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The map label for this gene is gpo [H]

Identifier: 229918281

GI number: 229918281

Start: 2524524

End: 2524997

Strand: Reverse

Name: gpo [H]

Synonym: EAT1b_2564

Alternate gene names: 229918281

Gene position: 2524997-2524524 (Counterclockwise)

Preceding gene: 229918284

Following gene: 229918280

Centisome position: 84.17

GC content: 46.84

Gene sequence:

>474_bases
ATGATTTATGATTTTGAAGCAGTAGACATGAAAGGACAATTGCAACCGTTAGCTACATATAAAGGCGACGTCTTACTCAT
CGTCAACACGGCGAGCAAATGTGGGTTCACACCACAGCTCGAAGGTCTCGAGTCACTTTACAAAACATATAAGGGACAGG
GCCTACAGATCTTAGGTTTCCCGTGCAACCAGTTCGGTCATCAAGACCCGGGCTCCAATGAAGAAATTCAAGAGTTCTGT
CAACTTAACTATGGCGTATCGTTCCCGATGTTTGCGAAAGTCGATGTGAACGGAAAAGACGCCCATCCGCTCTTCACTTA
TCTCTCAAAAGAAGCACCCGGGCTTCTGGGGTCGAAGGCGATCAAATGGAATTTCACAAAGTTTTTAGTCGATCGCGACG
GGAACGTCATCGAGCGCTTTTCGCCACAAACGACACCGGCTGAGATTGAGGATGCGGTCAAAAAACTGATTTGA

Upstream 100 bases:

>100_bases
AGCGACATCATGATTTCATAACAATTTGATTGCACGCAACGCGTTTAAAGTCGAGATAGCGGATTTCTCTTGGTATACTA
CAAAAAAAGGGGGAATAAAC

Downstream 100 bases:

>100_bases
CCTCATCCTGAAGGCGTAGATTGATTTCTCTCTACGGTCTAATTGGCGTTTACACTTAAGCCATCTATCATATTCTATGC
ACAGTAAATCGTGAAGGAGT

Product: Peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MIYDFEAVDMKGQLQPLATYKGDVLLIVNTASKCGFTPQLEGLESLYKTYKGQGLQILGFPCNQFGHQDPGSNEEIQEFC
QLNYGVSFPMFAKVDVNGKDAHPLFTYLSKEAPGLLGSKAIKWNFTKFLVDRDGNVIERFSPQTTPAEIEDAVKKLI

Sequences:

>Translated_157_residues
MIYDFEAVDMKGQLQPLATYKGDVLLIVNTASKCGFTPQLEGLESLYKTYKGQGLQILGFPCNQFGHQDPGSNEEIQEFC
QLNYGVSFPMFAKVDVNGKDAHPLFTYLSKEAPGLLGSKAIKWNFTKFLVDRDGNVIERFSPQTTPAEIEDAVKKLI
>Mature_157_residues
MIYDFEAVDMKGQLQPLATYKGDVLLIVNTASKCGFTPQLEGLESLYKTYKGQGLQILGFPCNQFGHQDPGSNEEIQEFC
QLNYGVSFPMFAKVDVNGKDAHPLFTYLSKEAPGLLGSKAIKWNFTKFLVDRDGNVIERFSPQTTPAEIEDAVKKLI

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=42.9487179487179, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI75709200, Length=152, Percent_Identity=47.3684210526316, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI90903240, Length=152, Percent_Identity=47.3684210526316, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=48.4615384615385, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI192455698, Length=148, Percent_Identity=38.5135135135135, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI4557629, Length=172, Percent_Identity=36.6279069767442, Blast_Score=100, Evalue=4e-22,
Organism=Homo sapiens, GI6006001, Length=169, Percent_Identity=36.6863905325444, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI41406084, Length=181, Percent_Identity=33.1491712707182, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=31.3186813186813, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI33186887, Length=174, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788003, Length=159, Percent_Identity=46.5408805031447, Blast_Score=155, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=44.5859872611465, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17535473, Length=154, Percent_Identity=42.8571428571429, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=44.0993788819876, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=36.3057324840764, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=162, Percent_Identity=32.0987654320988, Blast_Score=102, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI193209493, Length=162, Percent_Identity=32.0987654320988, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=40, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=32.9787234042553, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193210709, Length=73, Percent_Identity=47.945205479452, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=155, Percent_Identity=55.4838709677419, Blast_Score=192, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319721, Length=155, Percent_Identity=56.1290322580645, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=45.1612903225806, Blast_Score=151, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=47.1698113207547, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=47.1698113207547, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=47.1698113207547, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=41.1392405063291, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17504; Mature: 17504

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYDFEAVDMKGQLQPLATYKGDVLLIVNTASKCGFTPQLEGLESLYKTYKGQGLQILGF
CCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
PCNQFGHQDPGSNEEIQEFCQLNYGVSFPMFAKVDVNGKDAHPLFTYLSKEAPGLLGSKA
CCHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCE
IKWNFTKFLVDRDGNVIERFSPQTTPAEIEDAVKKLI
EEEEHEEEEEECCCCEEECCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIYDFEAVDMKGQLQPLATYKGDVLLIVNTASKCGFTPQLEGLESLYKTYKGQGLQILGF
CCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
PCNQFGHQDPGSNEEIQEFCQLNYGVSFPMFAKVDVNGKDAHPLFTYLSKEAPGLLGSKA
CCHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCE
IKWNFTKFLVDRDGNVIERFSPQTTPAEIEDAVKKLI
EEEEHEEEEEECCCCEEECCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]