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The map label for this gene is mreB

Identifier: 229089134

GI number: 229089134

Start: 3377698

End: 3378741

Strand: Reverse

Name: mreB

Synonym: S3506

Alternate gene names: 229089134

Gene position: 3378741-3377698 (Counterclockwise)

Preceding gene: 30064583

Following gene: 30064581

Centisome position: 73.46

GC content: 54.5

Gene sequence:

>1044_bases
ATGTTGAAAAAATTTCGTGGCATGTTTTCCAATGACTTGTCCATTGACCTGGGTACTGCGAATACCCTCATTTATGTAAA
AGGACAAGGCATCGTATTGAATGAGCCTTCCGTGGTGGCCATTCGTCAGGATCGTGCCGGTTCACCGAAAAGCGTAGCTG
CAGTAGGTCATGACGCGAAGCAGATGCTGGGCCGTACGCCGGGCAATATTGCTGCCATTCGCCCAATGAAAGACGGCGTT
ATCGCCGACTTCTTCGTGACTGAAAAAATGCTCCAGCACTTCATCAAACAAGTGCACAGCAACAGCTTTATGCGTCCAAG
CCCGCGCGTTCTGGTTTGTGTACCGGTTGGCGCGACCCAGGTTGAACGCCGCGCAATTCGTGAATCCGCGCAGGGCGCTG
GTGCCCGTGAAGTCTTCCTGATTGAAGAACCGATGGCTGCCGCAATTGGTGCTGGCCTGCCGGTTTCTGAAGCGACCGGT
TCTATGGTGGTTGATATCGGTGGTGGTACCACTGAAGTTGCTGTTATCTCCTTGAACGGCGTGGTTTACTCCTCTTCCGT
GCGCATTGGTGGTGATCGTTTCGACGAAGCTATCATCAACTATGTGCGTCGTAATTACGGTTCTCTGATCGGTGAAGCCA
CCGCAGAACGTATCAAGCACGAAATCGGTTCGGCTTACCCGGGCGATGAAGTCCGTGAAATCGAAGTTCGTGGCCGTAAC
CTGGCAGAAGGTGTTCCACGCGGTTTTACCCTGAACTCCAACGAAATCCTCGAAGCACTGCAGGAACCGCTGACCGGTAT
TGTGAGCGCGGTAATGGTTGCACTGGAACAGTGCCCGCCGGAACTGGCTTCCGACATCTCCGAGCGCGGCATGGTGCTCA
CCGGTGGTGGCGCACTGCTGCGTAACCTTGACCGTTTGTTAATGGAAGAAACCGGCATTCCAGTCGTTGTTGCTGAAGAC
CCGCTGACCTGTGTGGCGCGCGGTGGCGGCAAAGCGCTGGAAATGATCGACATGCACGGCGGCGACCTGTTCAGCGAAGA
GTAA

Upstream 100 bases:

>100_bases
CACCGTAGCAGATGATTTTTGCGCCTTGTCGCTGCTGCGTGTGGTTGGTAAAGTAAGCGGATTTTCTTTTCCGCCCCAGC
TTTCAGGATTATCCCTTAGT

Downstream 100 bases:

>100_bases
TCGGATGCAGGCAGGGGAAGCGTCTGTTTACCCTGCCTGGTCTGATACGAGAATACGCATAACTTATGAAGCCAATTTTT
AGCCGTGGCCCGTCGCTACA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE

Sequences:

>Translated_347_residues
MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE
>Mature_347_residues
MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGV
IADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED
PLTCVARGGGKALEMIDMHGGDLFSEE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=100, Blast_Score=696, Evalue=0.0,
Organism=Escherichia coli, GI1786870, Length=342, Percent_Identity=25.7309941520468, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MREB_ECOL6 (P0A9X5)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_755872.2
- ProteinModelPortal:   P0A9X5
- SMR:   P0A9X5
- MINT:   MINT-1222179
- PRIDE:   P0A9X5
- EnsemblBacteria:   EBESCT00000040752
- GeneID:   1040388
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c4006
- GeneTree:   EBGT00050000009552
- HOGENOM:   HBG334976
- OMA:   IINYIRR
- ProtClustDB:   PRK13927
- InterPro:   IPR001023
- InterPro:   IPR004753
- PANTHER:   PTHR19375
- PRINTS:   PR01652
- TIGRFAMs:   TIGR00904

Pfam domain/function: PF06723 MreB_Mbl

EC number: NA

Molecular weight: Translated: 36953; Mature: 36953

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK
CCCHHHCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCEEHHCCHHH
QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHH
VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCH
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL
HHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHH
RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK
CCCHHHCCCCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCEEHHCCHHH
QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHH
VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCH
LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL
HHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHH
RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE
HHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157