| Definition | Bacillus anthracis str. CDC 684, complete genome. |
|---|---|
| Accession | NC_012581 |
| Length | 5,230,115 |
Click here to switch to the map view.
The map label for this gene is livF [H]
Identifier: 227815246
GI number: 227815246
Start: 2418196
End: 2418897
Strand: Reverse
Name: livF [H]
Synonym: BAMEG_2657
Alternate gene names: 227815246
Gene position: 2418897-2418196 (Counterclockwise)
Preceding gene: 227815247
Following gene: 227815245
Centisome position: 46.25
GC content: 34.05
Gene sequence:
>702_bases GTGGCACTATTACAAGTGAATAATATAGAGACGTATTTAGATCAGTTTCATATTTTACAAGGGGTATCTCTTGCTGTTGA AAAAGGAACGATTACTGTACTGTTTGGGAGAAATGGTGCAGGGAAGACTACGACATTACGTTCGGTTATGGGATTTCACC ATATTGCACATGGTGAAATTTATTATGATCGTACACAAGTAAATGGATTGTCTACACATTTAATTTCAAGGAAAGGAATA GGGTATGTACCAGAAAATCAAGGTATCTTTCACGACCTGACAATAGAAGAAACATTCGCTCTTGCTAGAGGTAAGGGTGA AGAAGCGGAAGAAAAAATAGAATGGATGCTTGAACTATTTCCAGATTTAAAGCAATTTTGGCACAAAAAAAGCGGGCTCT TAAGCGGAGGACAAAAGCAAATGCTAGCAATTTCAAGAGCGTTTATTAATAGTGATGGTTTATTACTTATTGATGAGCCG AGTAAAGGCTTGTCCCCCATTATGATAGAAAAGTTAATGATAGCCATTTTAAAAATGAAAGAGAAAACAACAGTTTTACT CGTTGAACAAAATTTTATGATGGCTAGTCAAATTGGTGATTACTTTTATATTATGGATAATGGAAAAATTGTTCATAACG GTTTTATGCATGAATTAAAAGAGGATAAGGAAATGTGTCATAAATATTTAGGAATCTCTTAA
Upstream 100 bases:
>100_bases CTTATCGTTTTATTCCATGGAGAGTTATTGGCGGAGGGTATGCCTGAAGAAATTATGAAAGATGAGCGAGTACAAAGTGC TTATTTAGGGGGATTATATA
Downstream 100 bases:
>100_bases CATGAATCCGAGGTGAGAAGGATGGATGTGTTAATCAATTTATTTGTAAATGGGATTTCAACAGGGATGCTCATTTTTTT ATTAGCATCAGGTCTTTCGC
Product: branched-chain amino acid ABC transporter, ATP-binding protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 233; Mature: 232
Protein sequence:
>233_residues MALLQVNNIETYLDQFHILQGVSLAVEKGTITVLFGRNGAGKTTTLRSVMGFHHIAHGEIYYDRTQVNGLSTHLISRKGI GYVPENQGIFHDLTIEETFALARGKGEEAEEKIEWMLELFPDLKQFWHKKSGLLSGGQKQMLAISRAFINSDGLLLIDEP SKGLSPIMIEKLMIAILKMKEKTTVLLVEQNFMMASQIGDYFYIMDNGKIVHNGFMHELKEDKEMCHKYLGIS
Sequences:
>Translated_233_residues MALLQVNNIETYLDQFHILQGVSLAVEKGTITVLFGRNGAGKTTTLRSVMGFHHIAHGEIYYDRTQVNGLSTHLISRKGI GYVPENQGIFHDLTIEETFALARGKGEEAEEKIEWMLELFPDLKQFWHKKSGLLSGGQKQMLAISRAFINSDGLLLIDEP SKGLSPIMIEKLMIAILKMKEKTTVLLVEQNFMMASQIGDYFYIMDNGKIVHNGFMHELKEDKEMCHKYLGIS >Mature_232_residues ALLQVNNIETYLDQFHILQGVSLAVEKGTITVLFGRNGAGKTTTLRSVMGFHHIAHGEIYYDRTQVNGLSTHLISRKGIG YVPENQGIFHDLTIEETFALARGKGEEAEEKIEWMLELFPDLKQFWHKKSGLLSGGQKQMLAISRAFINSDGLLLIDEPS KGLSPIMIEKLMIAILKMKEKTTVLLVEQNFMMASQIGDYFYIMDNGKIVHNGFMHELKEDKEMCHKYLGIS
Specific function: Probable component of a branched-chain amino-acid transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI116734710, Length=200, Percent_Identity=30, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI31657092, Length=213, Percent_Identity=29.1079812206573, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI45446740, Length=200, Percent_Identity=31.5, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI47078218, Length=200, Percent_Identity=31.5, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI21536376, Length=215, Percent_Identity=28.3720930232558, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI148612844, Length=224, Percent_Identity=28.125, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI255708477, Length=224, Percent_Identity=28.125, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI153792144, Length=202, Percent_Identity=30.6930693069307, Blast_Score=78, Evalue=5e-15, Organism=Homo sapiens, GI105990541, Length=191, Percent_Identity=30.3664921465969, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI9955963, Length=216, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI9961252, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4505771, Length=210, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI9961250, Length=210, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI150417984, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI27881501, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI42490749, Length=222, Percent_Identity=26.1261261261261, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI42741659, Length=218, Percent_Identity=27.9816513761468, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI171184400, Length=213, Percent_Identity=28.6384976525822, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI27262624, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI27262626, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI27477115, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI27436953, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI87082268, Length=232, Percent_Identity=34.9137931034483, Blast_Score=152, Evalue=3e-38, Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=28.4444444444444, Blast_Score=98, Evalue=4e-22, Organism=Escherichia coli, GI87081791, Length=230, Percent_Identity=30, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789593, Length=237, Percent_Identity=28.2700421940928, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789864, Length=252, Percent_Identity=25, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1788225, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786872, Length=232, Percent_Identity=30.6034482758621, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1790162, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1790467, Length=225, Percent_Identity=24.4444444444444, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788761, Length=217, Percent_Identity=28.110599078341, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1786253, Length=222, Percent_Identity=25.6756756756757, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=26.9406392694064, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1790525, Length=217, Percent_Identity=27.1889400921659, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI87081782, Length=225, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1787370, Length=227, Percent_Identity=27.3127753303965, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789032, Length=209, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787112, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=7e-16, Organism=Escherichia coli, GI1786345, Length=224, Percent_Identity=26.3392857142857, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788450, Length=203, Percent_Identity=25.615763546798, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI87082267, Length=215, Percent_Identity=25.5813953488372, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787089, Length=224, Percent_Identity=27.6785714285714, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789873, Length=223, Percent_Identity=26.457399103139, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787712, Length=217, Percent_Identity=25.3456221198157, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1787792, Length=224, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI87081709, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=8e-14, Organism=Escherichia coli, GI1786398, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1786654, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787143, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI48994943, Length=229, Percent_Identity=25.3275109170306, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI48995001, Length=230, Percent_Identity=21.304347826087, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788165, Length=175, Percent_Identity=30.2857142857143, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1786319, Length=226, Percent_Identity=29.646017699115, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786803, Length=215, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI87081834, Length=217, Percent_Identity=24.8847926267281, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1786563, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1788897, Length=204, Percent_Identity=25, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787105, Length=211, Percent_Identity=26.0663507109005, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1788053, Length=164, Percent_Identity=27.4390243902439, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787113, Length=211, Percent_Identity=27.9620853080569, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71983510, Length=209, Percent_Identity=31.1004784688995, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71983523, Length=209, Percent_Identity=31.1004784688995, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71983516, Length=209, Percent_Identity=31.1004784688995, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=27.6497695852535, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565586, Length=206, Percent_Identity=29.126213592233, Blast_Score=80, Evalue=6e-16, Organism=Caenorhabditis elegans, GI115533608, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI25146777, Length=210, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI71996550, Length=222, Percent_Identity=26.5765765765766, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71984940, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71996809, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193211015, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193211017, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193202349, Length=222, Percent_Identity=27.9279279279279, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17541710, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI212646699, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17558664, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193208177, Length=223, Percent_Identity=26.0089686098655, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193209708, Length=214, Percent_Identity=27.1028037383178, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI71992285, Length=214, Percent_Identity=24.7663551401869, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=7e-12, Organism=Drosophila melanogaster, GI221512771, Length=173, Percent_Identity=31.7919075144509, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24666092, Length=228, Percent_Identity=27.6315789473684, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24643674, Length=225, Percent_Identity=29.3333333333333, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI85725262, Length=164, Percent_Identity=28.6585365853659, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24650855, Length=179, Percent_Identity=27.9329608938547, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24650853, Length=179, Percent_Identity=27.9329608938547, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI23397593, Length=213, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI85726357, Length=220, Percent_Identity=25.4545454545455, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI281362751, Length=179, Percent_Identity=27.9329608938547, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24582014, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24582012, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28574744, Length=207, Percent_Identity=24.6376811594203, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24659289, Length=225, Percent_Identity=27.1111111111111, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI21357907, Length=214, Percent_Identity=25.2336448598131, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24648314, Length=219, Percent_Identity=26.027397260274, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574150, Length=212, Percent_Identity=29.2452830188679, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007328, Length=212, Percent_Identity=29.2452830188679, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641565, Length=212, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24649703, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26349; Mature: 26218
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 5.2 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.7 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALLQVNNIETYLDQFHILQGVSLAVEKGTITVLFGRNGAGKTTTLRSVMGFHHIAHGEI CEEEEECCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEE YYDRTQVNGLSTHLISRKGIGYVPENQGIFHDLTIEETFALARGKGEEAEEKIEWMLELF EEEHHHCCCHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHH PDLKQFWHKKSGLLSGGQKQMLAISRAFINSDGLLLIDEPSKGLSPIMIEKLMIAILKMK HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC EKTTVLLVEQNFMMASQIGDYFYIMDNGKIVHNGFMHELKEDKEMCHKYLGIS CCEEEEEEECCHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure ALLQVNNIETYLDQFHILQGVSLAVEKGTITVLFGRNGAGKTTTLRSVMGFHHIAHGEI EEEEECCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEE YYDRTQVNGLSTHLISRKGIGYVPENQGIFHDLTIEETFALARGKGEEAEEKIEWMLELF EEEHHHCCCHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHH PDLKQFWHKKSGLLSGGQKQMLAISRAFINSDGLLLIDEPSKGLSPIMIEKLMIAILKMK HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC EKTTVLLVEQNFMMASQIGDYFYIMDNGKIVHNGFMHELKEDKEMCHKYLGIS CCEEEEEEECCHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]