATCGTCACCATGTCGATGGGAGCTGATGGATTGATTAGTCGCT
TATCTGGTGAAGTATTTGGTTCAGCAATTACTTTTGCTTCTGGGAAAACAGCTTCAGCACCAGGACAGATTGAAGCTGAA
AAATTACAAACCGTGCTAACGATTATCCATGATTCTATAAATAAGAAAAAGTAG

Upstream 100 bases:

>100_bases
TATATACTCATGTGTATAACTATAAGTCTAAAAATGATTAAAGTCAATAGGCAAGCGGAATTTTTTGATATACTATGGTG
ATAAAAGGGGTGGAGCGTAA

Downstream 100 bases:

>100_bases
AGGTTGGTACAAGGGATTTACTCAAAAGATGTATTCAAATGCTGGTTTTCATAACCGGATTCAGAAGTGTACTACGTTTG
TGTAACGGTAAGGGGTGAGG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKNVVHVKNINIGEGKPKVCVPITGATKKEISEELDLLQTIKVDLVEWRGDLFQEIENEISVKNMLQKINQEIPHLPLLF
TFRTKGEGGGREVTLEKYKEINRFVIESKLVDLVDVELFRGKNLVKELVSFAHLHDQKVIISNHDFNQTPPRDEIIARLK
LAADNGADIGKIAVMPRNDEDVLNLLSATSLVKELNHIPIVTMSMGADGLISRLSGEVFGSAITFASGKTASAPGQIEAE
KLQTVLTIIHDSINKKK

Sequences:

>Translated_257_residues
MKNVVHVKNINIGEGKPKVCVPITGATKKEISEELDLLQTIKVDLVEWRGDLFQEIENEISVKNMLQKINQEIPHLPLLF
TFRTKGEGGGREVTLEKYKEINRFVIESKLVDLVDVELFRGKNLVKELVSFAHLHDQKVIISNHDFNQTPPRDEIIARLK
LAADNGADIGKIAVMPRNDEDVLNLLSATSLVKELNHIPIVTMSMGADGLISRLSGEVFGSAITFASGKTASAPGQIEAE
KLQTVLTIIHDSINKKK
>Mature_257_residues
MKNVVHVKNINIGEGKPKVCVPITGATKKEISEELDLLQTIKVDLVEWRGDLFQEIENEISVKNMLQKINQEIPHLPLLF
TFRTKGEGGGREVTLEKYKEINRFVIESKLVDLVDVELFRGKNLVKELVSFAHLHDQKVIISNHDFNQTPPRDEIIARLK
LAADNGADIGKIAVMPRNDEDVLNLLSATSLVKELNHIPIVTMSMGADGLISRLSGEVFGSAITFASGKTASAPGQIEAE
KLQTVLTIIHDSINKKK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=253, Percent_Identity=46.6403162055336, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 28519; Mature: 28519

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVVHVKNINIGEGKPKVCVPITGATKKEISEELDLLQTIKVDLVEWRGDLFQEIENEI
CCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKNMLQKINQEIPHLPLLFTFRTKGEGGGREVTLEKYKEINRFVIESKLVDLVDVELFR
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKNLVKELVSFAHLHDQKVIISNHDFNQTPPRDEIIARLKLAADNGADIGKIAVMPRNDE
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCHH
DVLNLLSATSLVKELNHIPIVTMSMGADGLISRLSGEVFGSAITFASGKTASAPGQIEAE
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHH
KLQTVLTIIHDSINKKK
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNVVHVKNINIGEGKPKVCVPITGATKKEISEELDLLQTIKVDLVEWRGDLFQEIENEI
CCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVKNMLQKINQEIPHLPLLFTFRTKGEGGGREVTLEKYKEINRFVIESKLVDLVDVELFR
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKNLVKELVSFAHLHDQKVIISNHDFNQTPPRDEIIARLKLAADNGADIGKIAVMPRNDE
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCHH
DVLNLLSATSLVKELNHIPIVTMSMGADGLISRLSGEVFGSAITFASGKTASAPGQIEAE
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHH
KLQTVLTIIHDSINKKK
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA