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The map label for this gene is adcA [H]

Identifier: 229917775

GI number: 229917775

Start: 2006423

End: 2007478

Strand: Reverse

Name: adcA [H]

Synonym: EAT1b_2053

Alternate gene names: 229917775

Gene position: 2007478-2006423 (Counterclockwise)

Preceding gene: 229917779

Following gene: 229917769

Centisome position: 66.92

GC content: 50.0

Gene sequence:

>1056_bases
ATGAAAAAGACATGGTTCGGCGCAGTCGCAGCCGGTACGCTTTTACTCGGTGCGTGCGGAAATACCGAAGGAGATAACGC
ATCTGAATCAACGGATGGTCAATTGACCGTTTACGCTTCAACGTTTGCATTAAAATCAATGGCCGAAGAAATCGGTGGGG
ACCGCGTCAACGTGGAGATGGTCATTCCACCTGGGGCTGACCCGCATACGTATGAGCCAACTTCAAAGCAAATGACACAA
ATCGCAGAAGCCGACCTCTTTTTGACGATTGGTCATGACCTTGAACCTTACGTCGAGTCTATGGAGAAGAGTTTAGAAGG
TCAGAACGTCGCTTTCGTCAAAACAGCTGAGAACGTGAAGTTACTCGATGCAGCGGATACCGTCCATGTCCATGATGAGG
AAGGACATACTGAAGACGAAGGGCACACCGAGGATGAGCACGCTCACGAAGAAGACGCACATTCTGAAGACGAAGGGCAT
TCTGAAGACGAGCATGCTAACGAAGAAGCATCACACTCGGAAGATGAGCATGACCACGGAAAGTATGACCCTCACGTTTG
GCTCGATCCAACGAATGCTGTATCGATGGCAGAAGCGGTCGAAGCCGCATTCAGTGAGGAAGCACCCGACTATAAGGATG
AGTTCGCAGAACGATTAAGCACCTTCAAAGACGAAGCGAACGCCCTCGATGCGGAATTGAGGGCAGCGGTCGAGAACGGT
TCGAAATCCGAGTTACTCGTAACGCATGCCGCATATGGCTATTTGGCTGAACGCTATGGTTTCGACCAATTGCCGATTGC
CGGACTCACACCGTCTGAAGAGCCGTCACAACAAGCTCTCAAACGGATTATCGAGGAAGCCCGCCTCCACGACTTGAACT
ATATCGCATTCGAAGACACGGTCACACCAAAAGTGGCCGAAGTCGTGAAACAAGAGATCGGCGCAGAGAGCGTGACAATC
TATAACTTGGAATCGGTCACGAAAGAACAGATGGACAAGAGCTACTTCGACTTGATGCGTGAAAACGTCAAGGCACTTGA
AACTGCTTTGAAATAA

Upstream 100 bases:

>100_bases
TTGACGTGCTCTAAAGGTCACACTATAATATTACTCGCAGTCATAAAACGTAACAGTTACGATTTAATATTCAGATAATT
TGAAAGGTGGAAGATGCTAG

Downstream 100 bases:

>100_bases
TCAAAATCCCGAAACGAATCAACTCGTTTCGGGATTTTTTTATACTTCTATTCGTCGATCTAACATCTTCATCGTGACGA
GAAGCAGAAGCAGTAGCGAT

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKKTWFGAVAAGTLLLGACGNTEGDNASESTDGQLTVYASTFALKSMAEEIGGDRVNVEMVIPPGADPHTYEPTSKQMTQ
IAEADLFLTIGHDLEPYVESMEKSLEGQNVAFVKTAENVKLLDAADTVHVHDEEGHTEDEGHTEDEHAHEEDAHSEDEGH
SEDEHANEEASHSEDEHDHGKYDPHVWLDPTNAVSMAEAVEAAFSEEAPDYKDEFAERLSTFKDEANALDAELRAAVENG
SKSELLVTHAAYGYLAERYGFDQLPIAGLTPSEEPSQQALKRIIEEARLHDLNYIAFEDTVTPKVAEVVKQEIGAESVTI
YNLESVTKEQMDKSYFDLMRENVKALETALK

Sequences:

>Translated_351_residues
MKKTWFGAVAAGTLLLGACGNTEGDNASESTDGQLTVYASTFALKSMAEEIGGDRVNVEMVIPPGADPHTYEPTSKQMTQ
IAEADLFLTIGHDLEPYVESMEKSLEGQNVAFVKTAENVKLLDAADTVHVHDEEGHTEDEGHTEDEHAHEEDAHSEDEGH
SEDEHANEEASHSEDEHDHGKYDPHVWLDPTNAVSMAEAVEAAFSEEAPDYKDEFAERLSTFKDEANALDAELRAAVENG
SKSELLVTHAAYGYLAERYGFDQLPIAGLTPSEEPSQQALKRIIEEARLHDLNYIAFEDTVTPKVAEVVKQEIGAESVTI
YNLESVTKEQMDKSYFDLMRENVKALETALK
>Mature_351_residues
MKKTWFGAVAAGTLLLGACGNTEGDNASESTDGQLTVYASTFALKSMAEEIGGDRVNVEMVIPPGADPHTYEPTSKQMTQ
IAEADLFLTIGHDLEPYVESMEKSLEGQNVAFVKTAENVKLLDAADTVHVHDEEGHTEDEGHTEDEHAHEEDAHSEDEGH
SEDEHANEEASHSEDEHDHGKYDPHVWLDPTNAVSMAEAVEAAFSEEAPDYKDEFAERLSTFKDEANALDAELRAAVENG
SKSELLVTHAAYGYLAERYGFDQLPIAGLTPSEEPSQQALKRIIEEARLHDLNYIAFEDTVTPKVAEVVKQEIGAESVTI
YNLESVTKEQMDKSYFDLMRENVKALETALK

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=317, Percent_Identity=21.1356466876972, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 38669; Mature: 38669

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTWFGAVAAGTLLLGACGNTEGDNASESTDGQLTVYASTFALKSMAEEIGGDRVNVEM
CCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEEEEE
VIPPGADPHTYEPTSKQMTQIAEADLFLTIGHDLEPYVESMEKSLEGQNVAFVKTAENVK
EECCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEE
LLDAADTVHVHDEEGHTEDEGHTEDEHAHEEDAHSEDEGHSEDEHANEEASHSEDEHDHG
EEECCCEEEEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHCCCHHCCCCCCCCCC
KYDPHVWLDPTNAVSMAEAVEAAFSEEAPDYKDEFAERLSTFKDEANALDAELRAAVENG
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSELLVTHAAYGYLAERYGFDQLPIAGLTPSEEPSQQALKRIIEEARLHDLNYIAFEDT
CCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
VTPKVAEVVKQEIGAESVTIYNLESVTKEQMDKSYFDLMRENVKALETALK
CCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTWFGAVAAGTLLLGACGNTEGDNASESTDGQLTVYASTFALKSMAEEIGGDRVNVEM
CCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEEEEE
VIPPGADPHTYEPTSKQMTQIAEADLFLTIGHDLEPYVESMEKSLEGQNVAFVKTAENVK
EECCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEE
LLDAADTVHVHDEEGHTEDEGHTEDEHAHEEDAHSEDEGHSEDEHANEEASHSEDEHDHG
EEECCCEEEEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHCCCHHCCCCCCCCCC
KYDPHVWLDPTNAVSMAEAVEAAFSEEAPDYKDEFAERLSTFKDEANALDAELRAAVENG
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSELLVTHAAYGYLAERYGFDQLPIAGLTPSEEPSQQALKRIIEEARLHDLNYIAFEDT
CCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
VTPKVAEVVKQEIGAESVTIYNLESVTKEQMDKSYFDLMRENVKALETALK
CCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]