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The map label for this gene is plsC [H]

Identifier: 229918082

GI number: 229918082

Start: 2315176

End: 2315877

Strand: Reverse

Name: plsC [H]

Synonym: EAT1b_2361

Alternate gene names: 229918082

Gene position: 2315877-2315176 (Counterclockwise)

Preceding gene: 229918083

Following gene: 229918081

Centisome position: 77.2

GC content: 47.58

Gene sequence:

>702_bases
ATGATTCGAACAGCTGTATGGTTTTTCTCATTTTTTGCCGTATTACCAATCACCGTCCCGTTTTTACAGAAGGCGAAAAA
AATCGAAACACCGAAACGTTACCGTTACGTACAAGATATCGCTTATAAATGGGCACAGTTTCTACTAAAGATTGCGGGTG
CAAACGTCCGTGTACATGGTCAAGACCAGATTCCGGATGAACCCGTTGTCTACGTGTCGAACCACCAAGGAAACTTCGAC
GTCCCGATTATGTTGACCGCCACGAAACGACCGAAAGCGTTTATCTCGAAAATCGAGGTTCAAAAATTCCCGATTATCCC
ACGTTGGATGGAATTGATGGGGTGTATCTTCATCGACCGGAGTGACCGTCGGCAATCGATTCAAGCCATTCGTTCCGGTG
TCGAAACGATTCAATCCGGCCAATCAATGATTGTCTTCCCAGAAGGCACACGCTCAAAAGGTGGACCGATGAAGGAGTTT
AAAGCTGGAAGTTTGACGCTCGCCACATCAAGTGGTGCGAAGATTGTTCCAGTCGCGATTCAAGGCAGTTATAAATTGTT
AGAAGCCAAAAATCGAATCACCCCGGCAACGGTCGATGTCACATTCTTACCTGCGATTGATCCGGCCGATTTGCCGAACA
AGGAAATCGCAGCGACGGTCGAGGCGGCCATTCGTCAACAGCTTGAAGGAGAGAACGCATGA

Upstream 100 bases:

>100_bases
CGATTCTCGCTTTTGGGAATAAGGATTCATGCCGAAGGGTCGGATTCTCGTCAAGAGAAGAAGACTCTTTCTTGTTGTCA
TCATGAGAGGAGAGAATAGA

Downstream 100 bases:

>100_bases
GTTTATTAATGATTGAAGGCATTCATAAAGAGTTTGCCGACAAAGTCTTATTTGATGATGTGACGATGACGATCCATCCC
GGAGACCGTATCGGGATTAT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MIRTAVWFFSFFAVLPITVPFLQKAKKIETPKRYRYVQDIAYKWAQFLLKIAGANVRVHGQDQIPDEPVVYVSNHQGNFD
VPIMLTATKRPKAFISKIEVQKFPIIPRWMELMGCIFIDRSDRRQSIQAIRSGVETIQSGQSMIVFPEGTRSKGGPMKEF
KAGSLTLATSSGAKIVPVAIQGSYKLLEAKNRITPATVDVTFLPAIDPADLPNKEIAATVEAAIRQQLEGENA

Sequences:

>Translated_233_residues
MIRTAVWFFSFFAVLPITVPFLQKAKKIETPKRYRYVQDIAYKWAQFLLKIAGANVRVHGQDQIPDEPVVYVSNHQGNFD
VPIMLTATKRPKAFISKIEVQKFPIIPRWMELMGCIFIDRSDRRQSIQAIRSGVETIQSGQSMIVFPEGTRSKGGPMKEF
KAGSLTLATSSGAKIVPVAIQGSYKLLEAKNRITPATVDVTFLPAIDPADLPNKEIAATVEAAIRQQLEGENA
>Mature_233_residues
MIRTAVWFFSFFAVLPITVPFLQKAKKIETPKRYRYVQDIAYKWAQFLLKIAGANVRVHGQDQIPDEPVVYVSNHQGNFD
VPIMLTATKRPKAFISKIEVQKFPIIPRWMELMGCIFIDRSDRRQSIQAIRSGVETIQSGQSMIVFPEGTRSKGGPMKEF
KAGSLTLATSSGAKIVPVAIQGSYKLLEAKNRITPATVDVTFLPAIDPADLPNKEIAATVEAAIRQQLEGENA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=212, Percent_Identity=30.6603773584906, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15100175, Length=212, Percent_Identity=30.6603773584906, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789395, Length=163, Percent_Identity=28.2208588957055, Blast_Score=74, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=183, Percent_Identity=28.9617486338798, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364648, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582856, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582854, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 25979; Mature: 25979

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTAVWFFSFFAVLPITVPFLQKAKKIETPKRYRYVQDIAYKWAQFLLKIAGANVRVHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
QDQIPDEPVVYVSNHQGNFDVPIMLTATKRPKAFISKIEVQKFPIIPRWMELMGCIFIDR
CCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC
SDRRQSIQAIRSGVETIQSGQSMIVFPEGTRSKGGPMKEFKAGSLTLATSSGAKIVPVAI
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCEEEEEECCCCEEEEEEE
QGSYKLLEAKNRITPATVDVTFLPAIDPADLPNKEIAATVEAAIRQQLEGENA
CCCEEEEHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRTAVWFFSFFAVLPITVPFLQKAKKIETPKRYRYVQDIAYKWAQFLLKIAGANVRVHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
QDQIPDEPVVYVSNHQGNFDVPIMLTATKRPKAFISKIEVQKFPIIPRWMELMGCIFIDR
CCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC
SDRRQSIQAIRSGVETIQSGQSMIVFPEGTRSKGGPMKEFKAGSLTLATSSGAKIVPVAI
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCEEEEEECCCCEEEEEEE
QGSYKLLEAKNRITPATVDVTFLPAIDPADLPNKEIAATVEAAIRQQLEGENA
CCCEEEEHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]