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The map label for this gene is yqjC [H]

Identifier: 229918026

GI number: 229918026

Start: 2259371

End: 2259784

Strand: Reverse

Name: yqjC [H]

Synonym: EAT1b_2305

Alternate gene names: 229918026

Gene position: 2259784-2259371 (Counterclockwise)

Preceding gene: 229918028

Following gene: 229918024

Centisome position: 75.33

GC content: 49.03

Gene sequence:

>414_bases
ATGCATATCGATCATACTGGGATTGCCGTTCGAGACTTAGATGAGGCAATCACATTTTATACGACGGTCTTAGGAGGAAA
ACTCGTGGACCGCTATACGAACACGGCAATCGGGGTAGAGACCGAGTTGGCCGTCATTCATATTGGAGAGGATGTCATCG
AATTGTTACGTCCGACTAGTAAGACGAGTCCGATTGCCCGGTTCATGAAAGCTCGAGGGAAGGGTGTCCACCATATCGCC
TACCGTGTCGATGATTTGGATGAAGCGATTGCCGCTCACAAACAGAACGGCATCACCTTTTTAGAAGACACCCTGCGTAC
GACGGCGAAAGGTAGACGCTTAATCTACATGGACCCGCGACATTCAGGCGGTGTGATTACCGAGCTTTGTGATTACCCTA
AAGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
CGCTGTCCCTCCCTCTCCTATTATATCGGATAAGCGGGAAACGTTGTGAAGTGACATTTTGTTCAACTTTAGGCAAACTG
AAGAAGGAGGAGGAATGTAC

Downstream 100 bases:

>100_bases
GAGTCCCCCTCTTACTGCTTCATGATGGTTTCTTCTATAATTTGACGATTCTTCTCTTTCAACCGTTCATTGTGAGAGGA
CACCATTGCGGTAGCGGTGG

Product: Glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MHIDHTGIAVRDLDEAITFYTTVLGGKLVDRYTNTAIGVETELAVIHIGEDVIELLRPTSKTSPIARFMKARGKGVHHIA
YRVDDLDEAIAAHKQNGITFLEDTLRTTAKGRRLIYMDPRHSGGVITELCDYPKEKQ

Sequences:

>Translated_137_residues
MHIDHTGIAVRDLDEAITFYTTVLGGKLVDRYTNTAIGVETELAVIHIGEDVIELLRPTSKTSPIARFMKARGKGVHHIA
YRVDDLDEAIAAHKQNGITFLEDTLRTTAKGRRLIYMDPRHSGGVITELCDYPKEKQ
>Mature_137_residues
MHIDHTGIAVRDLDEAITFYTTVLGGKLVDRYTNTAIGVETELAVIHIGEDVIELLRPTSKTSPIARFMKARGKGVHHIA
YRVDDLDEAIAAHKQNGITFLEDTLRTTAKGRRLIYMDPRHSGGVITELCDYPKEKQ

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=128, Percent_Identity=33.59375, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506387, Length=128, Percent_Identity=34.375, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15315; Mature: 15315

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIDHTGIAVRDLDEAITFYTTVLGGKLVDRYTNTAIGVETELAVIHIGEDVIELLRPTS
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEEECHHHHHHHCCCC
KTSPIARFMKARGKGVHHIAYRVDDLDEAIAAHKQNGITFLEDTLRTTAKGRRLIYMDPR
CCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
HSGGVITELCDYPKEKQ
CCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MHIDHTGIAVRDLDEAITFYTTVLGGKLVDRYTNTAIGVETELAVIHIGEDVIELLRPTS
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEEECHHHHHHHCCCC
KTSPIARFMKARGKGVHHIAYRVDDLDEAIAAHKQNGITFLEDTLRTTAKGRRLIYMDPR
CCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCC
HSGGVITELCDYPKEKQ
CCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]