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The map label for this gene is ribB [H]

Identifier: 229220876

GI number: 229220876

Start: 834959

End: 836074

Strand: Reverse

Name: ribB [H]

Synonym: Reut_A0770

Alternate gene names: 229220876

Gene position: 836074-834959 (Counterclockwise)

Preceding gene: 73540475

Following gene: 73540473

Centisome position: 21.96

GC content: 66.22

Gene sequence:

>1116_bases
ATGACAATCGCCCGTACCGAAGACATCATTGCCGACATCCGTGCCGGCCGCATGGTCATCCTCGTGGATGAAGAAGACCG
CGAAAATGAGGGCGACCTGGTCCTGGCTGCCGATTTCGTCACACCGGATGCGATCAACTTCATGGCCAAGCACGGCCGCG
GCCTGATCTGCCTGACACTGACCGCCGAGCGTTGCCGCCAGCTGAACCTGCAGCCGATGGTGAGCCGCAACGGCACCCAG
CACGGCACCAACTTCACGGTGTCGATCGAAGCAGCGGAAGGCGTGACCACCGGCATTTCGGCGGCTGACCGTTCCCGTAC
CGTAGAGGCGGCCGTCGCGCGCGACGCCAAGCCTTCGGATCTGGTCCAGCCCGGTCACATCTTCCCGCTGACCGCCCAGC
CCGGCGGCGTGCTGATCCGCGCCGGCCATACCGAAGCCGGCTGCGACCTGGGCGCGCTGGCCGGCCTGACGCCCGCCGCC
GTGATCTGCGAGATCATGAAGGACGACGGCACCATGGCGCGCCTGCCCGACCTGATCGAATTCGCCCAGGAACACAACCT
GAAGATCGGCACCATCGCCGACCTGATCCACTACCGCAGCCGCACCGAGAGCATCGTCGAACGCGTTGGCGAGCGCGCCA
TGGAAACGCCGTATGGCACGTTCCACAGCATCGCCTACCGCGACAAGCCGACCGGCCACGCCCACCTGGCGCTGGTCAAG
GGCACGCCCTCGGCGGACAAGGAAACGCTGGTGCGCGTGCATGAGCCGCTGTCGGTGCTGGACCTGCTGGAAGTGTCCCG
CACCACGCACTCGTGGAGCATGCCGGCTGCCCTCGAGGCCATCGCCAAGGCCGAAAGCGGCGTGATGGTGCTGCTGAACT
GCGGCGACTCGGCCGATCAGCTTTTCACGCAATTCACCGCGCTCGACGAACCGCAGAACCGCCCGCGCCGCAAGCCGGAC
CTGCGCACCTATGGCATGGGCGCGCAGATCCTGAAGGATGTGGGCGTCGGCAAGATGCGCGTGCTGGCCGCTGCGCAGCG
CATGCCGAGCATGACGGGCTACGATCTGGAAGTGACCGGCTACCAGCCCATGAACGGGCAGGCCAAGCAAAACTGA

Upstream 100 bases:

>100_bases
CCCATGCCCGGCCGGCGCACACTCCGCAGCATTCCACCGCATGTTTGAGCGGCCGCCTGACAGCTGGCCGCCCCTCGCCC
CTATTTGCCGCCCAGCAGCC

Downstream 100 bases:

>100_bases
ATATCCTGGTGGCCACGCCCTGGCGTCGCCACCATAGCGAACTCTGGAGAACTGAACAATGGATCACGGCTTCTACCCCA
GCAACCTCGACGGTGAAGGC

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTIARTEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPDAINFMAKHGRGLICLTLTAERCRQLNLQPMVSRNGTQ
HGTNFTVSIEAAEGVTTGISAADRSRTVEAAVARDAKPSDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGALAGLTPAA
VICEIMKDDGTMARLPDLIEFAQEHNLKIGTIADLIHYRSRTESIVERVGERAMETPYGTFHSIAYRDKPTGHAHLALVK
GTPSADKETLVRVHEPLSVLDLLEVSRTTHSWSMPAALEAIAKAESGVMVLLNCGDSADQLFTQFTALDEPQNRPRRKPD
LRTYGMGAQILKDVGVGKMRVLAAAQRMPSMTGYDLEVTGYQPMNGQAKQN

Sequences:

>Translated_371_residues
MTIARTEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPDAINFMAKHGRGLICLTLTAERCRQLNLQPMVSRNGTQ
HGTNFTVSIEAAEGVTTGISAADRSRTVEAAVARDAKPSDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGALAGLTPAA
VICEIMKDDGTMARLPDLIEFAQEHNLKIGTIADLIHYRSRTESIVERVGERAMETPYGTFHSIAYRDKPTGHAHLALVK
GTPSADKETLVRVHEPLSVLDLLEVSRTTHSWSMPAALEAIAKAESGVMVLLNCGDSADQLFTQFTALDEPQNRPRRKPD
LRTYGMGAQILKDVGVGKMRVLAAAQRMPSMTGYDLEVTGYQPMNGQAKQN
>Mature_370_residues
TIARTEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPDAINFMAKHGRGLICLTLTAERCRQLNLQPMVSRNGTQH
GTNFTVSIEAAEGVTTGISAADRSRTVEAAVARDAKPSDLVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGALAGLTPAAV
ICEIMKDDGTMARLPDLIEFAQEHNLKIGTIADLIHYRSRTESIVERVGERAMETPYGTFHSIAYRDKPTGHAHLALVKG
TPSADKETLVRVHEPLSVLDLLEVSRTTHSWSMPAALEAIAKAESGVMVLLNCGDSADQLFTQFTALDEPQNRPRRKPDL
RTYGMGAQILKDVGVGKMRVLAAAQRMPSMTGYDLEVTGYQPMNGQAKQN

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=55.7788944723618, Blast_Score=230, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=40.7960199004975, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40160; Mature: 40029

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIARTEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPDAINFMAKHGRGLICLTL
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEE
TAERCRQLNLQPMVSRNGTQHGTNFTVSIEAAEGVTTGISAADRSRTVEAAVARDAKPSD
EHHHHHCCCCCCHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
LVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGALAGLTPAAVICEIMKDDGTMARLPDLIE
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FAQEHNLKIGTIADLIHYRSRTESIVERVGERAMETPYGTFHSIAYRDKPTGHAHLALVK
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCEEEEEEE
GTPSADKETLVRVHEPLSVLDLLEVSRTTHSWSMPAALEAIAKAESGVMVLLNCGDSADQ
CCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHH
LFTQFTALDEPQNRPRRKPDLRTYGMGAQILKDVGVGKMRVLAAAQRMPSMTGYDLEVTG
HHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEC
YQPMNGQAKQN
CCCCCCCCCCC
>Mature Secondary Structure 
TIARTEDIIADIRAGRMVILVDEEDRENEGDLVLAADFVTPDAINFMAKHGRGLICLTL
CCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEE
TAERCRQLNLQPMVSRNGTQHGTNFTVSIEAAEGVTTGISAADRSRTVEAAVARDAKPSD
EHHHHHCCCCCCHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
LVQPGHIFPLTAQPGGVLIRAGHTEAGCDLGALAGLTPAAVICEIMKDDGTMARLPDLIE
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FAQEHNLKIGTIADLIHYRSRTESIVERVGERAMETPYGTFHSIAYRDKPTGHAHLALVK
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCEEEEEEE
GTPSADKETLVRVHEPLSVLDLLEVSRTTHSWSMPAALEAIAKAESGVMVLLNCGDSADQ
CCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHH
LFTQFTALDEPQNRPRRKPDLRTYGMGAQILKDVGVGKMRVLAAAQRMPSMTGYDLEVTG
HHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEC
YQPMNGQAKQN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]