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The map label for this gene is tdcB [H]

Identifier: 229264290

GI number: 229264290

Start: 1724699

End: 1725682

Strand: Direct

Name: tdcB [H]

Synonym: BTH_I1524

Alternate gene names: 229264290

Gene position: 1724699-1725682 (Clockwise)

Preceding gene: 83718729

Following gene: 83720281

Centisome position: 45.28

GC content: 70.02

Gene sequence:

>984_bases
ATGTCTGCTCAACCCGCCTCCGACCTCGTTCTCCCGACCTTCGACGACGTGACCGACGCAGCCGCCCGGCTCGCCGGCGT
CGCGCATCGCACGCCCGTTTTCACGTCCGGCACGGCCGACGCGCGCACGGGCGCGACGATCTTCTTCAAATGCGAGAACT
TCCAGCGGATGGGCGCGTTCAAGTTTCGCGGCGCGTACAACGCGATTTCGCACTTCGACGCCGAGCAGCGCCGTGCGGGC
GTGCTCACGTATTCGTCGGGCAACCATGCGCAGGCGATCGCGCTCGCCGCGCGCCTCGCGGGCATTCACGCGACGATCGT
GATGCCGCACGACGCGCCCGCCGCGAAGGTCGCGGCGACGAAGGGCTACGGCGGCGAAGTCATCACCTACGATCGCTACA
CGGAAAGCCGGGAGGAGATCGGCGCGCGGCTCGCGCAGGAGCGCGGCATGACGCTCGTGCCGCCGTACGACCATCCGCAC
GTGATCGCCGGGCAGGGGACGGCCGCGAAAGAGTTGATCGACGAAGTCGGCGAGATCGACATGCTCGTCGCGCCGCTCGG
CGGCGGCGGGCTGATCGCGGGCACCGCGTTGTCGGCGGCCGCGCTGTCGGCGGGCTGCGCGGTGATCGGCGTCGAGCCGG
AGGCGGGCAACGATGCGCAGCAGTCGCTCGAGCGCGGCGAGGTCGTGCACATTCCGGTGCCGCGGACGATCGCGGACGGC
GCGGCGTCCACGCACGTCGGTGCATACAACTTTCCGATCATCCAGCGGCTCGTCAAGCGGATCGTCACGGCGAGCGACGC
GCAACTCGTCGACACGATGCGTTTCTTCGCGCAGCGGATGAAGATGGTCGTCGAGCCGACCGGCTGTCTCGGCGCGGCGG
CAGTGCTCGACGGCGTGCTGCCCGTCGCGGGCAAGCGCGTCGGCGTGATCCTGAGCGGCGGCAACGTCGATCTCGCGCGC
TACGGCGAGTTCCTGCGCGGGTGA

Upstream 100 bases:

>100_bases
TGGCCGTGCCGCGCCGTTTTCTTTTTCGGCCGCTGCGCGAGTCGGGCGAAGCTGGGACAATGACCGCTTCTTTGTCCAAT
GCGTTTTCGCACTCGCTGCC

Downstream 100 bases:

>100_bases
GCGTGGATGCGGACGGCGCGGCGGCGCGCAACGCGTCGCCCGCCCGCGAGGGCGTCAAGCCGCGCCGCGTTGCCTCAAGC
CGCCGCGTTCAGAATCAGGT

Product: serine/threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSAQPASDLVLPTFDDVTDAAARLAGVAHRTPVFTSGTADARTGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAG
VLTYSSGNHAQAIALAARLAGIHATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPH
VIAGQGTAAKELIDEVGEIDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVHIPVPRTIADG
AASTHVGAYNFPIIQRLVKRIVTASDAQLVDTMRFFAQRMKMVVEPTGCLGAAAVLDGVLPVAGKRVGVILSGGNVDLAR
YGEFLRG

Sequences:

>Translated_327_residues
MSAQPASDLVLPTFDDVTDAAARLAGVAHRTPVFTSGTADARTGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAG
VLTYSSGNHAQAIALAARLAGIHATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPH
VIAGQGTAAKELIDEVGEIDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVHIPVPRTIADG
AASTHVGAYNFPIIQRLVKRIVTASDAQLVDTMRFFAQRMKMVVEPTGCLGAAAVLDGVLPVAGKRVGVILSGGNVDLAR
YGEFLRG
>Mature_326_residues
SAQPASDLVLPTFDDVTDAAARLAGVAHRTPVFTSGTADARTGATIFFKCENFQRMGAFKFRGAYNAISHFDAEQRRAGV
LTYSSGNHAQAIALAARLAGIHATIVMPHDAPAAKVAATKGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHV
IAGQGTAAKELIDEVGEIDMLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVHIPVPRTIADGA
ASTHVGAYNFPIIQRLVKRIVTASDAQLVDTMRFFAQRMKMVVEPTGCLGAAAVLDGVLPVAGKRVGVILSGGNVDLARY
GEFLRG

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=321, Percent_Identity=39.8753894080997, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI19923959, Length=300, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI295821202, Length=181, Percent_Identity=32.0441988950276, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI295821200, Length=181, Percent_Identity=32.0441988950276, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4557415, Length=181, Percent_Identity=32.0441988950276, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI33469958, Length=307, Percent_Identity=27.6872964169381, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789505, Length=318, Percent_Identity=37.1069182389937, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1790207, Length=293, Percent_Identity=35.1535836177474, Blast_Score=151, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17508781, Length=309, Percent_Identity=34.3042071197411, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71991565, Length=310, Percent_Identity=32.5806451612903, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537387, Length=313, Percent_Identity=32.5878594249201, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322631, Length=319, Percent_Identity=58.9341692789969, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320930, Length=304, Percent_Identity=34.8684210526316, Blast_Score=155, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6319788, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355833, Length=314, Percent_Identity=37.2611464968153, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24645328, Length=219, Percent_Identity=36.5296803652968, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 34122; Mature: 33991

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPASDLVLPTFDDVTDAAARLAGVAHRTPVFTSGTADARTGATIFFKCENFQRMGAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCE
KFRGAYNAISHFDAEQRRAGVLTYSSGNHAQAIALAARLAGIHATIVMPHDAPAAKVAAT
EECCHHHHHHHCCHHHHHCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHEEEE
KGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHVIAGQGTAAKELIDEVGEID
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHCCCE
MLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVHIPVPRTIADG
EEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHHCC
AASTHVGAYNFPIIQRLVKRIVTASDAQLVDTMRFFAQRMKMVVEPTGCLGAAAVLDGVL
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHH
PVAGKRVGVILSGGNVDLARYGEFLRG
HCCCCEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SAQPASDLVLPTFDDVTDAAARLAGVAHRTPVFTSGTADARTGATIFFKCENFQRMGAF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHCCCE
KFRGAYNAISHFDAEQRRAGVLTYSSGNHAQAIALAARLAGIHATIVMPHDAPAAKVAAT
EECCHHHHHHHCCHHHHHCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHEEEE
KGYGGEVITYDRYTESREEIGARLAQERGMTLVPPYDHPHVIAGQGTAAKELIDEVGEID
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCHHHHHHHHHCCCE
MLVAPLGGGGLIAGTALSAAALSAGCAVIGVEPEAGNDAQQSLERGEVVHIPVPRTIADG
EEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCHHHCC
AASTHVGAYNFPIIQRLVKRIVTASDAQLVDTMRFFAQRMKMVVEPTGCLGAAAVLDGVL
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHH
PVAGKRVGVILSGGNVDLARYGEFLRG
HCCCCEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA