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The map label for this gene is fabZ

Identifier: 229917018

GI number: 229917018

Start: 1269074

End: 1269496

Strand: Reverse

Name: fabZ

Synonym: EAT1b_1292

Alternate gene names: 229917018

Gene position: 1269496-1269074 (Counterclockwise)

Preceding gene: 229917019

Following gene: 229917017

Centisome position: 42.32

GC content: 44.44

Gene sequence:

>423_bases
ATGTATACAATTGAGCAAATCAAAGAAGTAATCCCACACAGATACCCGTTTCTGTTAATTGATCGAATTATTGAAGTCGA
GGAAAAGAAGCGTGCTGTTGGATTAAAAAATGTCACGGCGAATGAAGAGTTCTTTAACGGGCATTTCCCAGACTATAATG
TCATGCCAGGTGTCTTGATTGTTGAAGCACTCGCACAAGTCGGTGCTTTTGCAATGTTGAAAGACGAATCGAATCGAGGC
AAGCTTGCCTTTTTTGCAGGGATTGACAACTGCCGTTTCAAACGCCAAGTCGTCCCGGGTGATCAACTTCGTCTCGAGGT
AGAAATCATGAAAATTCGTGGACCAATCGGTAAAGGACATGCCGTGGCCACGGTCGACGGAGAAGTTGCTTGTGAAGCAG
AACTCACTTTCGCCTTGAAGTAA

Upstream 100 bases:

>100_bases
TATAGCGTCATTGGCGGAGGCGATTGGAAAGATGTGTTTGACATCGAGACCTGGCGCCATATCACCGATTTTTGGCTAAC
CTCTTAAAGGCGGTGGATGG

Downstream 100 bases:

>100_bases
GGAGAAATGGGATGCGTGCTTTAGTCATTGTATTATTAGTTGGCTTGATGACGATTGTGGGTTGTCAGCAGCTCCAGACA
GAAGAGTCGAGTGAAGAGAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MYTIEQIKEVIPHRYPFLLIDRIIEVEEKKRAVGLKNVTANEEFFNGHFPDYNVMPGVLIVEALAQVGAFAMLKDESNRG
KLAFFAGIDNCRFKRQVVPGDQLRLEVEIMKIRGPIGKGHAVATVDGEVACEAELTFALK

Sequences:

>Translated_140_residues
MYTIEQIKEVIPHRYPFLLIDRIIEVEEKKRAVGLKNVTANEEFFNGHFPDYNVMPGVLIVEALAQVGAFAMLKDESNRG
KLAFFAGIDNCRFKRQVVPGDQLRLEVEIMKIRGPIGKGHAVATVDGEVACEAELTFALK
>Mature_140_residues
MYTIEQIKEVIPHRYPFLLIDRIIEVEEKKRAVGLKNVTANEEFFNGHFPDYNVMPGVLIVEALAQVGAFAMLKDESNRG
KLAFFAGIDNCRFKRQVVPGDQLRLEVEIMKIRGPIGKGHAVATVDGEVACEAELTFALK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=48.9051094890511, Blast_Score=133, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_EXISA (C4KYQ6)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885664.1
- ProteinModelPortal:   C4KYQ6
- GeneID:   7868719
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1292
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15705; Mature: 15705

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIEQIKEVIPHRYPFLLIDRIIEVEEKKRAVGLKNVTANEEFFNGHFPDYNVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCHHHH
VEALAQVGAFAMLKDESNRGKLAFFAGIDNCRFKRQVVPGDQLRLEVEIMKIRGPIGKGH
HHHHHHHCEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCC
AVATVDGEVACEAELTFALK
EEEEECCCEEEEEEEEEEEC
>Mature Secondary Structure
MYTIEQIKEVIPHRYPFLLIDRIIEVEEKKRAVGLKNVTANEEFFNGHFPDYNVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCHHHH
VEALAQVGAFAMLKDESNRGKLAFFAGIDNCRFKRQVVPGDQLRLEVEIMKIRGPIGKGH
HHHHHHHCEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEEEEECCCCCCC
AVATVDGEVACEAELTFALK
EEEEECCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA