Definition Bacillus anthracis str. CDC 684, complete genome.
Accession NC_012581
Length 5,230,115

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The map label for this gene is ypdA [H]

Identifier: 227815658

GI number: 227815658

Start: 2805039

End: 2806019

Strand: Reverse

Name: ypdA [H]

Synonym: BAMEG_3077

Alternate gene names: 227815658

Gene position: 2806019-2805039 (Counterclockwise)

Preceding gene: 227815659

Following gene: 227815656

Centisome position: 53.65

GC content: 37.61

Gene sequence:

>981_bases
ATGCAGAAAGAAACAGCTATCATAATTGGAGGCGGTCCGTGCGGATTAGCAGCAGCAATTTCGTTGCAAAAGGTAGGGAT
AAATCCGTTAGTAATTGAAAAAGGAAACATTGTAAATGCGATTTATAATTATCCAACTCATCAAACATTTTTCTCTTCTA
GTGAAAAATTAGAAATTGGTGATGTAGCTTTTATTACAGAAAATCGTAAGCCTGTTCGAAATCAAGCGCTTGCGTATTAT
CGTGAAGTAGTAAAGCGTAAATCTGTACGTGTAAATGCTTTTGAACGAGTGGAGAAAGTTCAAAAAGATGGAGAAGTTTT
TCAGGTTGAAACGACAAAGCGTGACGGAAGTAAAGAAATATATATAGCGAAATATATTGTTGTAGCAACTGAATATTACG
ACAATCCAAATTATATGAATGTTCCAGGTGAGGAATTGAAGAAAGTAGCTCATTATTTTAAAGAGGGGCATCCTTATTTT
GACCGAGATGTAGTAGTTATAGGTGGAAAAAACTCGAGTGTAGATGCCGCGTTAGAACTTGTTAAAGCCGGTGCACGTGT
AACGGTACTATATCGCGGAAGTGAGTATTCACCAAGTATAAAGCCGTGGATTTTGCCGGAGTTTGAGGCATTAGTACGAA
ACGGTACAATTCAAATGCATTTCGGGGCTCATGTGAAAGAAATTACTGAACATACATTAACGTATACAGTTGATGGTGAG
GCAAATACAATCCAAAATGATTTTGTGTTTGCGATGACTGGTTACCATCCTGATCATAGTTTCTTAACAAAGATGGGTGT
TCGGATTGATGAAGCGACAGGACGTCCAATTTATGCAGAGGATACGATGGAAACGAACGCTGCAAATATTTTCATTGCAG
GTGTAATTGCTGCTGGAAATAATGCAAATGAAATATTTATTGAGAACGGTCGATTTCATGGAGATGCAATTGCGCAAACC
ATTGCGACAAGAGAAATATAA

Upstream 100 bases:

>100_bases
GAAAAATGAATACAATAAAGATAGGTGCCTACTGCTGTAAGTAGGTTTTTTCTTGTTTTTATAAATAGTGTATTGGTAGA
AGACTAGGAGTGAACCGAGT

Downstream 100 bases:

>100_bases
AAAGAAGCTGTCGAAATAAACTTCGACAGCTTCTTTTTTAATCGTGCATAAACATATTTTGGATTGCTTCATGAGAAGTT
GTATTCTCTAATGCAACTAA

Product: pyridine nucleotide-disulfide oxidoreductase family protein

Products: thioredoxin disulfide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQKETAIIIGGGPCGLAAAISLQKVGINPLVIEKGNIVNAIYNYPTHQTFFSSSEKLEIGDVAFITENRKPVRNQALAYY
REVVKRKSVRVNAFERVEKVQKDGEVFQVETTKRDGSKEIYIAKYIVVATEYYDNPNYMNVPGEELKKVAHYFKEGHPYF
DRDVVVIGGKNSSVDAALELVKAGARVTVLYRGSEYSPSIKPWILPEFEALVRNGTIQMHFGAHVKEITEHTLTYTVDGE
ANTIQNDFVFAMTGYHPDHSFLTKMGVRIDEATGRPIYAEDTMETNAANIFIAGVIAAGNNANEIFIENGRFHGDAIAQT
IATREI

Sequences:

