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The map label for this gene is dinB [H]

Identifier: 229918168

GI number: 229918168

Start: 2405558

End: 2406649

Strand: Reverse

Name: dinB [H]

Synonym: EAT1b_2448

Alternate gene names: 229918168

Gene position: 2406649-2405558 (Counterclockwise)

Preceding gene: 229918169

Following gene: 229918167

Centisome position: 80.22

GC content: 51.83

Gene sequence:

>1092_bases
ATGGAACGACTCATCATTCATGTGGACATGGACGCATTTTATGCCTCTGTCGAACAGCGTGACCGTCCTAACTTACGAGG
AAAGCCCGTCATCGTAGGAGGTCCTCCCCACAGCCGTGGGGTCGTTGCGACATGTTCCTATGAGGCGAGGAAATACGGCG
TACACAGTGCGATGTCATCACGTCGCGCTTTTGCCTTGTGTCCCCATGCGACGTTTGTCAAACCACGGTTTCAGGCCTAT
CGACAAGTCAGCGCACAAGTGATGGAGATTTTTAAGTCCGTCACACCGCTCGTCGAACCACTCTCGCTCGATGAGGCTTA
TCTCGATGTGACGGAGAATTCGTTATTGAGCACATCTGGACCCTTTATCGCCCGGTATATCTTAGGCGAAATTAAGCGTC
GCACCGGTCTCACCGCGTCTGCCGGAGTCGCACCGTCAAAGTTTGTCGCGAAAATCGCTTCAGGATTTGAGAAACCAAAT
GGACTCACCGTCGTCCCGCTTGATGAAGTGGCAACCTTTCTCGCTCCCCTCTCCATCGAAGCCATGCATGGCGTCGGAAA
AGTGACCGCTCAAACACTTTATAAAAGTGGCTACCATACGATTGGTGACCTTCAACAAACTCGTCCCGAGCAACTGAAAG
GCATCTTTGGACACGATCGTGGGCAACAACTGTATGAACTGGCACATGGACGCGATACGCGCCCTGTCGTGGCCATGCGG
GAGCGTAAGTCGATTGGATCAGAAACGACGTTCGCATTTGATATCGATGACCCGGAAGAAGTGTTCGAACGGGTCATTCC
GGAGATGGAGGACGTATTGCGTCAGCTCGATCGCCGCGACTTGAGCTGTCAAACGGTCACCATCAAAATAAAGACGAGCG
AGTTTCAGGCTCGGAGTCATCAAATCAAATTAAACCACCCGACGCATGACCATGATGAGATTAGACGACTTGCCAGACGT
CTTTTCGACGAGATGAACGTCACCGAGCCCGTCCGCTTGATCGGACTGACCGTATCCGATTTGATTCCCCGAACTGAATC
GACACGACAGCTGACATTCGACGAACTGACAAAACCTTCTCTTGAAGAATGA

Upstream 100 bases:

>100_bases
AACGACTTCAACGAAACATCGGGCAAAACAAAATTCTCAAAAAACGAACAAAAGTTCGGTATAATGAAAGAAAAGTGATT
CACACAAGAAAGGTGATGTT

Downstream 100 bases:

>100_bases
ATGACCATTCATTAAAATGAAGAAAAGGGGGGTCGTGTGAATGGAAACATACACGGTGACAGGATTTGAAAATGATGGCA
CGCTCGTATTGAATGAAATG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MERLIIHVDMDAFYASVEQRDRPNLRGKPVIVGGPPHSRGVVATCSYEARKYGVHSAMSSRRAFALCPHATFVKPRFQAY
RQVSAQVMEIFKSVTPLVEPLSLDEAYLDVTENSLLSTSGPFIARYILGEIKRRTGLTASAGVAPSKFVAKIASGFEKPN
GLTVVPLDEVATFLAPLSIEAMHGVGKVTAQTLYKSGYHTIGDLQQTRPEQLKGIFGHDRGQQLYELAHGRDTRPVVAMR
ERKSIGSETTFAFDIDDPEEVFERVIPEMEDVLRQLDRRDLSCQTVTIKIKTSEFQARSHQIKLNHPTHDHDEIRRLARR
LFDEMNVTEPVRLIGLTVSDLIPRTESTRQLTFDELTKPSLEE

Sequences:

>Translated_363_residues
MERLIIHVDMDAFYASVEQRDRPNLRGKPVIVGGPPHSRGVVATCSYEARKYGVHSAMSSRRAFALCPHATFVKPRFQAY
RQVSAQVMEIFKSVTPLVEPLSLDEAYLDVTENSLLSTSGPFIARYILGEIKRRTGLTASAGVAPSKFVAKIASGFEKPN
GLTVVPLDEVATFLAPLSIEAMHGVGKVTAQTLYKSGYHTIGDLQQTRPEQLKGIFGHDRGQQLYELAHGRDTRPVVAMR
ERKSIGSETTFAFDIDDPEEVFERVIPEMEDVLRQLDRRDLSCQTVTIKIKTSEFQARSHQIKLNHPTHDHDEIRRLARR
LFDEMNVTEPVRLIGLTVSDLIPRTESTRQLTFDELTKPSLEE
>Mature_363_residues
MERLIIHVDMDAFYASVEQRDRPNLRGKPVIVGGPPHSRGVVATCSYEARKYGVHSAMSSRRAFALCPHATFVKPRFQAY
RQVSAQVMEIFKSVTPLVEPLSLDEAYLDVTENSLLSTSGPFIARYILGEIKRRTGLTASAGVAPSKFVAKIASGFEKPN
GLTVVPLDEVATFLAPLSIEAMHGVGKVTAQTLYKSGYHTIGDLQQTRPEQLKGIFGHDRGQQLYELAHGRDTRPVVAMR
ERKSIGSETTFAFDIDDPEEVFERVIPEMEDVLRQLDRRDLSCQTVTIKIKTSEFQARSHQIKLNHPTHDHDEIRRLARR
LFDEMNVTEPVRLIGLTVSDLIPRTESTRQLTFDELTKPSLEE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=411, Percent_Identity=28.2238442822384, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI7706681, Length=412, Percent_Identity=28.1553398058252, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI154350220, Length=285, Percent_Identity=31.9298245614035, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI7705344, Length=181, Percent_Identity=37.0165745856354, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI5729982, Length=168, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786425, Length=354, Percent_Identity=43.5028248587571, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787432, Length=376, Percent_Identity=24.7340425531915, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=405, Percent_Identity=27.6543209876543, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17537959, Length=370, Percent_Identity=26.7567567567568, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115534089, Length=126, Percent_Identity=39.6825396825397, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=340, Percent_Identity=25.8823529411765, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=316, Percent_Identity=22.7848101265823, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19923006, Length=394, Percent_Identity=26.3959390862944, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI21355641, Length=424, Percent_Identity=27.8301886792453, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24644984, Length=424, Percent_Identity=27.8301886792453, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=33.6134453781513, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40799; Mature: 40799

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLIIHVDMDAFYASVEQRDRPNLRGKPVIVGGPPHSRGVVATCSYEARKYGVHSAMSS
CCEEEEEECHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHC
RRAFALCPHATFVKPRFQAYRQVSAQVMEIFKSVTPLVEPLSLDEAYLDVTENSLLSTSG
CCEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCCC
PFIARYILGEIKRRTGLTASAGVAPSKFVAKIASGFEKPNGLTVVPLDEVATFLAPLSIE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCHHH
AMHGVGKVTAQTLYKSGYHTIGDLQQTRPEQLKGIFGHDRGQQLYELAHGRDTRPVVAMR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
ERKSIGSETTFAFDIDDPEEVFERVIPEMEDVLRQLDRRDLSCQTVTIKIKTSEFQARSH
HHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCC
QIKLNHPTHDHDEIRRLARRLFDEMNVTEPVRLIGLTVSDLIPRTESTRQLTFDELTKPS
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCCCCCCCCHHHCCCCC
LEE
CCC
>Mature Secondary Structure
MERLIIHVDMDAFYASVEQRDRPNLRGKPVIVGGPPHSRGVVATCSYEARKYGVHSAMSS
CCEEEEEECHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHC
RRAFALCPHATFVKPRFQAYRQVSAQVMEIFKSVTPLVEPLSLDEAYLDVTENSLLSTSG
CCEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCCC
PFIARYILGEIKRRTGLTASAGVAPSKFVAKIASGFEKPNGLTVVPLDEVATFLAPLSIE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCHHH
AMHGVGKVTAQTLYKSGYHTIGDLQQTRPEQLKGIFGHDRGQQLYELAHGRDTRPVVAMR
HHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
ERKSIGSETTFAFDIDDPEEVFERVIPEMEDVLRQLDRRDLSCQTVTIKIKTSEFQARSH
HHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHHCCCC
QIKLNHPTHDHDEIRRLARRLFDEMNVTEPVRLIGLTVSDLIPRTESTRQLTFDELTKPS
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCCCCCCCCHHHCCCCC
LEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA