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The map label for this gene is lytE [H]

Identifier: 227815228

GI number: 227815228

Start: 2399634

End: 2400896

Strand: Reverse

Name: lytE [H]

Synonym: BAMEG_2639

Alternate gene names: 227815228

Gene position: 2400896-2399634 (Counterclockwise)

Preceding gene: 227815229

Following gene: 227815226

Centisome position: 45.91

GC content: 38.95

Gene sequence:

>1263_bases
ATGAAAAAAGTAATTGCAGGTTTAGCAGCAGCTTCTGTAGTAGGTGTTGCAGTTCCAGGTATGGATTCTGCTCAAGCACA
AGTTTCAAACGAAGCGCTAAAAGAAATTAATGGACAAGCTCAAACTCAAACGACTGTAACTGAAACAAAAACTGTAGAAA
CAAAATCTGACTTAAAATACACAGTAACTGCTGATGTATTAAATGTTCGTTCAGGTGCTGGTACAGGACATAGCGTTATT
TCTAAAGTAAAACAAGGTCAAGTACTACAAGTAATTGGACAAGAAAACGGTTGGTTCAAAGTAACTGTAAACGGTCAAAC
TGGTTATGTAAGTGGTGACTTCGTAACAACTGGTGGTAAAACAGGAACTACTGTTCAACAAGGAACTGGTACTTACACAG
TAAACGTTTCTTCACTTAACGTACGTACAGGTCCAAGTACATCTCATACAGTATTAGGCTCTGTAAATAAAGGTAAAACA
GTACAAGTTGTTAGTGAAGTACAAGATTGGTTTAAAATCAACTTCAATGGTGGAACTGGATATGTAAGCAAAGACTTCGT
AACAAAAGGTGGTTCTGCTGTATCTAACCAAACACAACAACCAACTACAAACAACAATACTACAACAGTTCAAACTGGTG
GTTCTTATGTTGTTAACACTGGTGCTCTAAAAGTACGTACAGGCCCAGCTACATACAACGCTGTAATCGGTGGTGTAACA
AACGGTACAGTATTAAACGTTACTGGCGCTGAAAATGGTTGGTACAAAATTAACCATAACGGCCGCACAGGTCACGTAAG
TGCAGACTTCGTTAAGTTTGTAAAAGGCGGAGTAAACAACGTTACGAATAACGTTCAACAACCAGTTAAAGACGTACAAA
AACCAACAACAGGTGGAAATACATCTTCAATCGCTGGATTCGCTAGATCTTTAAATGGTTCACCGTACAGAACTGCTGGT
ACAACACCTGCTGGTTTTGACTGCAGTGGATTCATTCACTACGTATTAAATCAAACTGGTCATAAAGGCGCTCGTCAAAC
AGTTGCTGGATACTGGAGCTCTAAAACAAAAACTAGCAATCCACAACCAGGTGATTTAGTATACTTCCAAAACACTTATA
AATCAGGTCCTTCTCACATGGGTGTTTACTTAGGAAACGGTCAATTCATTAGTGCAGAAACTGATGCAACTGGCGTACGT
ATTAGTTCAGTAAGCAACTCTTACTGGAGCAAGCACCTTTTAGGTTACACAAAAGCATACTAA

Upstream 100 bases:

>100_bases
AATGGAACTTAATGAATATTTTACTTTGATAATATTGTAAAGTATTAAGTTTATAAGTTTTTTAAAAGAGGATAGTAGGG
AAAGGAAGTAAAGACAACTT

Downstream 100 bases:

>100_bases
GAAAAAGTAGTTTATATACTTTTCGAATAGAGAAAAGGCTTTCCAGGGAAACTTGGGAAGCCTTTTTATAGTTGAATAAA
TTGGGAGTATAGTAGTTTTT

Product: putative cell wall peptidase, NlpC/P60 family

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKVIAGLAAASVVGVAVPGMDSAQAQVSNEALKEINGQAQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVI
SKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKT
VQVVSEVQDWFKINFNGGTGYVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVT
NGTVLNVTGAENGWYKINHNGRTGHVSADFVKFVKGGVNNVTNNVQQPVKDVQKPTTGGNTSSIAGFARSLNGSPYRTAG
TTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVR
ISSVSNSYWSKHLLGYTKAY

Sequences:

>Translated_420_residues
MKKVIAGLAAASVVGVAVPGMDSAQAQVSNEALKEINGQAQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVI
SKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKT
VQVVSEVQDWFKINFNGGTGYVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVT
NGTVLNVTGAENGWYKINHNGRTGHVSADFVKFVKGGVNNVTNNVQQPVKDVQKPTTGGNTSSIAGFARSLNGSPYRTAG
TTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVR
ISSVSNSYWSKHLLGYTKAY
>Mature_420_residues
MKKVIAGLAAASVVGVAVPGMDSAQAQVSNEALKEINGQAQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVI
SKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKT
VQVVSEVQDWFKINFNGGTGYVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVT
NGTVLNVTGAENGWYKINHNGRTGHVSADFVKFVKGGVNNVTNNVQQPVKDVQKPTTGGNTSSIAGFARSLNGSPYRTAG
TTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVR
ISSVSNSYWSKHLLGYTKAY

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=108, Percent_Identity=35.1851851851852, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787944, Length=108, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788501, Length=102, Percent_Identity=40.1960784313725, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 43927; Mature: 43927

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIAGLAAASVVGVAVPGMDSAQAQVSNEALKEINGQAQTQTTVTETKTVETKSDLKY
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEE
TVTADVLNVRSGAGTGHSVISKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGK
EEEEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEECCEEECCCC
TGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKTVQVVSEVQDWFKINFNGGTG
CCCEEECCCCEEEEEEEEEEEECCCCCCCEEEECCCCCCEEHHHHHCCCEEEEEECCCCC
YVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVT
CEEHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEEECCCEEEEEEECCC
NGTVLNVTGAENGWYKINHNGRTGHVSADFVKFVKGGVNNVTNNVQQPVKDVQKPTTGGN
CCEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
TSSIAGFARSLNGSPYRTAGTTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSN
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCCC
PQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLLGYTKAY
CCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVIAGLAAASVVGVAVPGMDSAQAQVSNEALKEINGQAQTQTTVTETKTVETKSDLKY
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEE
TVTADVLNVRSGAGTGHSVISKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGK
EEEEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCEEECCEEECCCC
TGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKTVQVVSEVQDWFKINFNGGTG
CCCEEECCCCEEEEEEEEEEEECCCCCCCEEEECCCCCCEEHHHHHCCCEEEEEECCCCC
YVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVT
CEEHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEEECCCEEEEEEECCC
NGTVLNVTGAENGWYKINHNGRTGHVSADFVKFVKGGVNNVTNNVQQPVKDVQKPTTGGN
CCEEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
TSSIAGFARSLNGSPYRTAGTTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSN
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCCC
PQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLLGYTKAY
CCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]