>Translated_326_residues
MQKETAIIIGGGPCGLAAAISLQKVGINPLVIEKGNIVNAIYNYPTHQTFFSSSEKLEIGDVAFITENRKPVRNQALAYY
REVVKRKSVRVNAFERVEKVQKDGEVFQVETTKRDGSKEIYIAKYIVVATEYYDNPNYMNVPGEELKKVAHYFKEGHPYF
DRDVVVIGGKNSSVDAALELVKAGARVTVLYRGSEYSPSIKPWILPEFEALVRNGTIQMHFGAHVKEITEHTLTYTVDGE
ANTIQNDFVFAMTGYHPDHSFLTKMGVRIDEATGRPIYAEDTMETNAANIFIAGVIAAGNNANEIFIENGRFHGDAIAQT
IATREI
>Mature_326_residues
MQKETAIIIGGGPCGLAAAISLQKVGINPLVIEKGNIVNAIYNYPTHQTFFSSSEKLEIGDVAFITENRKPVRNQALAYY
REVVKRKSVRVNAFERVEKVQKDGEVFQVETTKRDGSKEIYIAKYIVVATEYYDNPNYMNVPGEELKKVAHYFKEGHPYF
DRDVVVIGGKNSSVDAALELVKAGARVTVLYRGSEYSPSIKPWILPEFEALVRNGTIQMHFGAHVKEITEHTLTYTVDGE
ANTIQNDFVFAMTGYHPDHSFLTKMGVRIDEATGRPIYAEDTMETNAANIFIAGVIAAGNNANEIFIENGRFHGDAIAQT
IATREI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.8.1.9

Molecular weight: Translated: 36291; Mature: 36291

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00496 PII_GLNB_UMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKETAIIIGGGPCGLAAAISLQKVGINPLVIEKGNIVNAIYNYPTHQTFFSSSEKLEIG
CCCCEEEEECCCCCCHHHHEEHEECCCCEEEEECCCEEEEEECCCCCHHHCCCCCCEEEC
DVAFITENRKPVRNQALAYYREVVKRKSVRVNAFERVEKVQKDGEVFQVETTKRDGSKEI
EEEEEECCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCEEEEEECCCCCCCEE
YIAKYIVVATEYYDNPNYMNVPGEELKKVAHYFKEGHPYFDRDVVVIGGKNSSVDAALEL
EEEEEEEEEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHH
VKAGARVTVLYRGSEYSPSIKPWILPEFEALVRNGTIQMHFGAHVKEITEHTLTYTVDGE
HHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHCCEEEEEECCC
ANTIQNDFVFAMTGYHPDHSFLTKMGVRIDEATGRPIYAEDTMETNAANIFIAGVIAAGN
CCEECCCEEEEEECCCCCHHHHHHHCCEEECCCCCEEEECCCCCCCCCEEEEEEEEEECC
NANEIFIENGRFHGDAIAQTIATREI
CCCEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQKETAIIIGGGPCGLAAAISLQKVGINPLVIEKGNIVNAIYNYPTHQTFFSSSEKLEIG
CCCCEEEEECCCCCCHHHHEEHEECCCCEEEEECCCEEEEEECCCCCHHHCCCCCCEEEC
DVAFITENRKPVRNQALAYYREVVKRKSVRVNAFERVEKVQKDGEVFQVETTKRDGSKEI
EEEEEECCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCEEEEEECCCCCCCEE
YIAKYIVVATEYYDNPNYMNVPGEELKKVAHYFKEGHPYFDRDVVVIGGKNSSVDAALEL
EEEEEEEEEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHH
VKAGARVTVLYRGSEYSPSIKPWILPEFEALVRNGTIQMHFGAHVKEITEHTLTYTVDGE
HHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHCCEEEEEECCC
ANTIQNDFVFAMTGYHPDHSFLTKMGVRIDEATGRPIYAEDTMETNAANIFIAGVIAAGN
CCEECCCEEEEEECCCCCHHHHHHHCCEEECCCCCEEEECCCCCCCCCEEEEEEEEEECC
NANEIFIENGRFHGDAIAQTIATREI
CCCEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: thioredoxin; NADP+

Specific reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]