Click here to switch to the map view.

The map label for this gene is maP2 [H]

Identifier: 227815587

GI number: 227815587

Start: 2741625

End: 2742371

Strand: Reverse

Name: maP2 [H]

Synonym: BAMEG_3005

Alternate gene names: 227815587

Gene position: 2742371-2741625 (Counterclockwise)

Preceding gene: 227815589

Following gene: 227815586

Centisome position: 52.43

GC content: 36.55

Gene sequence:

>747_bases
ATGATTACAATTAAAACGAAAAATGAAATAGATTTAATGCATGAATCTGGAAAGTTACTTGCTTCATGTCATAGAGAAAT
TGCAAAGATAATGAAACCAGGTATTACAACAAAAGGAATTAATACGTTTGTGGAAACGTATTTAGAAAAACATGGTGCAA
CGTCCGAGCAGAAAGGTTACAACGGATATCCTTATGCGGTATGTGCATCTGTAAACGATGAAATGTGTCATGGGTTTCCG
AATGAGATTCCTTTAAACGAGGGTGATATTGTAACAATTGATATGGTAGTAAACTTAAATGGTGGTCTTTCAGATTCTGC
TTGGACATATATAGTTGGAAATGTTTCTGATGAAGCAGAAAGACTATTGTTAGTAGCTGAAAATGCTTTGTATAAAGGAA
TTGATCAGGCGGTGATCGGTAATCGTGTAGGAGACATTGGCTATGCAATTGAGAGTTATGTAGCAAATGAAGGTTTTTCT
GTCGCGAGAGACTTCACTGGACATGGGATTGGTAAAAAGATTCATGAAGAACCAGCAATTTTTCATTTTGGGAAGCAAGG
TCAAGGGCCAGAGCTACAAGAAGGGATGGTAATTACGATTGAGCCGATTGTCAATGTAGGTATGCGATATTGTAAAGTAG
ATTTAAATGGATGGACTGCAAGAACGATGGATGGGAAATTATCAGCTCAATATGAGCATACAATTGTGATTACAAAAGAT
GGGCCAATCATTTTAACGAAGTTGTAA

Upstream 100 bases:

>100_bases
AAATACTAGATGTAATATTAATTGAAAGTGTTGGAAGAGTATGTGTATGATTGAAATTTAGTAGCAAATAGTAGGTCTAG
CAAGGAAGGTAGAGATAAGC

Downstream 100 bases:

>100_bases
TTTGGAATGAAAGAGTTTACAAAACTCGAACGAAAATGATGTTTTTATAAAATTTGTACGTGTTTTATGAATAAAAGCTT
TTCAAAGTATAAAAAGTGCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKGINTFVETYLEKHGATSEQKGYNGYPYAVCASVNDEMCHGFP
NEIPLNEGDIVTIDMVVNLNGGLSDSAWTYIVGNVSDEAERLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFS
VARDFTGHGIGKKIHEEPAIFHFGKQGQGPELQEGMVITIEPIVNVGMRYCKVDLNGWTARTMDGKLSAQYEHTIVITKD
GPIILTKL

Sequences:

>Translated_248_residues
MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKGINTFVETYLEKHGATSEQKGYNGYPYAVCASVNDEMCHGFP
NEIPLNEGDIVTIDMVVNLNGGLSDSAWTYIVGNVSDEAERLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFS
VARDFTGHGIGKKIHEEPAIFHFGKQGQGPELQEGMVITIEPIVNVGMRYCKVDLNGWTARTMDGKLSAQYEHTIVITKD
GPIILTKL
>Mature_248_residues
MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKGINTFVETYLEKHGATSEQKGYNGYPYAVCASVNDEMCHGFP
NEIPLNEGDIVTIDMVVNLNGGLSDSAWTYIVGNVSDEAERLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFS
VARDFTGHGIGKKIHEEPAIFHFGKQGQGPELQEGMVITIEPIVNVGMRYCKVDLNGWTARTMDGKLSAQYEHTIVITKD
GPIILTKL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=37.246963562753, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=35.7142857142857, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=41.1290322580645, Blast_Score=190, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI71996291, Length=248, Percent_Identity=33.0645161290323, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323273, Length=227, Percent_Identity=37.0044052863436, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=38.0566801619433, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=37.7049180327869, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27149; Mature: 27149

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKGINTFVETYLEKHGATSEQKGY
CEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
NGYPYAVCASVNDEMCHGFPNEIPLNEGDIVTIDMVVNLNGGLSDSAWTYIVGNVSDEAE
CCCCEEEEECCCHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHH
RLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFSVARDFTGHGIGKKIHEEPAI
EEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHCCCCCE
FHFGKQGQGPELQEGMVITIEPIVNVGMRYCKVDLNGWTARTMDGKLSAQYEHTIVITKD
EEECCCCCCCCCCCCEEEEEHHHHHCCCEEEEEECCCCEEEECCCCEEEEEEEEEEEECC
GPIILTKL
CCEEEEEC
>Mature Secondary Structure
MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKGINTFVETYLEKHGATSEQKGY
CEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
NGYPYAVCASVNDEMCHGFPNEIPLNEGDIVTIDMVVNLNGGLSDSAWTYIVGNVSDEAE
CCCCEEEEECCCHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCHH
RLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFSVARDFTGHGIGKKIHEEPAI
EEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHCCCCCE
FHFGKQGQGPELQEGMVITIEPIVNVGMRYCKVDLNGWTARTMDGKLSAQYEHTIVITKD
EEECCCCCCCCCCCCEEEEEHHHHHCCCEEEEEECCCCEEEECCCCEEEEEEEEEEEECC
GPIILTKL
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192928; 11058132 [H]