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The map label for this gene is atpB

Identifier: 229259640

GI number: 229259640

Start: 1529300

End: 1530352

Strand: Direct

Name: atpB

Synonym: LIC11237

Alternate gene names: 229259640

Gene position: 1529300-1530352 (Clockwise)

Preceding gene: 45657119

Following gene: 45657121

Centisome position: 35.75

GC content: 39.89

Gene sequence:

>1053_bases
ATGTATTTAAACCAGATTTCTTTTATGACGAAAAGATTTATCTTCTCTGTATTATTAGTTCTATTATTGCCATTCCAAAT
ATTTGCATCAGGGGAATCAGCTCACGAGGCCTTTGATCTAAACGAAGTGATTGTACATCACCTGATGGACAACGCGGAAT
TTCCGTTTAACATAGGAGGCGTGAAGGTTTTCGAAGGGGAATCCAATTTTGATTCTTCTAAAGAAACGATCTTTACCGAC
CACGAAACCGGAAAACGGTTTCACTTTGTGGGCGGTTTTGATATGCACATCACAAAACGGGTTACGATGATGTGGATTGT
CGCCTTACTTCTTTTTCTTATCTTTATTCCTGCGGCTAAAATTATCGCAAGAAATCCGCTTCAAGTTCAGTCTCGTTTTG
CAAACACCGTAGAAGTATTTGTAAACTTTTTACGCAAGGACATCGTAGACGAAAGTATGCATGGTCACGGCCACGGATAC
TATCATTATATTCTAACCTTATTTTTCTTTATCTTATTTTGTAACTTAATGGGACTGGTTCCATCTGTAGGAGAGTTGAT
CGCAGTAGCAGGAGATGCAACTGGAATGGTGCACTTAGATCATCATAACCCACCTTGGATCGCTAAGGTTTGGAGTGGGA
TCACTGTGACTGGAGATATTTCTGTGACAATGACTCTGGCACTTCTTACTATGTTTCTAATATACGCTGCGGGTTTTATT
TATCAAGGACCTAAGTTCATCTGGCATTCCGTTCCTAACGGAGTTCCTTTACTTTTGTATATCATCATGTGGCCTTTGGA
GTTTATCGTTTCTCCGATGGCAAAAACTTTTGCGCTGACTGTTCGACTTTTAGCCAATATGACAGCAGGGCACGTAATCA
TACTTGCATTGATGGGATTTATCTTTCAATTTCAATCTTGGGGAATCGTTCCTGTTTCGGTGATTGGCTCCGGGTTGATC
TACGTTTTGGAAATCTTTGTAGCTTTCTTACAAGCGTATATTTTCGTATTGCTTACCTCTTTATTCGTAGGATTAAGCAT
GCATAGGCACTGA

Upstream 100 bases:

>100_bases
CCACCGGAATCGCATAAAATACAAAAAAGAAACCGGAAAACATCCGCCAATTCTGTGATAGTGGCCGTAATTAAAATACG
ATCCTTTGTTGATTCGAAAA

Downstream 100 bases:

>100_bases
TTAGAATATTGAATCAACAAGGAGTCAATGGAACCATGGAATTTGGATTAGGATATATTGGTGTAGGAATCGCTGCGGGA
GTTGCCATCCTAGGAGCAGC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MYLNQISFMTKRFIFSVLLVLLLPFQIFASGESAHEAFDLNEVIVHHLMDNAEFPFNIGGVKVFEGESNFDSSKETIFTD
HETGKRFHFVGGFDMHITKRVTMMWIVALLLFLIFIPAAKIIARNPLQVQSRFANTVEVFVNFLRKDIVDESMHGHGHGY
YHYILTLFFFILFCNLMGLVPSVGELIAVAGDATGMVHLDHHNPPWIAKVWSGITVTGDISVTMTLALLTMFLIYAAGFI
YQGPKFIWHSVPNGVPLLLYIIMWPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGFIFQFQSWGIVPVSVIGSGLI
YVLEIFVAFLQAYIFVLLTSLFVGLSMHRH

Sequences:

>Translated_350_residues
MYLNQISFMTKRFIFSVLLVLLLPFQIFASGESAHEAFDLNEVIVHHLMDNAEFPFNIGGVKVFEGESNFDSSKETIFTD
HETGKRFHFVGGFDMHITKRVTMMWIVALLLFLIFIPAAKIIARNPLQVQSRFANTVEVFVNFLRKDIVDESMHGHGHGY
YHYILTLFFFILFCNLMGLVPSVGELIAVAGDATGMVHLDHHNPPWIAKVWSGITVTGDISVTMTLALLTMFLIYAAGFI
YQGPKFIWHSVPNGVPLLLYIIMWPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGFIFQFQSWGIVPVSVIGSGLI
YVLEIFVAFLQAYIFVLLTSLFVGLSMHRH
>Mature_350_residues
MYLNQISFMTKRFIFSVLLVLLLPFQIFASGESAHEAFDLNEVIVHHLMDNAEFPFNIGGVKVFEGESNFDSSKETIFTD
HETGKRFHFVGGFDMHITKRVTMMWIVALLLFLIFIPAAKIIARNPLQVQSRFANTVEVFVNFLRKDIVDESMHGHGHGY
YHYILTLFFFILFCNLMGLVPSVGELIAVAGDATGMVHLDHHNPPWIAKVWSGITVTGDISVTMTLALLTMFLIYAAGFI
YQGPKFIWHSVPNGVPLLLYIIMWPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGFIFQFQSWGIVPVSVIGSGLI
YVLEIFVAFLQAYIFVLLTSLFVGLSMHRH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 39487; Mature: 39487

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLNQISFMTKRFIFSVLLVLLLPFQIFASGESAHEAFDLNEVIVHHLMDNAEFPFNIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCC
VKVFEGESNFDSSKETIFTDHETGKRFHFVGGFDMHITKRVTMMWIVALLLFLIFIPAAK
EEEECCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IIARNPLQVQSRFANTVEVFVNFLRKDIVDESMHGHGHGYYHYILTLFFFILFCNLMGLV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PSVGELIAVAGDATGMVHLDHHNPPWIAKVWSGITVTGDISVTMTLALLTMFLIYAAGFI
CCHHHHHEEECCCCCEEEECCCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
YQGPKFIWHSVPNGVPLLLYIIMWPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGF
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IFQFQSWGIVPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLFVGLSMHRH
HHHHHCCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLNQISFMTKRFIFSVLLVLLLPFQIFASGESAHEAFDLNEVIVHHLMDNAEFPFNIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCC
VKVFEGESNFDSSKETIFTDHETGKRFHFVGGFDMHITKRVTMMWIVALLLFLIFIPAAK
EEEECCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IIARNPLQVQSRFANTVEVFVNFLRKDIVDESMHGHGHGYYHYILTLFFFILFCNLMGLV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PSVGELIAVAGDATGMVHLDHHNPPWIAKVWSGITVTGDISVTMTLALLTMFLIYAAGFI
CCHHHHHEEECCCCCEEEECCCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
YQGPKFIWHSVPNGVPLLLYIIMWPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGF
HCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IFQFQSWGIVPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLFVGLSMHRH
HHHHHCCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA