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The map label for this gene is adc [H]

Identifier: 227827134

GI number: 227827134

Start: 755435

End: 756217

Strand: Direct

Name: adc [H]

Synonym: M1425_0807

Alternate gene names: 227827134

Gene position: 755435-756217 (Clockwise)

Preceding gene: 227827126

Following gene: 227827136

Centisome position: 28.96

GC content: 37.55

Gene sequence:

>783_bases
ATGAAGGGTAAACTAAACGTAAACCAAGTATTTGCCATGCCTGGTAACGCTCCTCTATATTTGAAACCGCCAGCCTATTA
TAGGGATTGCCCAATACTGATGGGAATATTTAAGGGAAATCCAGACGGAATTAGCGAAACAATACCAGATAACTTAGACT
TAGTAACGTTAGGAGACAATAAGCCATTATTCCTCTATTTCCAAGCGTATTATCCATTTTCAAGCCTTTACGGATCATAT
AACGAAGTTGTGTTAGCCCCCTTAGTCCTTTACCAAAATCAGCCCCATCTCTTCATTTCATACATTTACGTAGATAATGA
CGCTGCTCTTACTGCTGGTAGGGAGATATGGGGATTTCCTAAGAAGTTTGCTAATATGAAATTAGAAATAAAGGGAGAGA
GCGTAGAGGCAAGTTTAGAAAGACCAATTGGAAGAAAGTTAATAAGTGCCCAAATGAGGATTGAGAGGCAGGCGAAGCTA
GAGGAATTGCAATCAACTGGAATTGGTTCGTCTCCAACTCTTCTCCTTAAAATAATTCCTAATCCAGATGCTGAATCTAA
ACCTTCAATAGAATTAGTTAAAGTTGAAGTTAAAATGACGCCTAGAGTTTCAACGAGTGATAATTCCTTGGAATTATGGA
CTGGAAAATTATTACTAAACTTCGTGGAGGAAAGTTTAACGGATCCCTTATTTAAATTCGGTCCAGTGGAATTAGTAAGT
GCCTATTTCGGAAGATTTGACATGATACTGCCACCTGGAAAAGTCATATATAAATATATTTAA

Upstream 100 bases:

>100_bases
ATATATTTAACTATGCAAACTTCTTTTTAAAACTTTATTCTTCTCCGAGAATTTATGATTAAAGTTTATTAAGCTAAAAA
AGAGACATATATATGGGAGT

Downstream 100 bases:

>100_bases
GTGTTTAATTTTTTTATTCTATAAACATAAAGCTTGATAGTAAACTTTATATATTTTTTTAAACTATTCTTAGTATAATG
GAGCTATATTCATTATCTAA

Product: acetoacetate decarboxylase

Products: NA

Alternate protein names: AAD; ADC [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKGKLNVNQVFAMPGNAPLYLKPPAYYRDCPILMGIFKGNPDGISETIPDNLDLVTLGDNKPLFLYFQAYYPFSSLYGSY
NEVVLAPLVLYQNQPHLFISYIYVDNDAALTAGREIWGFPKKFANMKLEIKGESVEASLERPIGRKLISAQMRIERQAKL
EELQSTGIGSSPTLLLKIIPNPDAESKPSIELVKVEVKMTPRVSTSDNSLELWTGKLLLNFVEESLTDPLFKFGPVELVS
AYFGRFDMILPPGKVIYKYI

Sequences:

>Translated_260_residues
MKGKLNVNQVFAMPGNAPLYLKPPAYYRDCPILMGIFKGNPDGISETIPDNLDLVTLGDNKPLFLYFQAYYPFSSLYGSY
NEVVLAPLVLYQNQPHLFISYIYVDNDAALTAGREIWGFPKKFANMKLEIKGESVEASLERPIGRKLISAQMRIERQAKL
EELQSTGIGSSPTLLLKIIPNPDAESKPSIELVKVEVKMTPRVSTSDNSLELWTGKLLLNFVEESLTDPLFKFGPVELVS
AYFGRFDMILPPGKVIYKYI
>Mature_260_residues
MKGKLNVNQVFAMPGNAPLYLKPPAYYRDCPILMGIFKGNPDGISETIPDNLDLVTLGDNKPLFLYFQAYYPFSSLYGSY
NEVVLAPLVLYQNQPHLFISYIYVDNDAALTAGREIWGFPKKFANMKLEIKGESVEASLERPIGRKLISAQMRIERQAKL
EELQSTGIGSSPTLLLKIIPNPDAESKPSIELVKVEVKMTPRVSTSDNSLELWTGKLLLNFVEESLTDPLFKFGPVELVS
AYFGRFDMILPPGKVIYKYI

Specific function: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide [H]

COG id: COG4689

COG function: function code Q; Acetoacetate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010451 [H]

Pfam domain/function: PF06314 ADC [H]

EC number: =4.1.1.4 [H]

Molecular weight: Translated: 29209; Mature: 29209

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKLNVNQVFAMPGNAPLYLKPPAYYRDCPILMGIFKGNPDGISETIPDNLDLVTLGDN
CCCCCCCCEEEECCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHCCCCCCEEEEECCC
KPLFLYFQAYYPFSSLYGSYNEVVLAPLVLYQNQPHLFISYIYVDNDAALTAGREIWGFP
CCEEEEEEEECCHHHHCCCCCHHEEEEEEEECCCCCEEEEEEEEECCCEEECCCHHCCCC
KKFANMKLEIKGESVEASLERPIGRKLISAQMRIERQAKLEELQSTGIGSSPTLLLKIIP
HHHCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
NPDAESKPSIELVKVEVKMTPRVSTSDNSLELWTGKLLLNFVEESLTDPLFKFGPVELVS
CCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHCCHHHHHH
AYFGRFDMILPPGKVIYKYI
HHHCCEEEECCCCCEEEEEC
>Mature Secondary Structure
MKGKLNVNQVFAMPGNAPLYLKPPAYYRDCPILMGIFKGNPDGISETIPDNLDLVTLGDN
CCCCCCCCEEEECCCCCCEEECCCCCCCCCCEEEEEECCCCCCCHHCCCCCCEEEEECCC
KPLFLYFQAYYPFSSLYGSYNEVVLAPLVLYQNQPHLFISYIYVDNDAALTAGREIWGFP
CCEEEEEEEECCHHHHCCCCCHHEEEEEEEECCCCCEEEEEEEEECCCEEECCCHHCCCC
KKFANMKLEIKGESVEASLERPIGRKLISAQMRIERQAKLEELQSTGIGSSPTLLLKIIP
HHHCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
NPDAESKPSIELVKVEVKMTPRVSTSDNSLELWTGKLLLNFVEESLTDPLFKFGPVELVS
CCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCHHHHCCHHHHHH
AYFGRFDMILPPGKVIYKYI
HHHCCEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA